Description
The Octet® RH16 16-channel instrument provides analytical performance similar to the 8- channel Octet® instruments, but with higher levels of throughput, speed, and flexibility.
The Octet® RH16 GxP Package includes the Octet® RH16 instrument and all the required compliance tools like Octet® CFR Software, desktop computer, LCD monitor, accessory kit, IQOQ Kit, PQ Kits and one-year warranty for complete instrument qualification. These comprehensive compliance tools enable Octet® systems to be easily integrated in analytical development and regulated GxP labs. Multiple applications, including lot release and in-process testing for ligand binding, concentration and impurity analysis (HCP, residual protein A) are increasingly being run on Octet systems. These systems have also become a solution platform for potency analysis of drug-target and drug-Fc receptor(s) (FcγRI, FcγRIIa, FcRIII and FcRn) interactions. For more information, please see GxP applications.
Octet systems have been developed to operate in a regulated environment, with available installation and operational qualification services, maintenance support and 21 CFR Part 11-compliant software tools. The high detection sensitivity and impressive throughput of Octet® RH16 system has made it a favorite for small molecule library screening and analysis of large cross-competition binding matrices.
Key Features - High sensitivity detection
- 16-well simultaneous sampling
- 384-well and 96-well formats
- Two plate locations maximize throughput and improve workflow
- Automation friendliness allows multiple-plate assays in one run
- Biosensor re-racking allows maximum flexibility and operational cost savings
- Advanced software offers greater versatility in experimental design and data analysis
Kinetic analysis including association and dissociation of biomolecules can be performed on up to 384 samples in one 384-well microplate. The biosensor, sample and reagent trays can be transferred to and from the Octet® instrument by robots. Target ligands can be batch immobilized onto biosensors and returned to the biosensor tray for re-use in future experiments, thus extending the number of uses for each biosensor, preserving valuable ligand, and maximizing flexibility in experimental design.