22Rv1 from ATCC

Product Specs
Item22Rv1
CompanyATCC
Price $0.00Supplier Page View Company Product Page
Catalog NumberCRL-2505
TypeCell Biology
SpeciesHomo sapiens
TissueProstate
DiseaseCarcinoma
Cell Line22Rv1
Validated Species ReactivityHuman (Hu)
Tissue (standardized)Prostate
Cell Typeepithelial cell

Specifications/Features

Post freeze viability ≥ 50%

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Biobank of genetically defined murine prostate cancer tumoroids uncovers oncogenic pathways and drug vulnerabilities driven by PTEN-lossCell Reports MethodsApril 20, 2026Jessica Kalla, Thomas Dillinger, Zlata Pavlovicova, Reema Jacob, Emine Atas, Katarina Mišura, Anil Baskan, Kristina Draganić, Andreas Tiefenbacher, Tanja Limberger, et al.lines,Experimental models: Cell lines,Experimental models: Cell lines ,, Human 22RV1 primary PCa cell line,ATCC,CRL-2505; RRID:CVCL_1045 Human LNCaP metastatic PCa cell line,ATCC,CRL-1740; RRID:CVCL_A4BQ Human DU145 metastatic

(2) Context-dependent translation inhibition as a cancer therapeutic modalityNature communicationsFebruary 24, 2026Diamond PD, Sauer PV, Holm M, Swanson-Swett CJ, Ferguson L, Bratset NM, Wienker GW, Sim JS, Adams HK, Kenner L, et al.used in this study were purchased from ATCC and cultured using recommended protocols: 22Rv1 (ATCC, CRL-2505), MCF-7 (ATCC, HTB-22), HCC−1143 (ATCC, CRL-2321), LS411N (ATCC, CRL-2159), and MRC5 (ATCC, CCL−171). Western blot

(3) A panel of four autoantibodies to tumour-associated antigens in patients with prostate cancer and its potential for multi-cancer detectionBritish Journal of CancerFebruary 8, 2026Cuipeng Qiu, Xiao Wang, Giulio Francia, Carlos A. Casiano, Jian-Ying ZhangInstitutional Review Boards of UTEP and LLU. Three human PCa cell lines PC3 (CRL-1435, ATCC), 22Rv1 (CRL-2505, ATCC), and LNCaP (CRL-1740, ATCC) were cultured in RPMI-1640 Medium (GIBCO, Life Technologies, USA)

(4) PRDM16 Regulates Prostate Cancer Cell Dormancy and Prevents Bone Metastatic OutgrowthCancer ResearchFebruary 2, 2026Mostafa M. Nasr, Bishoy Wadie, Tao Li, Jeremy S. Frieling, Haley du Bois, Ryan T. Bishop, Marilena Tauro, Baasil Malik, Karl J. Nyman, Conor C. LynchData analysis was performed in an unblinded manner. Cell lines, reagents, and animals The 22Rv1 (CRL-2505, RRID: CVCL_1045) cell line was purchased from ATCC. RM1 (ATCC, cat. #CRL-3310, RRID: CVCL_B459) and

(5) DHODH links mitochondrial bioenergetics, one-carbon metabolism, and DNA repair to sustain aggressive prostate adenocarcinomaCell Communication and SignalingJanuary 29, 2026Saiswaroop Rajaratnam, Danthasinghe Waduge Badrajee Piyarathna, Ranjit K. Mehta, Venugopalareddy Mekala, Jun Hyoung Park, Uttam Rasaily, Vani Venkatappa, Karthik Reddy Kami Reddy, Vasanta Putluri, Kaveri Goel, et al.provided by Dr. Nora Navone (MD Anderson Cancer Center), and the 22RV1 cell line was purchased from ATCC (CRL-2505). Short Tandem Repeat (STR) profiling was performed on all cell lines at the MD Anderson Cytogenetics

(6) Complexoform-restricted covalent TRMT112 ligands that allosterically agonize METTL5Nature Chemical BiologyJanuary 8, 2026F. Wieland Goetzke, Steffen M. Bernard, Cheng-Wei Ju, Jonathan Pollock, Kristen E. DeMeester, Jacob Gross, Gabriel M. Simon, Chuan He, Bruno Melillo, Benjamin F. Cravattwith 10% FBS, 2 mM l-glutamine, penicillin (100 U per ml) and streptomycin (100 μg ml−1). 22Rv1 (ATCC, CRL-2505) cells were grown in RPMI medium supplemented with 10% FBS, 2 mM l-alanyl-l-glutamine (GlutaMAX), penicillin

