DAPI from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDAPI
CompanySanta Cruz Biotechnology, Inc.
Price $108.00Supplier Page View Company Product Page
Catalog Numbersc-3598
Quantity10 mg
TypeBiochemical Reagents
Molecular Weight350.24

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Neuroprotective Effects of Strength Training on Behavioral Deficit, Oxidative Damage, Astrogliosis, and Neuronal Death in a Bipolar Disorder ModelJ NeurochemMarch 6, 2026Luan Machado Maidana, Jozyê Milena da Silva Guerra, Adson Souza-Pereira, Mustafa Munir Mustafa Dahleh, Douglas Buchmann Godinho, Marina Prigol, Luiz Fernando Freire Royes, Leonardo Magno Rambocontaining 0.01% FJC (MilliporeSigma; cat. no. AG325) and 0.01% DAPI (Santa Cruz Biotechnology; cat. no. sc‐3598) in 0.1% acetic acid. After staining, slides were rinsed with distilled water, cleared in xylene for

(2) Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitinationJournal of Translational MedicineFebruary 26, 2026Liu Yunxin, Xian Xirui, Zhu Xinyi, Wang Chenjing, Zhang Ting, Fang Kanghui, Yu Haixia, Chang Zude, Huang Wan, Zhu Yubing, et al.with an HRP-labeled secondary antibody (Proteintech). After the final round of staining, DAPI (Cat#sc-3598, Santa Cruz Biotechnology, Texas, USA) solution was added. Photomicrographs were obtained via a light

(3) Submedius thalamic inputs shape the presynaptic architecture of layer 5 orbitofrontal cortex in miceiScienceFebruary 20, 2026Gen-ichi Tasaka, Mitsue Hagihara, Haruna Kobayashi, Miho Kihara, Takaya Abe, Kazunari Miyamichior goat anti-rat IgG Cy3, Jackson ImmunoResearch); and 15 min in 2.5 μg/mL of DAPI (Santa Cruz, Cat #sc-3598) in PBS. Sections were mounted on slides and cover-slipped with mounting medium (Fluoromount; Diagnostic

(4) Bispecific T cell engagers for treatment-refractory autoimmune connective tissue diseasesNature MedicineFebruary 19, 2026Christina Düsing, Andrea-Hermina Györfi, Ayla Nadja Stütz, Laura-Marie Lahu, Franca Sophie Deicher, Yi-Nan Li, Peter-Martin Bruch, Alexandru-Emil Matei, Alexandru Micu, Tim Filla, et al.were performed with anti-CD19 (302202, 1:50; BioLegend) antibodies. Nuclei were stained with DAPI (sc-3598, 1:800; Santa Cruz Biotechnology). Stainings of skin paraffin sections were performed with the anti-BCMA

(5) ZIP8 loss impairs macrophage-mediated phagolysosomal removal of bacteria and is overcome by butyrate supplementationCommunications BiologyJanuary 12, 2026Deandra R. Smith, Sabah Haq, Meng Niu, Sunayana Malla, Rajib Saha, Ashley Peer, Piero Bianco, Svetlana Romanova, Derrick R. Samuelson, Daren L. Knoellthen washed. Cells were resuspended in PB staining buffer, and nuclei were stained with DAPI (cat# sc-3598, Santa Cruz Biotechnologies). Samples were then analyzed using an Amnis FlowSight Imaging Flow Cytometer

(6) Neuroprotective Effects of N-Acetylcysteine-Amide (AD4) in a Survival Mouse Model of Paraoxon Intoxication: Targeting Oxidative Stress, Neuroinflammation and Memory ImpairmentsAntioxidants (Basel)December 6, 2025Edurne Urquizu, Marine Cuiller, Georgia Papadopoulou, David Pubill, Demetrio Raldúa, Jordi Camarasa, Elena Escubedo, Raul López-Arnauantibody for 1 h at room temperature. Slices were washed afterwards and incubated for 5 min with DAPI (sc-3598, Santa Cruz Biotechnology, Dallas TX, USA; 1.5 μg/mL) for nuclei staining. Slices were finally washed

