MESO QuickPlex SQ 120MM from Meso Scale Discovery

Product Specs
ItemMESO QuickPlex SQ 120MM
CompanyMeso Scale Discovery
Price Inquire
Catalog NumberAI1AA-0
DetectionThe MESO QuickPlex® SQ 120MM is MSD's most versatile instrument. This compact system has been engineered for reliability, ease of use, and low cost of ownership. The combination of rapid read times and the ability to perform multiple, simultaneous tests on a single sample increases productivity, saves sample, and delivers results quickly.
ApplicationsSingle and multiplex assays
Plate FormatsMSD 96-well QuickPlex and QuickPlex Ultra™ plates
DetectorElectrochemiluminescence (ECL)

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Meso Scale Discovery

1601 Research Boulevard

Rockville, Maryland 20850-3173

United States

Phone: 1-240-314-2600
Fax: 1-240-632-2219

Email: customerservice@mesoscale.com

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Website: www.mesoscale.com

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(1) Sema3E‐plexinD1 Axis Is a Modulator of Foxp3+ Regulatory T‐Cells in House Dust Mite Model of AsthmaFASEB JJuly 20, 2026Mojdeh Matloubi, Chukwunonso Onyilagha, Lianyu Shan, Sujata Basu, Andrew J. Halayko, Mohamed Almiski, Abdelilah S. GounniCat#K15069M‐1) in BALF supernatants according to the manufacturer's instructions. Plates were read by the MESO QuickPlex SQ 120MM machine (MSD, Rockville, Maryland, US). 2.12 Measurement of Immunoglobulins in Serum Cardiac blood

(2) Adults with Obesity and Hyperglycemia have Higher Arachidonic and Docosahexaenoic Acid in Subcutaneous Adipose TissueJournal of Lipid ResearchJuly 17, 2026Sabrina Ziai, Mihir Parikh, Narjes Mosavari, Ruxandra D. Rotarescu, Chuck T. Chen, Richard P. Bazinet, André Tchernof, Anthony J. Hanley, Adam H. Metherel, Jacqueline L. BeaudryHuman Insulin Assay (Cat#. K151S5-Series, LOT#. K0082754, Meso Scale Discovery®, Rockville, MD, USA). MESO QuickPlex SQ 120MM was used to read the plate, and data were analyzed on the Discovery WorkbenchTM 2013 LSR_4_0_13 (Meso

(3) Dual Inhibition of TNF-α and IL-6R mitigates cytokine release syndrome via protection of endothelial integrity and reduction of organ damage in mouse modelsFront ImmunolJuly 10, 2026Hyeyun Won, Eunyoung Park, Yun-Gil Roh, Mincheol Kang, Nari KimElectrochemiluminescence signals were detected and analyzed using an MSD Luminescence Spectrometer (Meso Scale Discovery, AI1AA-0). Additionally, sIL-6R levels were measured in serum samples pooled by groups using the Human IL-6R

(4) Engineered T7 RNA polymerase to improve mRNA capping efficiency and reduce dsRNA generation during in vitro transcriptionMolecular Therapy AdvancesJune 11, 2026Athul Sanjeev, Casey Hannigan, Ryan Garrity, Dhinesh Srinivasan Kamalakkannan, Victoria Clendaniel, Manini Mantri, Zach Glass, Lisa N. Kasiewicz, Jay Leipheimer, Zunera Khan, et al.using antibodies specific to Cas9. The electrochemical luminescence signals were captured using the MESO QuickPlex SQ 120MM instrument and analyzed using the DISCOVERY WORKBENCH 4.0 Analysis Software (MSD). A known concentration

(5) Commensal Dysbiosis Alters Primary Bile Acid Signaling to Drive Mammary Gland Inflammation and Breast Tumor DisseminationCancer ResJune 2, 2026Audrey M. Putelo, Simona Bajgai, Mika K. Poblete, Gabrielle Guido, Mirna Perusina Lanfranca, Qingyi He, Tajbir Raihan, Cara N. Hatzinger, Akshita Mirani, Sree H. Kolli, et al.run in duplicate, tissue lysates at 100 ug protein per well. Analyte concentrations were read on a MESO QuickPlex SQ 120MM using Discovery Workbench (Meso Scale Discovery, v4.0) and calculated from standard curves generated

(6) The Inflammatory Response in the Murine Ovalbumin-Induced Skin Inflammation Model Is Robust Despite Major Gut Microbiota DifferencesClin Transl SciJune 2, 2026Ida Wang Henriksen, Christina Bartholdy, Janne Koch, Denitsa Vladimirova Stefanova, Camilla Hartmann Friis Hansen, Axel Kornerup HansenIL‐10, IL‐13, IL‐17A, IL‐12p70, IL‐31, IL‐1β, eotaxin, TARC, RANTES, MMP‐9, KC/GRO, and TNF‐α on a MESO QuickPlex SQ 120MM instrument with corresponding instructions (Meso Scale Discovery, Rockville, MD, USA). 2.5 Serum IgE

