Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] from ATCC

Product Specs
ItemHep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B]
CompanyATCC
Price $431.00Supplier Page View Company Product Page
Catalog NumberHB-8064
ApplicationsThis cell line is a suitable transfection host
TypeCell Biology
SpeciesHomo sapiens
TissueLiver
Cell LineHep 3B2.1-7
Validated Species ReactivityHuman (Hu)
Tissue (standardized)Liver
Age8 years
DiseaseCarcinoma Hepatocellular

Specifications/Features

Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinomaCell Reports MedicineApril 21, 2026Elena Adan-Villaescusa, Borja Castello-Uribe, Iker Uriarte, Eva Santamaria, Roberto Barbero, Miriam Belzunce, Amaya López-Pascual, Maria Ujue Latasa, Jasmin Elurbide, Emiliana Valbuena-Goiricelaya, et al.Bank,N/A Human: PLC/PRF/5,ATCC,Cat# CRL-8024 ™ Human: SNU449,ATCC,Cat# CRL-2234 ™ Human: Hep3B,ATCC,Cat# HB-8064 ™ ,, Experimental models: Organisms/strains,Experimental models: Organisms/strains,Experimental models:

(2) Cathepsin Inhibitor Suppresses the Growth of Ectopic Hepatocellular Carcinoma Tumors in Mouse ModelsACS Pharmacology & Translational ScienceApril 10, 2026Olamide Crown, Oluwatoyin V. Odubanjo, Olawale S. Adeyinka, Felicite K. Noubissi, Ifedayo Victor OgungbeMethods Antiproliferation Assay Hepatocellular carcinoma cell lines Hep G2 (CRL-11997) and Hep 3B2.1–7 (ATCC-HB-8064) were used for the antiproliferation assays. The cells were grown in Dulbecco’s Modified Eagle’s Medium (DMEM

(3) Deep-learning-based de novo discovery and design of therapeutics that reverse disease-associated transcriptional phenotypesCellMarch 17, 2026Jing Xing, Mingdian Tan, Dmitry Leshchiner, Mengying Sun, Mohamed Abdelgied, Li Huang, Shreya Paithankar, Katie Uhl, Rama Shankar, Erika Lisabeth, et al.RRID: CVCL_0336 Human: HepG2,ATCC,"Cat# HB-8065, Cellosaurus RRID: CVCL_0027" Human: Hep3B,ATCC,"Cat# HB-8064, Cellosaurus RRID: CVCL_0326" Human: Primary hepatocytes,Sekisui XenoTech,Cat# CHP48 Experimental models

(4) Decoding the circRNA-miRNA-mRNA regulatory network in hepatitis B virus-driven hepatocellular carcinomaCell Communication and SignalingMarch 17, 2026Kainat Ahmed, Anwaruddin Mohammad, Nan Chaiyariti, Danya Sankaranarayanan, Pankaj Kumar, Sudhakar Jhaon the integrated HBV phase. Methods Cell culture Hep3B, HBV-integrated HCC cell line (Cat. No. HB-8064) and HepG2, HBV-negative HCC cell line (Cat. No. HB-8065) were purchased from ATCC. Cells were cultured

(5) Calixarene-Based Nanostructures for Delivering Coumarin 6 for Tumor-Cell Imaging and Photoinduced ToxicityACS Applied Nano MaterialsMarch 13, 2026Loredana Ferreri, Giuseppe Granata, Giuseppe Forte, Melchiorre Cervello, Antonella Cusimano, Salvatore Petralia, Grazia Maria Letizia ConsoliHep3B, SNU398, and SNU475 were acquired from the American Type Culture Collection (ATCC) (HB-8065, HB-8064, CRL-2233, and CRL-2236, respectively), Huh7 cells were a gift from Prof. M. Levrero (Sapienza University

(6) Enzyme-Targeted Antiproliferative Effects of Novel Indole-Acrylamide Xenobiotics Acting on Cyclooxygenase PathwaysJ XenobiotMarch 4, 2026Mohammed Hawash, Benay Mahmutoğlu, Murad Abualhasan, Deniz Cansen Kahraman, Sultan Nacak Baytasin vitro against eleven cancer cell lines, including human HCC cell lines (Huh7:JCRB0403, Hep3B: ATCC-HB-8064, HepG2: ATCC-HB-8065), Mahlavu [30] and SNU475: ATCC-CRL-2236), colon cancer cell lines (HCT116: ATCC-CCL-247)