(7) Fusobacterium nucleatum drives gastric cancer metastasis via Gbp-CypA-NF-κB-mediated CXCL8 crosstalk between tumor cells and mast cellsCell Communication and SignalingNovember 28, 2025Xinyi Yang, Tingting Ning, Wanru Zhang, Songyuan Hou, Jiayi Su, Wenkun Li, Jing Wu594-conjugated secondary antibodies were applied for 1 h at room temperature. Nuclei were stained with DAPI (sc3598, Santa Cruz, USA), and the cells were transfered to a confocal dish or slide for observation using a

(8) Altered thrombopoiesis in spontaneously hypertensive ratsScientific ReportsNovember 18, 2025Isaac Rojo, Diana Millán-Aldaco, Ruth Rincón-Heredia, Ivette Martínez-Vieyra, Victor Rosales-García, Gamaliel Aztatzi-Aguilar, Nury Pérez-Hernández, Arturo Hernández-Cruz, Doris Cerecedoantibodies. For nuclei staining, sections were incubated with DAPI (Santa Cruz Biotechnology, cat: sc-3598) or Hoechst 3334 (Sigma-Aldrich, cat: H3570) at 0.2% dilution for 30 min at room temperature. All images

(9) Repeated alcohol drinking in mice is associated with bidirectional alterations in corticostriatal coherenceNeuropharmacologyOctober 1, 2025Cherish E. Ardinger, Mitchell D. Morningstar, Christopher C. Lapish, David N. Linsenbardt(30 %) for cryopreservation. Standard slicing and staining procedures using DAPI (Santa Cruz, Cat No: sc-3598) and GFAP (Fisher, Cat No: NBP105198) were followed to determine electrode placement. Placements can

(10) Monoamine oxidases are mediators of oxidative stress in human varicose Veins: interactions with obesity, inflammation, and angiotensin IIMolecular and Cellular BiochemistrySeptember 29, 2025Sonia Raţiu, Adrian Sturza, Paul S. Muntean, Claudia Borza, Tiberiu Bratu, Danina M. Munteananti-rabbit antibody (Invitrogen, A32731) was applied, and nuclei were counterstained with DAPI (Santa Cruz, SC3598). Slides were examined using a confocal fluorescence microscope (Olympus Fluoview FV1000), and a semi-quantitative

(11) Tissue-Specific Enhancement of Insulin Function and Restoration of Glucose-Stimulated Insulin Secretion by Croton guatemalensis Lotsy and Eryngium cymosum F. DelarochePharmaceuticals (Basel)September 24, 2025Fernanda Artemisa Espinoza-Hernández, Angelina Daniela Moreno-Vargas, Andrea Díaz-Villaseñor, Gerardo Mata-Torres, Jazmín Samario-Román, Adolfo Andrade-CettoFITC-coupled goat anti-rabbit IgG antibody was added (1:200 Aviva Systems, San Diego, CA, USA). DAPI (sc-3598, CAS 28718-90-3, Santa Cruz Biotechnology, Santa Cruz, CA, USA) was used to identify cell nuclei. Mounting

(12) Vitamin D alleviates oxidative stress in varicose veins: a pilot study in obese and non-obese patientsMolecular and Cellular BiochemistryAugust 1, 2025Sonia Rațiu, Mihaela I. Mariș, Adina V. Furdui-Lința, Theia Stanciu-Lelcu, Claudia Borza, Sorin Olariu, Tiberiu Bratu, Adrian Sturza, Danina M. Munteandilution). To visualize cell nuclei, we applied 4′,6-diamidino-2-phenylindole (DAPI) staining (Santa Cruz, SC3598), which allowed for clear identification of nuclear localization within the tissue sections. This protocol

(13) Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBAAdvanced ScienceJuly 21, 2025Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Minfluorescently labeled secondary antibodies at RT for 2 h and mounted with 4′6‐diamidino‐2‐phenylindole (DAPI, sc‐3598, Santa Cruz, USA). For the EVs uptake assays, PKH67 (PKH67GL, Sigma‐Aldrich, USA) was used for the labeling

(14) Orbitofrontal cortex influences dopamine dynamics associated with alloparental behavioral acquisition in female miceSci AdvJuly 4, 2025Gen-Ichi Tasaka, Mitsue Hagihara, Satsuki Irie, Haruna Kobayashi, Kengo Inada, Kenta Kobayashi, Shigeki Kato, Kazuto Kobayashi, Kazunari Miyamichiblocking solution; and 15 min in 4′,6-diamidino-2-phenylindole (DAPI) (2.5 μg/ml; Santa Cruz, catalog no. sc-3598) in PBS. Sections were mounted on slides and coverslipped with mounting media (Fluoro-gold). Expression