(7) Casticin inhibits AKR1C3 and enhances abiraterone efficacy in castration-resistant prostate cancerJournal of Natural MedicinesJanuary 1, 2026Kamil Piska, Michał Zubek, Adam Bucki, Maria Świtalska, Paulina Koczurkiewicz-Adamczyk, Benedykt Władyka, Marcin Kołaczkowski, Elżbieta Pękalaactivity. No enzyme-independent NADPH/substrate reaction was observed. Cell culture 22Rv1 (ATCC, CRL-2505) and LNCaP (ECACC, CRL 1740) prostate cancer cell lines and PNT-2 (Sigma–Aldrich cat. No. 95012613)

(8) Novel Mixed Cancer-Cell Models Designed to Capture Inter-Patient Tumor Heterogeneity for Accurate Evaluation of Drug CombinationsInternational Journal of Molecular SciencesDecember 30, 2025Sampreeti Jena, Daniel C. Kim, Adam M. Lee, Weijie Zhang, Kevin Zhan, Radwa M. Elmorsi, Yingming Li, Scott M. Dehm, R. Stephanie Huangthe recurrent CWR22 human xenograft [25]. DU145 (Cat. # HTB-81, RRID: CVCL_0105) and 22RV1 (Cat. # CRL-2505, RRID: CVCL_1045) prostate cancer cell-lines were obtained from the American Type Culture Center (ATCC,

(9) Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate canceriScienceDecember 19, 2025Daniel Westaby, Juan M. Jiménez-Vacas, Ines Figueiredo, Jonathan Welti, Bora Gurel, Denisa Bogdan, Lorenzo Buroni, Antje J. Neeb, Jan Rekowski, Ana Padilha, et al.lines,Experimental models: Cell lines ,, C4-2,ATCC,CRL-3314 LNCaP,ATCC,CRL-1740 VCaP,ATCC,CRL-2876 22Rv1,ATCC,CRL-2505 LNCaP95,"Dr Meeker/Dr Luo (Johns Hopkins University, Baltimore, Maryland, USA)",N/A PC3,ATCC,CRL-1345 DU145,ATCC,HTB-81 ,, Experimental models

(10) PROCA11 early activation fuels prostate cancer neuroendocrine traits by regulating cell survival and migrationiScienceDecember 19, 2025Rocco Cipolla, Marc Gabriel, Ugo Szachnowski, Zhimin Wang, Martina Romani, Giorgia Ianese Regin, Micaela Piemontese, Virginie Firlej, Marina Pinskaya, Antonin Morillon(Life Technologies) supplemented with 10% FBS. The 22Rv1 and PC3 cell lines were purchased from ATCC (CRL-2505, CRL-1435) and cultured in 10% FBS complemented RPMI 1640 media. Cells were systematically tested and

(11) Menin-driven mTOR signaling sustains taxane resistance in CRPC and reveals a targetable vulnerability for combination therapyCell Communication and SignalingDecember 18, 2025Ipek Bulut, Buse Cevatemre, Neslihan Yuksel-Catal, Hamzah Syed, Tamer Onder, Ceyda Acilantarget. Materials and methods Generation of resistant cells The Du145 and 22Rv1 cells (ATCC, #HTB-81; ATCC, #CRL-2505) were grown in RPMI-1640 media (Gibco, #11875093) supplemented with 10% FBS (Biowest, S1810) and 1%

(12) Extracellular Domain Shedding of TROP2 Activates EGFR Signaling to Drive Prostate Cancer MetastasisCancer researchDecember 1, 2025Liu S, Hsu EC, Aslan M, Garcia-Marques F, Shen M, Hartono AB, Solano F, Le K, Hwang H, Lee CS, et al.Stanford University (IRB: 6528). Cell Culture DU145 (ATCC- HTB-81, RRID: CVCL_0105), 22Rv1 (ATCC- CRL-2505, RRID: CVCL_1045), LNCaP (ATCC- CRL-1740, RRID: CVCL_0395), C4–2 (ATCC- CRL-3314, RRID: CVCL_4782),

(13) Optimised dissociation and multimodal profiling of prostate cancer stroma reveal fibromuscular cell heterogeneity with clinical correlatesFrontiers in Cell and Developmental BiologyNovember 25, 2025Elisabeth Damisch, Elena Brunner, Lukas Nommensen, Lucy Neumann, Georgios Fotakis, Zlatko Trajanoski, Sieghart Sopper, Georg Schäfer, Martin Puhr, Isabel Heidegger, et al.culture The 22Rv1 prostate cancer cell line was obtained from the American Type Culture Collection (ATCC Nr. CRL-2505; ATCC; Rockville, MD), STR validated and maintained according to the distributor’s instructions. Human