(7) Matriptase-2-mediated suppression of hepatic hepcidin expression in mice requires hepatocyte neogeninJournal of Biological ChemistryMarch 1, 2026Caroline A. Enns, Shall Jue, An-Sheng ZhangMolecular Virology Support Core, OHSU. Cell line and transfection We obtained Hep3B cells from ATCC (#HB-8064). We used Hep3B cells for transient co-transfection of pCMV6-fNeo1 with pEGFP-N1 (EGFP) or pCMV6-fMt2

(8) Pericentromeric Transcription of Novel Pathogen-Related Human GPS Genes in Cancers is Regulated by C19MC miRNAs, CEBPB, IFN-γ, and IFN-βResearchSquareFebruary 4, 2026Goodwin Jinesh, Isha Godwin, Marco Napoli, Elsa Flores, Andrew Brohlculture and authentication by DNA fingerprinting. Human Hep3B hepatocellular carcinoma cells (ATCC # HB-8064), and MCF-7 (HTB22) human breast cancer cells were cultured in MEM containing L-Glutamine and Sodium

(9) Label‐free imaging of intracellular structures in living mammalian cells via external apodization phase‐contrast microscopyThe FEBS JournalFebruary 1, 2026Hiroshi Ohno, Takenori Nishimura, Kenta Kainoh, Yoshitaka Ohashi, Naoko Onodera, Mayuko Kano, Lay Nurhana Sari, Masato Masuda, Yoshiaki Tamura, Teppei Nishino, et al.HCT116 cells (RRID:CVCL_0291, ATCC CCL‐247), human hepatocellular carcinoma Hep 3B cells (RRID:CVCL_0326, ATCC HB‐8064), mouse fibroblast NIH/3T3 cells (RRID:CVCL_0594, ATCC CRL‐1658), human breast adenocarcinoma MDA‐MB‐231 cells

(10) Ethyl acetate fraction of Curcuma longa leaves suppresses IL‑6‑induced STAT3 activation via ERK signaling in Hep3B cellsBiomedical ReportsJanuary 20, 2026Hyun-Jae Jang, Yuri Kang, Eun-Jae Park, Eunmi Park, Woonjung Kim, Soyoung Lee, Seung Woong Leecell culture Human hepatoma Hep3B cells were obtained from the American Type Culture Collection (ATCC; no. HB-8064) and were maintained in DMEM supplemented with 10% fetal bovine serum, 50 U/ml penicillin, and 50 mg/ml

(11) Impaired nitrogenous waste clearance promotes hepatocellular carcinomaScience AdvancesJanuary 9, 2026Xinlu Han, Jianliang Shen, Junrong Yan, Rahul Tacke, Weiwei Dai, Qingqing Mao, Heineken Queen Daguplo, Shuyang Liu, Ariful Islam, Tong Liu, et al.using Plasmid Maxi Kit (Qiagen, 12163). Cell lines Hep3B [American Type Culture Collection (ATCC) HB-8064], Hep G2 (ATCC, HB-8065), SK-Hep-1 (ATCC, HTB-52), THLE-2 (ATCC, CRL-2706), PLC/PRF/5 (ATCC, CRL-8024),

(12) Synthesis, Crystal Structure, Antitumor, and Antimicrobial Activity of Novel Copper(II) Complexes with a Coumarin Derivative Containing a Histamine SubstituentMoleculesJanuary 1, 2026Ewelina Namiecińska, Pawel Hikisz, Patryk Czapnik, Magdalena Małecka, Magdalena Grazul, Peter Mayer, Ingo-Peter Lorenz, Elzbieta Budziszleukemia HL60 line (ATCC® CCL-240™, promyelocytic leukemia), hepatocellular carcinoma Hep3B line (ATCC® HB-8064), and the malignant melanoma WM-115 cell line (91061232, human skin, epithelial). All but one cell line

(13) Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinomaiScienceNovember 21, 2025Ying Zhang, Xiaohong Cui, Jing Du, Ge Cui, Yuhang Ling, Chengwu Tanglines ,, HEK293T,ATCC,CRL-3216; RRID:CVCL_0063 Hep-G2,ATCC,HB-8065; RRID:CVCL_0027 Hep 3B,ATCC,HB-8064; RRID:CVCL_0326 SK-HEP-1,ATCC,HTB-52; RRID:CVCL_0525 SW620,ATCC,CCL-227; RRID:CVCL_0547 HT-29,ATCC,HTB-38;

