Description
Unlock the future with multiple biotherapeutic assays on one platform
The quality assessment of your biopharmaceuticals deserves the best. Using capillary electrophoresis (CE) on the PA800 Plus system lets you challenge the status quo and break through analytical boundaries.
Ultra-high quality separation day in and day out with intuitive kit-based applications for capillary capillary electrophoresis sodium dodecyl sulfate (CE-SDS), capillary gel electrophoresis (CGE), capillary isoelectric focusing (cIEF) and capillary zone electrophoresis (CZE) will help you understand your biotherapeutics and vaccines better to advance them with confidence.
The PA 800 Plus system can help you with:
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Monoclonal antibodies (mAbs) and mAb variants
- Charge heterogeneity (cIEF)
- Purity of mAbs and mAb variants (CE-SDS)
- N-linked gylcan analysis
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In vitro transcribed RNA (IVT RNA)
- Purity and integrity of mRNA and other IVT RNA (CGE)
- Purity and size of critical starting material (CGE)
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Viral vectors
- Capsid protein purity and ratios (CE-SDS)
- Virus genome integrity (CGE)
- Empty-full capsid ratio (CGE and CE-SDS)
- Purity of critical starting material (CGE)
- Residual host cell DNA (CGE)
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Gene editing
- Purity of guide RNA (CGE)
- Purity and integrity of Cas9 mRNA (CGE)
Key features
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Data quality
Achieve highest resolution with unmatched reproducibility using QC-trusted technology, including precise capillary temperature control.
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Flexibility
Gain valuable insights into quality attributes of your biopharmaceuticals with intuitive kit-based assays including CE-SDS, CGE, cIEF, andCZE.
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Sensitivity
Rest assured when sensitivity needs change. Switch between UV and laser-induced-fluorescence (LIF) detection within minutes.
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Portability matters
Confidently transfer methods from lab to lab or between CE systems from SCIEX.
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Compatibility and QC
Meet data management needs with compatibility with the Empower Chromatography Data System (CDS) from Waters and the Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) as well as Windows10. Rely on technology trusted by US Pharmacopeia, such as the USP General Chapter 129.