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Miscellaneous Human Cell Lines
HCT-15
HCT-15 from ATCC
Be the first to write a review!
Citations:
(142)
Supplier Page
Supplier Page from
ATCC for
HCT-15
Request Info
Description
HCT-15 cells were isolated from the large intestine of a male Dukes C colorectal cancer patient and can be used for cancer and toxicology research
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
HCT-15
Company
ATCC
Price
$431.00
Supplier Page
View Company Product Page
Catalog Number
CCL-225
Applications
This cell line is a suitable transfection host
Type
Cell Biology
Species
Homo sapiens
Tissue
Large intestine, Colon
Cell Line
HCT-15
Validated Species Reactivity
Human (Hu)
Tissue (standardized)
Colon, Rectum
Disease
Adenocarcinoma Colorectal Dukes type C
Specifications/Features
Post freeze viability ≥ 50%
Add to Compare List
ATCC
10801 University Boulevard
Manassas
,
Virginia
20110-2209
United States
Phone
: (703) 365-2700
Fax: (703) 365-2701
Company Profile
Website:
http://www.atcc.org
Citations (142)
(1)
CXCL14 Inhibits Colon Cancer Progression by Modulating Tumor Cell Invasion and Immune Microenvironment
Cells
May 8, 2026
Yinjie Zhang, Siyi Wang, Yuchen Niu, Yanjing Wang, Buyong Ma, Jingjing Li
(SRE0098, Sigma-Aldrich, St. Louis, MO, USA). CT26 (
CRL-2638
,
ATCC
, Manassas, VA, USA) and HCT15 cells (
CCL-225
,
ATCC
) were cultured in RPMI1640 medium (Adamas life, Shanghai, China, C8013) with 10% FBS. All cells
(2)
The lipid transfer protein STARD7 controls intestinal tumor development in a context-dependent manner
EMBO Molecular Medicine
March 30, 2026
Kateryna Shostak, Yu Chen, Chloé Maurizy, Gilles Rademaker, Xinyi Xu, Arnaud Blomme, Pierre Close, Olivier Renson, Matthias Van Hul, Patrice D Cani,
et al.
line,
ATCC
,
CCL-228
,
CCL-228
COLO205 cell line,
ATCC
,
CCL-222
,
CCL-222
DLD1 cell line,
ATCC
,
CCL-221
,
CCL-221
HCT15 cell line,
ATCC
,
CCL-225
,
CCL-225
Recombinant DNA,Recombinant DNA,Recombinant DNA,Recombinant DNA Antibodies,Antibodies,Antibodies,Antibodies
STARD7
,PAS-30772,Invitrogen,1/1000
STARD7
,HPA064978,Sigma,1/2000
Chop
,#
2895
,
Cell Signaling Technologies
(3)
Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers
Advanced Science
February 13, 2026
Xu Xiao, Cheng Lu, Hao Chen, Jing Zhou, Yunyun Hu, Haonan Di, Guoqiang Su, Xiaomei Yan
colorectal carcinoma
(
HCT‐15
, RRID: CVCL_0292;
HCT‐116
, RRID: CVCL_0291) were obtained from the
ATCC
(
HCT‐15
,
CCL‐225
;
HCT‐116
,
CCL‐247
) in October 2015. All cell lines have been authenticated using STR profiling. All
(4)
A Global Assessment of the Transcription-Dependent Single Nucleotide Variants Relies on the Characteristics of RNA-Sequencing Technologies
Biomolecules
January 29, 2026
Xia Zhang, Jiawei Liu, Yabing Zhu, Guixue Hou, Mingzhou Bai, Yuxin Li, Wenbo Cui, Siqi Liu
Methods 2.1. Cell Culturing for Cell Lines Five
human
colorectal cancer
cell lines—HCT15 (
ATCC
®
CCL-225
™),
LoVo
(
ATCC
®
CCL-229
™), SW480 (
ATCC
®
CCL-228
™), SW620 (
ATCC
®
CCL-227
™), and HCT116 (
ATCC
®
CCL-247
™)—were
(5)
Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer
Cell Reports Medicine
January 20, 2026
Weixiang Zhan, Yang Fu, Yina Liu, Runkai Cai, Fan Bai, Chenxu Guo, Yi Cheng, Zehua Wu, Ge Qin, Yuqian Xie,
et al.
