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Protein Biochemistry
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RG108
RG108 from Cayman Chemical
Be the first to write a review!
Citations:
(3)
Supplier Page
Supplier Page from
Cayman Chemical for
RG108
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Description
A non-nucleoside DNA methyltransferase inhibitor (IC50 = 115 nM in vitro) that significantly reduces the methylation of genomic DNA in cells at 10 µM without detectable toxicity
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
RG108
Company
Cayman Chemical
Price
$69.00
Supplier Page
View Company Product Page
Catalog Number
13302
Research Area
Cancer, DNA/RNA Methylation, Epigenetics, Transcription, & Translation, Writers
Format
A crystalline solid
Molecular Weight
334.3
Purity
≥98%
Storage
-20
Formula
C19H14N2O4
Origin
USA
Quantity
5 mg
Specifications/Features
Ki, IC, EC, or working concentration
: IC50: 115 nM
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
A decrease in hepatic microRNA-9 expression impairs gluconeogenesis by targeting FOXO1 in obese mice
Diabetologia
July 1, 2016
Caifeng Yan, Jinfeng Chen, Min Li, Wenying Xuan, Dongming Su, Hui You, Yujie Huang, Nuoqi Chen, Xiubin Liang
also i.p. injected with vehicle (1% [vol./vol.] dimethylsulphoxide [DMSO] in PBS) or
RG108
(
Cayman
,
13302
; 6 mg kg−1 day−1) daily for 5 weeks. The experimenters were not blind to group assignment and outcome assessment.
Real-time PCR
(2)
A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways
Scientific reports
May 9, 2016
Moshfegh C, Aires L, Kisielow M, Vogel V.
(CM) consisting of BGM supplemented with 5 μM Ex527 and 100 μM
RG108
(
Cayman chemical
,
10009798
and
13302
, respectively) for 10 cell passages. The cells were passaged
1:15
–
1:20
every 2 days. Ex527 and
RG108
(3)
Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance
Nature communications
July 3, 2015
Kim AY, Park YJ, Pan X, Shin KC, Kwak SH, Bassas AF, Sallam RM, Park KS, Alfadda AA, Xu A,
et al
.
intraperitoneally injected with vehicle (Veh, 1% DMSO (dimethylsulphoxide) in PBS) or
RG108
(
Cayman
,
13302
; 5.69 mg kg−1 per day) for 32 days. To
measure
fasting glucose and fasting insulin levels, WT or db/db
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RG108 from Cayman Chemical
Supplier Page
View Company Product Page
$69.00
Product Specs
Company Info
Citations
Reviews
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