(14) Effect of TGF-β mediated phenotypic changes on prostate cancer cell anoikis responseOncogeneNovember 22, 2025Prerna R. Nepali, Edgar Gonzalez-Kozlova, Maitri Anegondi, Navneet Dogra, Maddison Archer, Goutam Chakraborty, Ashutosh K. Tewari, Benjamin D. Hopkins, Natasha Kyprianoutherapeutic resistance. Materials and methods Cell lines Human prostate cancer cell lines 22RV1 (CRPC) (CRL-2505) (RRID:CVCL_1045) and LNCaP (androgen sensitive) (CRL-1740) (RRID:CVCL_1379) were obtained from ATCC,

(15) A Hybrid compound H93 treats prostate cancer by directly binding UHRF1 and promoting protein dimerizationCommunications ChemistryNovember 18, 2025Yuxin Fu, Longying Jiang, Guojian Xie, Yuchong Peng, Yongming Fu, Qianling Zhu, Youhong Liu, Guilong Zhao, Xueke Liu, Yongbo Peng, et al.Bethesda, MA, USA), VCaP (PCa, Cat#CRL-2876, ATCC), PC3 (PCa, Cat#CRL-1435, ATCC), CWR22Rv1 (PCa, Cat#CRL-2505, ATCC), C4-2 (PCa, Cat#CRL-3314, ATCC), LNCaP (PCa, Cat#CRL-1740, ATCC), HUVEC (human umbilical venous

(16) FOXD1, a hypoxia-related gene, accelerates prostate cancer cell growth by increasing glycolysis under hypoxia conditionsBMC BiotechnologyNovember 10, 2025Jing Gao, Shuang Wu(Gibco, Grand Island, NY, USA). Two human prostate cancer cell lines PC-3 (CRL-1435; ATCC) and 22Rv1 (CRL-2505; ATCC) were maintained in F-12 K (30-2004; ATCC) and RPMI-1640 medium (30-2001; ATCC), respectively.

(17) Targeting endoplasmic reticulum stress and nitroso-redox imbalance in neuroendocrine prostate cancer: the therapeutic role of nitric oxideCell Death DiscoveryNovember 6, 2025Fakiha Firdaus, Osmel Companioni Napoles, Raul Ariel Dulce, Anusha Edupuganti, Surinder Kumar, Khushi Shah, Salih Salihoglu, Derek J. Van Booven, Richard Gasca, David B. Lombard, et al.the strength of the association between gene expression and survival outcomes. Cell culture PC3 (CRL-2505), DU145 (CRL-1740) and H660 (CRL-5813) were purchased from ATCC. PC3 cells (AR-; NEPC-like) were maintained

(18) Caloric Restriction Enhances the Efficacy of Anti-Androgen Therapy in Prostate Cancer by Inhibiting Androgen Receptor TranslationCancer ResearchNovember 3, 2025Ricardo A. Cordova, May Elbanna, Christopher Rupert, Sabrina A. Orsi, Noah R. Sommers, Angela J. Klunk, Li Shen, Jagannath Misra, Jocelyne N. Hanquier, Maria Tsompana, et al.qRT-PCR, and were used at low passage for all experiments. CW22Rv1 (referred to as 22Rv1, ATCC Cat. #CRL-2505, RRID:CVCL_1045) and HEK-293 (ATCC Cat. #CRL-1573, RRID:CVCL_0045) cells were purchased from the American

(19) Collagen-binding IL-12-armoured STEAP1 CAR-T cells reduce toxicity and treat prostate cancer in mouse modelsNature Biomedical EngineeringOctober 23, 2025Koichi Sasaki, Vipul Bhatia, Yuta Asano, Jakob Bakhtiari, Pooja Kaur, Chuyi Wang, Takumi Matsuo, Olivier Dubois, Po-Chuan Chiu, Donny Gun, et al.translation. Methods Cell lines HEK293T (CRL-3216), RM9 (CRL-3312), MyC-CaP (CRL-3255), 22Rv1 (CRL-2505) and Jurkat (TIB-152) cells were obtained from ATCC. HEK293T, RM9 and MyC-CaP cells were maintained

(20) ALKBH5-IGF2BP2 axis mediates prostate cancer progression and docetaxel resistance via m6A-stabilized CLSPN RNAiScienceOctober 17, 2025Yutong Chen, Yang Li, Zongzhu Liang, Zhao Yang, Haotian Ren, Wanqing Wei, Yuanjie Niu, Zhiqun Shanglines,Experimental models: Cell lines ,, Human:LNcap,ATCC,CRL-1740 Human:C4-2,ATCC,CRL-3314 Human:22RV1,ATCC,CRL-2505 Human:PC3,ATCC,CRL-1435 Human:DU145,ATCC,HTB-81 ,, Experimental models: Organisms/strains,Experimental models

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22Rv1 from ATCC

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