RRID:CVCL_0399
RKO
,
ATCC
,
CRL-2577
; RRID:CVCL_0504 Ls174T,
ATCC
,
CL-188
; RRID:CVCL_1384 HCT8,
ATCC
,
CCL-244
; RRID:CVCL_2478 HCT15,
ATCC
,
CCL-225
; RRID:CVCL_0292 SW480,
ATCC
,
CCL-228
; RRID:CVCL_0546 SW620,
ATCC
,
CCL-227
; RRID:CVCL_0547 SW48,
ATCC
,
CCL-231
;
(6)
Esketamine Enhances the Chemosensitivity of Colorectal Adenocarcinoma Cells to 5-Fluorouracil via AMPK/mTOR/HMMR Signaling Pathway
Oncology Research
January 19, 2026
Yuerou Feng, Panpan Tong, Shuwen Fu, Xiaofan Lu, Liquan Zheng, Jielan Lai, Renchun Lai
and
Cell Culture
Human
colorectal
adenocarcinoma
cell lines DLD1 (
ATCC
®
CCL-221
™) and HCT15 (
ATCC
®
CCL-225
™) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA). All cell lines
(7)
Intratumoral microbiota-derived S1P sensitizes the combination therapy of Capecitabine and PD-1 inhibitors
iScience
December 19, 2025
Chen-Shu Dai, Tian-Tian Qi, Hui-Ling Shang, Ri-Hua Xie, Hao Liu, Zhen-Ming Liu, Yi-Min Cui, Yu-Hang Zhang
lines ,, SW620,
ATCC
,Cat#
CCL-227
SW480,ATCC,Cat#
CCL-227
HT-29
,
ATCC
,Cat#
HTB-38
HCT116,
ATCC
,Cat#
CCL-247EMT
HCT-15
,
ATCC
,Cat#
CCL-225
,, "Chemicals, peptides, and recombinant proteins","Chemicals, peptides, and recombinant proteins","Chemicals,
(8)
Identification of HLA class II-restricted T cell receptors against shared PIK3CA mutations in patients with epithelial cancers
Cancer Immunol Immunother
December 18, 2025
S. M. Rafiqul Islam, Samantha Seitter, Maria Parkhurst, Frank J. Lowery, Miaki Fukuhara, Sanghyun P. Kim, Noam Levin, Jared J. Gartner, Satyajit Ray, Todd Prickett,
et al.
(
ATCC
) were cultured in
DMEM
(Gibco), supplemented with 10% FBS (Gibco) without any antibiotics.
HCT-15
(
CCL-225
) cell line (
ATCC
) was cultured in
RPMI 1640
media.
