SB 225002 from Cayman Chemical

Product Specs
ItemSB 225002
CompanyCayman Chemical
Price $169.00Supplier Page View Company Product Page
Catalog Number13336
Research AreaGastric Disease, Immunology & Inflammation, Innate Immunity, Ulcerative Colitis
FormatA crystalline solid
Molecular Weight352.1
Purity≥95%
Storage-20
FormulaC13H10BrN3O4
OriginUSA
TypeInhibitors
Quantity10 mg

Specifications/Features

Ki, IC, EC, or working concentration: IC50: 22 nM IL-8 binding to CXCR2
IC50: 20 nM for neutrophil chemotaxis in response to IL-8 in vitro
IC50: 30 nM for neutrophil margination induced by IL-8 in vivo

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Cerebral Endothelial CXCR2 Promotes Neutrophil Transmigration into Central Nervous System in LPS-Induced Septic EncephalopathyBiomedicinesJuly 11, 2024Wu F, Han Y, Xiong Q, Tang H, Shi J, Yang Q, Li X, Jia H, Qian J, Dong Y, et al.incubator. To block CXCR2 in bEND.3 cells, cells were pretreated for 30 min with the 20 nM SB225002 (13336, Cayman). To block Rho kinase, cells were pretreated for 30 min with 2.5 nM of Y-27632 (10005583, Cayman). 2.3.

(2) Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesityMolecular medicine (Cambridge, Mass.)February 5, 2024Okekawa A, Wada T, Onogi Y, Takeda Y, Miyazawa Y, Sasahara M, Tsuneki H, Sasaoka T.factors, BMDMs were pretreated with 1 μM SB225002, a C-X-C motif chemokine receptor (CXCR)1/2 antagonist (13336, Cayman), 5 μM RS102895, a C–C motif chemokine (CCR)2 antagonist (ab120812, Abcam), or 100 nM C-021,

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SB 225002 from Cayman Chemical

Description

Specifications/Features

Cayman Chemical

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SB 225002 from Cayman Chemical

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