(7) Greek Yogurt Compared with Whey Protein Supplementation in Adolescent Athletes Throughout a Competitive SeasonThe Journal of NutritionJune 1, 2026Madison Bell, Pedro Henrique Narciso, Ethan Miskolczi, Maria I Retsidou, Brian D Roy, Andrea R Josse, Bareket Falk, Panagiota Klentrouand the intra- and interassay %CV <10 and <15, respectively. RANKL analysis was performed using the MESO QuickPlex SQ 120MM instrument with Methodical Mind and DISCOVERY Workbench software (version 4.0, Meso Scale Discovery).

(8) Widespread SARS-CoV-2 Transmission Despite Limited Reported Cases and Clinical Disease: Exploring the Role of Pre-Existing Humoral Immunity to SARS-CoV-2 in Eastern Sierra LeoneImmun Inflamm DisMay 6, 2026Robert J. Samuels, Nell G. Bond, Ibrahim Sumah, Donald S. Grant, Mohamed S. Kamara, Lydia Bazzano, Camilo Fernandez, Rodrigo Borrega, Sruti Chandra, Celia R. Glezer, et al.manufacturer's instructions with attention to recommended best practices. Plates were then read immediately on a MESO QuickPlex SQ 120MM instrument (Meso Scale Diagnostics LLC, Rockville, MD) and antibody concentrations were calculated using

(9) Exosome-like nanoparticles from the Okinawan medicinal plant Talinum fruticosum exhibit subset-specific bioactivities in vitro : Suppression of IL-6 production and reduction of intracellular reactive oxygen speciesBiomedical ReportsApril 17, 2026Yasunari Kageyama, Kazunori Namba, Yuki Akamatsu, Tomoka Ebisui, Koichi Aida, Tsutomu Nakamurasupernatant were measured using the V-PLEX Pro-inflammatory Panel 1 Human Kit (Meso Scale Discovery) and the MESO QuickPlex SQ 120MM (Meso Scale Discovery). Intracellular reactive oxygen species (ROS) assay THP-1 macrophages were pretreated

(10) (Ultra-)inflammation or adaptation? Comparison of different ultramarathon distances and their effect on the immune systemFront ImmunolApril 13, 2026Daniel A Bizjak, Lucas John, Moritz Munk, Roman Bizjak, Jens Witzel, Christoph Siebers, Sebastian V. W. Schulz, Harald Engler, Michael Siebers, Johannes Kirsten, et al.multiplex electrochemilumenscence (ECL) assay (U-plex, Meso Scale Discovery, Rockwell, MD, USA) on a MESO QuickPlex SQ 120MM instrument (Meso Scale Discovery) according to the manufacturers’ protocol. Sensitivity of the assay

(11) Single-dose VSV-Sudan virus vaccine protects from lethal Sudan virus infection within one week: a challenge study in macaques: VSV-SUDV but not VSV-EBOV protects NHPs from Sudan virus diseasebioRxivApril 12, 2026Paige Fletcher, Kyle L. O’Donnell, Friederike Feldmann, Joseph F. Rhoderick, Chad S. Clancy, Cecilia A. Prator, Brian J. Smith, Bronwyn M. Gunn, Heinz Feldmann, Andrea MarziUSA) U-PLEX NHP multiplex assay according to manufacturer’s instructions. Samples were read on the MSD MESO QuickPlex SQ 120MM with Methodical Mind software (v. 1.0.38) and analyzed with MSD Discovery Workbench software (v. 4.0). Statistical

(12) ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte ToxicitybioRxivApril 6, 2026Elena Coccia, Gustavo Morrone Parfitt, Sundas Ijaz, Aisha Sati, Julia Gesner, Andrea Perez Arevalo, Jennifer Strong, Anna Bright, Soha Sohail, Thea Meimoun, et al.with SULFOTAG–labeled secondary antibodies, and electrochemiluminescence signals were acquired using a MESO QuickPlex SQ 120MM reader (Meso Scale Discovery). Statistical Analysis All experiments were performed in at least three

(13) CXCR3 is associated with T-cell-induced heart damage in acute rheumatic feverNature CommunicationsMarch 31, 2026Francis M. Middleton, Reuben McGregor, Natalie Lorenz, Sarah Kilian, Anna E. S. Brooks, Saem Mul Park, Ciara Ramiah, Judith Tresidder, Timothy C. Barnett, Michael Serralha, et al.analysed by use of electrochemiluminescent sandwich immunoassay (Meso Scale Discovery), read on the MESO QuickPlex SQ 120MM, and analysed using Methodical Mind software (https://msd.methodicalmind.com). Serum analytes were quantified