HTB-22
(MCF-7) and
HTB-114
tumor cell lines
(
ATCC
)
(9)
Honokiol Inhibits Colorectal Cancer Cell Growth: Involvement of Hsp27 as a Molecular Target
Current Issues in Molecular Biology
November 5, 2025
Youngbin Kim, Hyeon Du Jang, Da Hyeon An, Hyun Seo Lee, Hong-Gyum Kim, Sun Eun Choi
Agilent Technologies
(#
200523
, Santa Clare, CA, USA). 2.4. Cell Lines and
Cell Culture
CRC cell lines
HCT-15
(
ATCC
CCL-225
),
DLD-1
(
ATCC
CCL-221
), HCT116 (
ATCC
CCL-247
), and
HT-29
(
ATCC
HTB38
) were purchased from the American
(10)
Antiparasitic effect of peptoids against Cryptosporidium parvum
Microbiology (Reading)
October 13, 2025
Bridget Lamont, Bruce Malcolm Russell, Rossarin Suwanarusk, Josefine Eilsø Nielsen, Kristian Sørensen, Deborah Yung, Annelise E. Barron, Daniel Pletzer, Morad-Remy Muhsin-Sharafaldine
#
21600010
)] at 4 °C for no longer than 4 months. HCT-8, a
human
ileocaecal
adenocarcinoma
cell line (
ATCC
#
CCL-225
) used as host cells, was gifted from the Guildford Lab (University of Otago, New Zealand). A library
(11)
Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD
Nature Metabolism
September 19, 2025
Tianshi Feng, Qin Luo, Yanlin Liu, Zeyu Jin, David Skwarchuk, Rumi Lee, Miso Nam, John M. Asara, Daya R. Adye, Philip L. Lorenzi,
et al.
(
ATCC
,
CCL-253
), Colo205 (
ATCC
,
CCL-222
),
SW620
(
ATCC
,
CCL-227
),
SW48
(
ATCC
,
CCL-231
) and HCT15 (
ATCC
,
CCL-225
). The DiFi, GP5D and HT55 cell lines were provided by J. Engelman, and the VACO432 cell line was provided
(12)
Domain-Specific Impacts of Spike Protein Mutations on Infectivity and Antibody Escape in SARS-CoV-2 Omicron BA.1
Journal of Microbiology and Biotechnology
September 16, 2025
Tae-Hun Kim, Sojung Bae, Jinjong Myoung
Republic of Korea) [17, 18, 24, 25]. HCC15-ACE2 cells, a stable HCC15 lung
carcinoma
cell line (
ATCC
,
CCL-225
) expressing the
human
angiotensin-converting enzyme 2 (hACE2) receptor via lentiviral transduction,
(13)
Betulinic Acid ω-Triphenylphosphonium Alkyl Esters: Antiproliferative Activities and In Silico Pharmacokinetic Profiles
Biomedicines
June 24, 2025
Cristian Suárez-Rozas, Claudia Duarte-Salinas, Javier Gajardo-De la Fuente, Paola Salgado-Figueroa, Julio Salas-Norambuena, Bruce K. Cassels, Cristina Theoduloz, José A. Jara, Sebastián Fuentes-Retamal, Paola R. Campodónico,
et al.
bicarbonate. Promyelocytic
leukemia
HL-60
(
ATCC
®
CCL-240
™), colorectal
adenocarcinoma
HCT-15
(
ATCC
®
CCL-225
™), metastatic colorectal COLO205 (
ATCC
®
CCL-222
™), and
breast cancer
AU565 (
ATCC
®
CRL-2351
™, ER−-HER2/neu+)
(14)
Cytoplasmic physicochemical factors drive malignant transformation by adapting bioenergetic settings
Biochem Biophys Rep
June 7, 2025
Tattym E. Shaiken
methods 2.1 Cell line,
cell culture
,
cell fractionation
, and chemicals
Colorectal carcinoma
HCT-15
(
CCL-225
) cells, purchased from
ATCC
(Manassas, VA 20110, USA), were grown in an incubator under humidified conditions
(15)
5'-Guanidino Xylofuranosyl Nucleosides as Novel Types of 5'-Functionalized Nucleosides with Biological Potential
Pharmaceuticals (Basel)
May 16, 2025
Jennifer Szilagyi, Tânia Moreira, Rafael Santana Nunes, Joana Silva, Celso Alves, Alice Martins, Rebeca Alvariño, Niels V. Heise, René Csuk, Nuno M. Xavier
information. Breast
adenocarcinoma
cells (MCF-7; DSMZ: ACC 115),
colon adenocarcinoma
cells (HTC-15; DSMZ:
CCL-225
), and
prostate
cells (
DU-145
;
ATCC
: HRB-81) were cultured in
RPMI 1640 medium
.