(14) CEBPB, C19MC, and Defective Autophagy Drive Novel Podosomal Belt to Macropinocytosis Transition, Lipid Accumulation, and HBV A-to-I RNA-editingResearch SquareOctober 31, 2025Goodwin Jinesh, Nino Mtchedlidze, Varsha Devarapalli, Santanu Adhikary, John Lockhart, Marco Napoli, Isha Isha, Michelle Reiser, Ling Cen, Xiaoxian Liu, et al.transfections The cells were maintained as described previously8. Briefly, human Hep3B cells (ATCC # HB-8064) were cultured in MEM containing L-Glutamine and Sodium bi-carbonate (Sigma #M4655), with 10% FBS (Sigma#F0926),

(15) The Chromosome 19 microRNA Cluster Facilitates Cancer Stemness in Hepatocellular CarcinomaNon-Coding RNAOctober 29, 2025Marian T. Underwood, Varsha Devarapalli, Goodwin G. Jinesh, John H. Lockhart, Marco Napoli, Nino Mtchedlidze, Elsa R. Flores, Andrew S. Brohlreceiving treatment. 4. Materials and Methods 4.1. Cell Culture Skhep1 (ATCC, HTB-52), Hep3B (ATCC, HB-8064), and HEK293T (ATCC, CRL-11268) cell lines were maintained in Minimum Essential Medium (MEM) (Sigma-Aldrich,

(16) Combining Microwave Ablation With CAR-T-Cell Therapy in Tumor-Bearing Mouse ModelsBIO-PROTOCOLOctober 20, 2025Bihui Cao, Gabrielle L. Wheeler, Jensen Mast, Qi Zhao, Jia Shentherapeutic strategy. Materials and reagents Biological materials 1. Hep3B cells (ATCC, catalog number: HB-8064) 2. SK-HEP-1 cells (ATCC, catalog number: HTB-52) 3. CAR-T cells (generated in-house [16]) 4. NOG (NOD/Shi-scid

(17) The upregulation of GDF15 is controlled epigenetically by oncogenic TCF19 signaling in human hepatocellular carcinomaiScienceOctober 17, 2025Yongqian Liu, Caiyu Yong, Mengyu Yang, Haoxiang Qi, Sijie Zheng, Menglan Wang, Xu Huang, Shujuan Zhao, Qiyi Zhang, Jianwei Han, et al.lines,Experimental models: Cell lines ,, Human: Huh1,JCRB,JCRB0199 Human: Huh7,JCRB,JCRB0403 Human: Hep3B,ATCC,HB-8064 Human: MAHLAVU,CLS,300473 Human: SNU449,KCLB,00449 Human: SNU739,KCLB,00739 Human: SNU886,KCLB,00886 Human:

(18) Regulation of Cell Cycle-Related Damage/Repair Mechanism and Oxidative Stress Status by Oroxylin A in Hepatocellular Carcinoma CellsInternational Journal of Molecular SciencesSeptember 13, 2025Fatma Seçer Çelik, Safaa Altveş, Canan Eroğlu Güneşcandidate for anticancer therapy. 4. Materials and Methods 4.1. Cell Culture and Chemicals Hep3B (ATCC® HB-8064™) hepatocellular carcinoma cell line was obtained from ATCC (Manassas, VA, USA). These cells were grown

(19) ACLY inhibition promotes tumour immunity and suppresses liver cancerNatureSeptember 1, 2025Gautam J, Wu J, Lally JSV, McNicol JD, Fayyazi R, Ahmadi E, Oniciu DC, Heaton S, Newton RS, Rehal S, et al.spectra were analysed using the Xcalibur 2.1 Qualitative software package. Clonogenic assay Hep3B (HB-8064) human hepatocarcinoma and Hepa1-6 (CRL-1830) mouse hepatoma cell lines were purchased from the ATCC

(20) Exploration of the Roles and Mechanisms Between Tumor-Infiltrating Lymphocytes and Hepatocellular Carcinoma Based on Single-Cell TranscriptomicsInt J GenomicsAugust 20, 2025Taiyu Shi, Donghao Cheng, Xinyan Du, Jianning Wang, Siyuan Jiang, Liangyu Yang, Fen Chen, Chenxu Gong, Yan Ou, Bangjie Chen, et al.Cell Culture The human T-cell leukemia cell line TALL-104 (ATCC CRL-11386) and HCC cell line Hep 3B (ATCC HB-8064) were cultured in RPMI-1640 and DMEM (Gibco) supplemented with 10% fetal bovine serum (FBS) (Gibco),

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Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] from ATCC

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ATCC

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Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] from ATCC

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