(14) Evaluation of a reference antibody panel for prediction of cytokine release in humanised mouse models in vivoFrontiers in ImmunologyMarch 20, 2026Deepa Rajagopal, Ka Seng Ieong, Ryan Mate, Sandrine Vessillier(Meso Scale Discovery, Maryland, USA) in accordance with manufacturer’s instructions. Plates were read on The MESO QuickPlex SQ 120MM, with Methodical Mind software (Meso Scale Discovery, Maryland, USA). Data analysis was performed using

(15) Similarity of sputum mediator signatures between e-cigarette users and COPD depends on GOLD stage and type of e-cigarette: a pilot studyPLoS OneMarch 9, 2026Elise Hickman, William Dabbs, Heather Wells, R. Graham Barr, Prescott Woodruff, Jill Ohar, Fernando J. Martinez, Russell Bowler, Christopher B. Cooper, Jeffrey L. Curtis, et al.plate. Plates were read on the same instruments (BMG Labtech CLARIOstar for single-plex ELISAs and MESO QuickPlex SQ 120MM for Mesoscale Discovery assays) for each of the two sample sets. Differential cytospin analysis. All

(16) Home-Based Exercise Improves Muscle Oxidative Capacity in Kidney DiseaseKidney International ReportsMarch 1, 2026Gwénaëlle Begue, Armin Ahmadi, Christopher MT. Hayden, Alec Foster, Usman Rehman, Jennifer E. Norman, Chenoa Vargas, Brian J. Bennett, Craig McDonald, T. Alp Ikizler, et al.IL-1β, and IL-10) were assessed in duplicates (pg/ml) in a single multiplex electroluminescence assay (MESO QuickPlex SQ 120MM) using the proinflammatory panel 1 V-Plex kit (K15049D, Meso Scale Discovery, Rockville, MD) and following

(17) Reversing T cell dysfunction in a novel in vitro model of T cell exhaustion reveals differential roles of RASA2Frontiers in ImmunologyFebruary 25, 2026Hilal Saraç, Rachael Nicholson, Rebecca N. Graham, Meera Augustus, Raha Taghavi, Dympna J. Connolly, Lindsay Lim, Sofia LourencoU-plex TGF-β Combo Human (#K15241K-4) according to the manufacturer’s instructions. Plates were read on Meso QuickPlex SQ 120MM instrument. Data analysis was conducted on MSD Discovery Workbench software. Statistical analysis Statistical

(18) Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapyNature MedicineFebruary 12, 2026Aarthi Talla, Joao L. L. C. Azevedo, Muhammad Bilal Latif, Ana B. Enriquez, Gabriela Pacheco Sanchez, Adam N. Pelletier, Saswat Kumar Bal, Sangeeta Kumari, Viviane Schuch, Khader Ghneim, et al.acid, followed by base neutralization to activate the TGF family proteins. Plates were read on the MESO QuickPlex SQ 120MM (MesoScale Discovery) instrument, and cytokine levels were calculated using a standard curve of known

(19) Beyond Rifampin: Evaluating Rifapentine and Rifabutin as Alternative Treatments for Tuberculous MeningitisThe Journal of Infectious DiseasesFebruary 10, 2026Xueyi Chen, Carlos E. Ruiz-Gonzalez, Yuderleys Masias-Leon, Medha Singh, Oscar J. Nino-Meza, Charles A. Peloquin, Dmitri Artemov, Sanjay K. Jainand chemokines were analyzed using the Meso Scale Discovery plate-based assay on Mesoscale Discovery MESO QuickPlex SQ 120MM Multiplex Reader at the Institute for Clinical and Translational Research, Johns Hopkins University.

(20) Early mechanisms of diabetes development in pediatric pancreatitis: A pilot studyJournal of Pediatric Gastroenterology and NutritionFebruary 1, 2026Maria Graciela Parra Parra Villasmil, Melena Bellin, Catherina Pinnaro, Fati Craighead, Gretchen Cress, Aliye Uc, Mark Lowe, James S. Hodges, Katie Larson Larson Odequantitated with a Mesoscale V-PLEX assay, following the manufacturer’s instructions and read with a MESO QuickPlex SQ 120MM plate reader. The lower limits of detection were 0.01 pM, 0.13 pM and 0.043 pg/mL for GLP-1, glucagon,

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MESO QuickPlex SQ 120MM from Meso Scale Discovery

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MESO QuickPlex SQ 120MM from Meso Scale Discovery

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