KN-62 from Cayman Chemical

Product Specs
ItemKN-62
CompanyCayman Chemical
Price $54.00Supplier Page View Company Product Page
Catalog Number13318
Research AreaCalcium Mobilization, Cell Biology, Cell Signaling
FormatA crystalline solid
Molecular Weight721.9
Purity≥98%
Storage-20
FormulaC38H35N5O6S2
OriginCHN
TypeInhibitors
Quantity1 mg

Specifications/Features

Ki, IC, EC, or working concentration: IC50: 900 nM for CamKII
IC50: 15 nM for P2RX7

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) LL-37 and citrullinated-LL-37 enhances oxylipins: citrullination attenuates LL-37-mediated COX-2-dependent chemokine response in human bronchial epithelial cellsRespiratory ResearchJanuary 14, 2026Padmanie Ramotar, Mahadevappa Hemshekhar, Anthony Altieri, Anne M van der Does, Christopher D Pascoe, Neeloffer Mookherjee(DMSO; Fisher Scientific) according to the manufacturer’s instructions. P2X7 inhibitor, KN62 (Cat# 13318) and PGE2 receptors (EP1 − 4) inhibitors, SC-19,220 (EP1; Cat# 14060), PF-04418948 (EP2; Cat# 15016),

(2) Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cellsJ Enzyme Inhib Med ChemAugust 17, 2023Hyeong Jae Kim, Jeong Hee Hongcells were cultured on cover glasses and treated with 100 μM histamine (#H7125, Sigma), 10 μM KN62 (#13318, Cayman, Ann Arbour, MI, USA), and 2 μM bafilomycin (#11038, Cayman) for 24 h. The incubated media were

(3) Lamin-A/C Is Modulated by the Involvement of Histamine-Mediated Calcium/Calmodulin-Dependent Kinase II in Lung Cancer CellsInternational journal of molecular sciencesAugust 13, 2022Kim HJ, Lee PCW, Hong JH.tetrakis-acetoxymethyl ester (#A7076, BAPTA-AM, Sigma), 10 μM Clemastine (#SML0445, Sigma), 10 μM KN-62 (#13318, Cayman, Ann Arbor, MI, USA), 2 μM Rottlerin (#557370, Sigma), 1 mM N-acetyl-l-cysteine (#A9165, NAC,

(4) PSD-95 Serine 73 phosphorylation is not required for induction of NMDA-LTDScientific ReportsDecember 1, 2020Agata Nowacka, Małgorzata Borczyk, Ahmad Salamian, Tomasz Wójtowicz, Jakub Włodarczyk, Kasia Radwanskaactivity To block CaMKII activity in OHC the slices were incubated with 10 µM KN-62 (Cayman chemical, 13318) into the culture medium for 20 min before induction of NMDA-LTD. The NMDA-LTD induction mixture was

(5) RHOA-mediated mechanical force generation through Dectin-1Journal of cell scienceMarch 2, 2020Choraghe RP, Kołodziej T, Buser A, Rajfur Z, Neumann AK.al., 1987), BAPTA-AM (Cayman Chemical, #15551) at 5 µM (Tang et al., 2007), KN-62 (Cayman Chemical, #13318) at 20 µM (Tokumitsu et al., 1990), and blebbistatin (Sigma-Aldrich, #203390) at 12.5 µM, Y-27632 (Sigma-Aldrich,

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KN-62 from Cayman Chemical

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Specifications/Features

Cayman Chemical

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KN-62 from Cayman Chemical

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