Hepatocyte
cells (
FL83B
;
(16)
Targeting the HER2-ELF3-KRAS axis: a novel therapeutic strategy for KRASG13D colorectal cancer
Mol Cancer
May 9, 2025
Soo-Yeon Hwang, Yoojeong Seo, Seojeong Park, Seul-Ah Kim, Inhye Moon, Yi Liu, Seojeong Kim, Eun Seon Pak, Sehyun Jung, Hyeyoon Kim,
et al.
embryonic cell line (
ATCC
CRL-3216
), and the
colon cancer
cell lines Caco-2 (
ATCC
HTB-37
), HCT15 (
ATCC
CCL-225
), HCT8 (HRT18;
ATCC
CCL-244
),
LoVo
(
CCL-229
), and HCT116 (
ATCC
CCL-247
) were purchased from the Korean
(17)
SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response
Cell Reports
April 22, 2025
Nurul Khalida Ibrahim, Sabine Schreek, Buesra Cinar, Anna Sophie Stasche, Su Hyun Lee, Andre Zeug, Tim Dolgner, Julia Niessen, Evgeni Ponimaskin, Halyna Shcherbata,
et al.
cells,DSMZ,Cat#ACC-362 KOPTK1 cells,ATCC,Cat# CVCL_4965
SW480
cells,
ATCC
,Cat#
CCL-228
HCT-15 cells,
ATCC
,Cat#
CCL-225
CCD841 cells,
ATCC
,Cat#
CRL-1790
HEK293T cells,
ATCC
,Cat#
CRL-3216
Oligonucleotides,Oligonucleotides,Oligonucleotides See
(18)
Inducing Targeted, Caspase-Independent Apoptosis with New Chimeric Proteins for Treatment of Solid Cancers
Cancers (Basel)
March 31, 2025
Orly Melloul, Samar Zabit, Michal Lichtenstein, Deborah Duran, Myriam Grunewald, Haya Lorberboum-Galski
(
ATCC
-
CRL-1740
), Colo205 (ATCC-CCL-22), Colo320 (
ATCC
-
CCL-220
),
SW48
(
ATCC
-
CCL-231
), and HCT115 (
ATCC
-
CCL-225
)
colon adenocarcinoma
cells were grown in
RPMI 1640 medium
(L0501, Biowest, Nuaille, France) supplemented
(19)
Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer
Frontiers in Genetics
March 28, 2025
Ajay Kumar Saw, Ayush Madhok, Anupam Bhattacharya, Soumyadeep Nandi, Sanjeev Galande
colon cancer
lines used including DLD1 (
ATCC
,
CCL-221
)
COLO-205
(
ATCC
,
CCL-222
) and HCT-115 (
ATCC
,
CCL-225
). FHC (fetal
human
colon) and
hESC
(
human embryonic stem cells
) were used as control cell lines, while
(20)
Anticancer Properties Against Select Cancer Cell Lines and Metabolomics Analysis of Tender Coconut Water
Anti-Cancer Agents in Medicinal Chemistry
March 28, 2025
Jaganathan Lakshmanan, Vaitheesh L. Jaganathan, Boachun Zhang, Grace Werner, Tyler S. Allen, David J. Schultz, Carolyn M. Klinge, Brian G. Harbrecht
batches of pooled TCW. 2.3.
Cell Culture
HepG2 (
ATCC
#
HB-8065
), Hep3B (
ATCC
#
HB-8064
),
HCT-15
(
ATCC
#
CCL-225
),
MDA-MB-231
(
ATCC
#
CRM-HTB-26
), MDA-MD-468 (
ATCC
#
HTB-132
), T47D (
ATCC
#
HTB-13
), MCF-7 (
ATCC
#
HTB-22
)
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Reviews
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HCT-15 from ATCC
Supplier Page
View Company Product Page
$431.00
Product Specs
Company Info
Citations
Reviews
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