FTY720 (S)-Phosphate from Cayman Chemical

Product Specs
ItemFTY720 (S)-Phosphate
CompanyCayman Chemical
Price $600.00Supplier Page View Company Product Page
Catalog Number10006408
Quantity5 mg
FormatA crystalline solid
Molecular Weight387.5
Purity≥98%
Research AreaAdaptive Immunity, Autoimmunity, Glycerophospholipids, Immunology & Inflammation, Immunosuppressants, Innate Immunity, Lipid Biochemistry, Lipid Transport, Multiple Sclerosis, Neurodegenerative Disorders, Neuroscience, Phospholipases, Sphingolipids
Storage-20
FormulaC19H34NO5P
OriginUSA

Specifications/Features

Ki, IC, EC, or working concentration: Ki: 2.1 nM for S1P1
Ki: 5.9 nM for S1P3
Ki: 23 nM for S1P4
Ki: 2.2 nM for S1P5

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) FTY720-P, a Biased S1PR Ligand, Increases Mitochondrial Function through STAT3 Activation in Cardiac CellsInternational journal of molecular sciencesApril 17, 2023Muñoz JP, Sànchez-Fernàndez-de-Landa P, Diarte-Añazco EMG, Zorzano A, Blanco-Vaca F, Julve J.Tween 20 were purchased from Sigma-Aldrich. [U-14C]-glucose was purchased from PerkinElmer. FTY720-P CAY-10006408 was purchased from Cayman, Germany. Hoechst 33342, Rhodamine Phalloidin, MitoSOX Red (M36008), tetramethylrhodamine,

(2) Fingolimod (FTY720), a Sphinogosine-1-Phosphate Receptor Agonist, Mitigates Choroidal Endothelial Proangiogenic Properties and Choroidal NeovascularizationCellsMarch 11, 2022Christine M. Sorenson, Mitra Farnoodian, Shoujian Wang, Yong-Seok Song, Soesiawati R. Darjatmoko, Arthur S. Polans, Nader Sheibaniovernight and then incubated with different concentrations of drug FTY720 (11975), FTY720 (S)-Phosphate (10006408), FTY720 (R)-Phosphate (10006407), and CYM5442 (16925; all from Cayman, Ann Arber, MI, USA), or DMSO

(3) In search of constrained FTY720 and phytosphingosine analogs as dual acting anticancer agents targeting metabolic and epigenetic pathwaysEuropean Journal of Medicinal ChemistryNovember 5, 2018Jean-Baptiste Garsi, Lorenzo Sernissi, Vito Vece, Stephen Hanessian, Alison N. McCracken, Grigor Simitian, Aimee L. Edingerwhich were prepared in DMSO. FTY720 (S)-Phosphate was purchased from Cayman Chemical Company (cat# 10006408) and prepared in DMSO immediately before use. Vorinostat (suberoylanilide hydroxamic acid, SAHA) was

(4) Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphateBioscience ReportsOctober 31, 2018Yuko Mishima, Makoto Kurano, Tamaki Kobayashi, Masako Nishikawa, Ryunosuke Ohkawa, Minoru Tozuka, Yutaka Yatomipreviously [19]. Samples were sonicated in 3 ml of methanol/chloroform (2:1) with FTY720-phosphate (10006408; Cayman Chemical, Ann Arbor, MI) for 30 min Two milliliters of chloroform, 2.1 ml of 1 mM KCl, and 100

(5) Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytesPloS oneJanuary 1, 2017Kurano M, Nishikawa M, Kuma H, Jona M, Yatomi Y.Avanti Polar Lipids) as an internal standard, while for the C17-S1P content, we used FTY720-phosphate (10006408; Cayman Chemical, Ann Arbor, MI). Sphingosine kinase activity assay We measured the sphingosine kinase

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FTY720 (S)-Phosphate from Cayman Chemical

Description

Specifications/Features

Cayman Chemical

Citations (5)

Reviews

FTY720 (S)-Phosphate from Cayman Chemical

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