AG-1478 from Cayman Chemical

Product Specs
ItemAG-1478
CompanyCayman Chemical
Price $25.00Supplier Page View Company Product Page
Catalog Number10010244
Quantity1 mg
FormatA crystalline solid
Molecular Weight315.8
Purity≥98%
TypeInhibitors
Storage-20
FormulaC16H14ClN3O2
OriginUSA
Research AreaCancer, Cell Biology, Cell Signaling, ERK/MAPK Signaling, Growth Factor Receptor Signaling, Growth Factor Receptors

Specifications/Features

Ki, IC, EC, or working concentration: IC50: 3 nM for EGFR
IC50: 9.8 µM for Kv1.5 potassium channels independent of PTK activity
IC50: 5.6 µM for the growth of leiomyoma cell cultures
IC50: 5.7 µM for the growth of myometrium cell cultures

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Phosphoproteomic analysis reveals the diversity of signaling behind E rb B ‐inhibitor‐induced phenotypesThe FEBS JournalJuly 24, 2025Katri Vaparanta, Zejia Song, Iman Farahani, Anne Jokilammi, Johannes Merilahti, Johanna Örling, Noora Virtanen, Pekka Haapaniemi, Cecilia Sahlgren, Klaus Elenius, et al.growth assay Zebrafish embryos of casper line at 2 dpf were treated for 2 days with 10 μm of AG1478 (10010244; Cayman Chemicals, Ann Arbor, MI, USA), 30 μm of lapatinib (S2111; Selleckchem, Houston, TX, USA), 30

(2) A novel group of secretory cells regulates development of the immature intestinal stem cell niche through repression of the main signaling pathways driving proliferation.Developmental BiologyDecember 1, 2019Jianlong Li, Margaret R. Dedloff, Katrina Stevens, Lea Maney, Morgan Prochaska, Cintia F. Hongay, Kenneth N. Wallaceinhibited for 2 hour periods with the cell-permeable EGF kinase inhibitor AG-1478 (Cayman Chemical 10010244) at the previously reported concentration of 3μM solubilized in DMSO (Budi et al., 2008). Control embryos

(3) Decorin antagonizes corneal fibroblast migration via caveolae-mediated endocytosis of epidermal growth factor receptorExperimental eye researchMarch 1, 2019Mohan RR, Tripathi R, Sharma A, Sinha PR, Giuliano EA, Hesemann NP, Chaurasia SS.(100 ng/ml) for 15, 30, or 60 min. The cells were pretreated with AG1478 (Cayman chemicals company 10010244), a specific EGFR kinase inhibitor at 5 μM for 60 min then incubated with EGF or Dcn. hCSF cells were

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AG-1478

AG-1478

AG-1478 from Cayman Chemical

Description

Specifications/Features

Cayman Chemical

Citations (3)

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AG-1478 from Cayman Chemical

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