(15) Mitochondrial Unfolded Protein Response (mtUPR) Activation Improves Pathological Alterations in Cellular Models of Ethylmalonic EncephalopathyAntioxidants (Basel)June 16, 2025José Manuel Romero-Domínguez, Paula Cilleros-Holgado, David Gómez-Fernández, Rocío Piñero-Pérez, Diana Reche-López, Ana Romero-González, Mónica Álvarez-Córdoba, Alejandra López-Cabrera, Marta Castro De Oliveira, Andrés Rodríguez-Sacristán, et al.paraformaldehyde (PFA) (sc-253236B), oligomycin (sc-203342), antimycin A (sc-202467A), FCCP (sc-203578), DAPI (sc-3598), CPI-613 (sc-482709), thiamine (sc-205859), Biotin (sc-20476), and HEPES (sc-29097) were purchased

(16) Towards Personalized Medicine: Microdevice-Assisted Evaluation of Cancer Stem Cell Dynamics and Treatment ResponseCancers (Basel)June 10, 2025Eduardo Imanol Agüero, Silvia María Gómez López, Ana Belén Peñaherrera-Pazmiño, Matías Tellado, Maximiliano Sebastián Pérez, Betiana Lerner, Denise Belgorosky, Ana María Eijánincubated within the MD for two hours at room temperature. Nuclei were stained with DAPI (1:10,000, sc-3598, Santa Cruz Technologies™, Dallas, TX, USA) for 20 min. Images were captured using a Nikon® Eclipse

(17) Myofibroblast-like Cells and Junctional Complex Development Play a Role in Mouse Pubic Symphysis Remodeling During Pregnancy and PostpartumInt J Mol SciMay 31, 2025Viviane Souza Rosa, Bianca Gazieri Castelucci, Monica Moreira, Paulo Pinto Joazeiro, Sílvio Roberto ConsonniAlexaFluor555 (ThermoFisher, A-31570). The nuclei were stained using 4′,6-diamidino-2-fenilindol (DAPI, SC-3598, Santa Cruz). The sections were mounted with Vectashield Mounting Medium (Vector Labs, Burlingame, CA,

(18) Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington's disease phenotypesMolecular therapy. Methods & clinical developmentMarch 13, 2025Simmons DA, Selvaraj S, Chen T, Cao G, Camelo TS, McHugh TLM, Gonzalez S, Martin RM, Simanauskaite J, Uchida N, et al.following day, cells were washed once with PBS and were incubated in DAPI (Santa Cruz Biotechnology, sc-3598, 1:5000), and secondary antibody diluted in 3% BSA at RT for 45 min. After a wash with PBS, cells were

(19) Disturbed spatial WNT activation - a potential driver of the reticularized skin phenotype in Systemic Sclerosis (SSc)Arthritis & RheumatologyMarch 11, 2025Sara Chenguiti Chenguiti Fakhouri, Honglin Zhu, Yi‐Nan Li, Moritz Ronicke, Aleix Rius Rigau, Clara Dees, Laura Konstantinidis, Ralf Schmid, Alexandru‐Emil Matei, Markus Eckstein, et al.temperature. Next, the sections were counterstained with 4',6‐diamidino‐2‐phenylindole (DAPI) (1:800, #sc‐3598 Santa Cruz Biotechnology). Primary antibodies used were directed against β‐catenin (1:250, #ab2365;

(20) Modulation of comorbid depression of neuropathic pain by dopamine input from VTA to the ventral hippocampusTheranosticsMarch 10, 2025Yuanyuan Ji, Yifan Xiao, Xiaoyan Bai, Junxiang Gu, Teng Ma, Yue Feng, Jian Wang, Yupeng Feng, Tao Chen, Jianghua Lai, et al.(2 mg/kg) 2 h before perfusion. To check the position of the optic and guide cannula, DAPI (1:1000; sc-3598, Santa Cruz, Dallas, TX, USA) was used to counterstain the section for 10 min to show the vHPC profile.

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DAPI Chemicals

DAPI from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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DAPI from Santa Cruz Biotechnology, Inc.

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