U-75302 from Cayman Chemical

Product Specs
ItemU-75302
CompanyCayman Chemical
Price $96.00Supplier Page View Company Product Page
Catalog Number70705
Quantity50 µg
FormatA 500 µg/ml solution in ethanol
Research AreaLipid Biochemistry, Lipoxygenase Pathways
Molecular Weight361.5
Purity≥95%
Storage-20
FormulaC22H35NO3
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Collagen binding adhesin restricts Staphylococcus aureus skin infectionNature CommunicationsJanuary 23, 2026Mohini Bhattacharya, Brady L. Spencer, Jakub M. Kwiecinski, Magdalena Podkowik, Gregory Putzel, Alejandro Pironti, Bo Shopsin, Kelly S. Doran, Alexander R. HorswillImageJ 1.54p software. For BLT-1 inhibitor studies, 10ug U-75302 was diluted in saline (Cayman Chem, 70705) and intradermally injected at or near to the location of infection, 1 day post bacterial inoculation.

(2) LTA4H improves the tumor microenvironment and prevents HCC progression via targeting the HNRNPA1/LTBP1/TGF-β axisCell Reports MedicineMarch 18, 2025Shuai Yang, Xinyao Qiu, Yingcheng Yang, Jing Wu, Shan Wang, Bo Zheng, Jianmin Wu, Tao Zhou, Yangqianwen Zhang, Mixue Bai, et al.including JNK-IN-8 (2.5 μM, Aladdin, J125321), LY255283 (5 μM, MCE, HY-15744) and U-75302 (200 nM, Cayman, 70705), as indicated in the figures. Cells were harvested at the indicated time points, and protein and RNA

(3) A LTB(4)/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous diseaseiScienceApril 19, 2024Haist KC, Gibbings SL, Jacobelli J, Mould KJ, Henson PM, Bratton DL.recombinant proteins","Chemicals, peptides, and recombinant proteins" ,, U75302,Cayman Chemical,Cat #70705 LY255283,Cayman Chemical,Cat #70715 Reparixin L-lysine,R&D Systems,Cat #6957 Boc-MLF,Tocris,Cat #3730 Cyclosporin H

(4) Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuliBiomedicine & PharmacotherapyFebruary 1, 2024Zumer Naeem, Sven Zukunft, Arnaud Huard, Jiong Hu, Bruce D. Hammock, Andreas Weigert, Timo Frömel, Ingrid FlemingCanada) containing solvent (0.3% DMSO), 12,13-EpOME (30 μmol/L/mouse) or U-75302 (10 μg/mouse; Cat# 70705, Cayman, Ann Arbor, MI) immediately after and 6 hours after stripping. Samples were then collected after

(5) Transcellular biosynthesis of leukotriene B(4) orchestrates neutrophil swarming to fungiiScienceOctober 21, 2022Hopke A, Lin T, Scherer AK, Shay AE, Timmer KD, Wilson-Mifsud B, Mansour MK, Serhan CN, Irimia D, Hurley BP.recombinant proteins","Chemicals, peptides, and recombinant proteins" ,, U-75302,Cayman Chemicals,70705; CAS 119477-85-9 SYTOX Green,ThermoFisher Scientific,S7020 Leukotriene B4,Cayman Chemicals,20110;CAS

(6) Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm SignalsCurrent BiologyJuly 20, 2020Hugo Poplimont, Antonios Georgantzoglou, Morgane Boulch, Hazel A. Walker, Caroline Coombs, Foteini Papaleonidopoulou, Milka Sarris11668019 LTB4,Sigma-Aldrich,CAT#L0517-10UG NF279,BIO-TECHNE LTD,CAT#1199 U-75302,Cayman Chemical,CAT#70705 MS-222,Sigma-Aldrich,CAT# E10521-50G 2-APB,Tocris Bioscience,CAT#1224 Methylene blue,Sigma-Aldrich,CAT#

(7) Novel Mechanism of Regulation of the 5-lipoxygenase/leukotriene B4 Pathway by High-Density Lipoprotein in MacrophagesAtherosclerosis SupplementsJune 1, 2018Shigeyasu Tsuda, Masakazu Shinohara, Tatsuro Ishida, Ken-ichi Hiratainhibitor Pitstop 2 (20 µM, ab120687, Abcam) for 30 min or the LTB4 receptor antagonist U75302 (300 nM, 70705, Cayman CHEMICAL). For analysis of the effects of LTB4 on HDL uptake into macrophages, the latter was pretreated

(8) Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophagesScientific ReportsDecember 1, 2017Shigeyasu Tsuda et al.inhibitor Pitstop 2 (20 µM, ab120687, Abcam) for 30 min or the LTB4 receptor antagonist U75302 (300 nM, 70705, Cayman CHEMICAL). For analysis of the effects of LTB4 on HDL uptake into macrophages, the latter was

(9) Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarmingNature Biomedical EngineeringOctober 24, 2017Eduardo Reátegui, Fatemeh Jalali, Aimal H. Khankhel, Elisabeth Wong, Hansang Cho, Jarone Lee, Charles N. Serhan, Jesmond Dalli, Hunter Elliott, Daniel Irimiaand 0.1 M sodium cacodylate were used for neutrophil fixation. U75302 and LY255283 (Catalog number: 70705 and 70715, Cayman Chemicals, Ann Arbor, MI, USA) were used as BLT1 and BLT2 receptor antagonists during

(10) Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in miceNature communicationsJuly 25, 2017Jiang X, Hawkins JS, Lee J, Lizama CO, Bos FL, Zape JP, Ghatpande P, Peng Y, Louie J, Lagna G, et al.treatment of mice with antagonists 5 mg kg−1 zileuton (Cayman #10006967) or 0.5 mg kg−1 U75302 (Cayman #70705) was injected intraperitoneally in pregnant female mice at E9.5 and E10.5. Embryos were harvested on

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U-75302

U-75302

U-75302 from Cayman Chemical

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Cayman Chemical

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U-75302 from Cayman Chemical

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