Indirubin from Enzo Life Sciences, Inc.

Description

Inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) and of GSK-3β (IC50=600nM). Inhibits inflammatory reaction in delayed-type hypersensitivity in mice. Ligand of human aryl hydrocarbon receptor. Exhibits anti-cancer activity

Product Specs
ItemIndirubin
CompanyEnzo Life Sciences, Inc.
Price $56.00Supplier Page View Company Product Page
Catalog NumberALX-270-361-M001
Quantity1 mg
Purity≥97% (HPLC)
Sample TypePurple powder
Molecular Weight262.3
Source/Expression SystemSynthetic
FormulaC₁₆H₁₀N₂O₂
TypeBiochemical
Molecule NameIndirubin

Specifications/Features

Inhibitor of CDK and GSK

Ki, IC, EC, or working concentration: cyclin-dependent kinases (CDK1/cyclin B (IC50=10µM), CDK2/cyclin A (IC50=2.2µM), CDK2/cyclin E (IC50=7.5µM), CDK4/cyclin D1 (IC50=12µM), CDK5/p35 (IC50=5.5µM)) [1] and of GSK-3beta (IC50=600nM)

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