Calcitriol from Cayman Chemical

Product Specs
ItemCalcitriol
CompanyCayman Chemical
Price $686.00Supplier Page View Company Product Page
Catalog Number71820
Quantity10 mg
Research AreaBone Growth & Remodeling, Cardiovascular System, Cell Biology, Cell Cycle, Chronic Kidney Disease, Cofactors & Vitamins, Cytochrome P450s, Drug Metabolites, Endocrinology & Metabolism, Hormones & Receptors, Immunology & Inflammation, Kidney & Renal Disease, Neuroscience, Toxicology & Xenobiotic Metabolism, Vitamin D Receptor
FormatA crystalline solid
Molecular Weight416.6
Purity≥97%
Storage-20
FormulaC27H44O3
OriginCHN
Source/Expression SystemSynthetic

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Targeting DHODH reveals a metabolic vulnerability in AR-positive and AR-negative prostate cancer cells via pyrimidine synthesis and metabolic crosstalk with the TCA and urea cyclesMolecular MetabolismFebruary 1, 2026Maxime Labroy, Marc-Oliver Paré, Line Berthiaume, Mélissa Thomas, Cynthia Jobin, Alain Veilleux, Martin Pelletier, Frédéric Pouliot, Jean-Yves Masson, Étienne Audet-Walsh(Stemcell Technologies #5711), 10 μM Y27632 dihydrochloride (TOCRIS #1254), 10 μM calcitriol (Cayman Chemical #71820), 500 nM A83-01 (Sigma–Aldrich #SML0788), 10 nM testosterone, 10 nM estradiol (Sigma–Aldrich #E8875),

(2) Immunomodulatory Nanoparticles Enable Combination Therapies To Enhance Disease Prevention and Flare Control in Rheumatoid ArthritisACS Central ScienceSeptember 24, 2025Wade T. Johnson, Elizabeth L. Wilkinson, Neha Iyer, Maksim Dolmat, Miriam Bollmann, Nour Dada, Xiaofu Wei, Shen Yang, Tiffany Zhang, Grace Yoo, et al.PLGA, 2kD PEG SKU: 2794-20K-2000-1g, lot: 2794200204) was purchased from NanoSoft polymers. Calcitriol (71820, lot: 0601887-55) was purchased from Cayman Chemical. Cy5-polyethylene glycol-thiol (2kD, FL078003-2K,

(3) Murine Osteoblast and Osteoclast Co-culture on Demineralized Bone Paper for Bone RemodelingBIO-PROTOCOLJune 5, 2025Seema Amin, Hyejin Yoon, Dong-Hee Choi, Yi-Hao Hsu, Jungwoo Leedetection kit (Sigma, catalog number: 86C) 16. Vitamin D (VD3) (CAYMAN Chemical Company, catalog number: 71820) 17. Prostaglandin E2 (PGE2) (Cayman Chemical Company, catalog number: 14010) 18. 4% Paraformaldehyde

(4) γδ T Are Significantly Impacted by CLL Burden but Only Mildly Influenced by M-MDSCsCancers (Basel)January 14, 2025Michał Zarobkiewicz, Wioleta Kowalska, Agata Szymańska, Natalia Lehman, Bożena Kowalczyk, Waldemar Tomczak, Agnieszka Bojarska-Junakmembrane. Additionally, phospho-vitamin C (Cayman, #16457, conc 100 μg/mL) and/or vitamin D (Cayman, #71820, conc: 10 nM) were added. The co-culture lasted for 48 h. Cytotoxicity was tested on a CLL-derived line

(5) Colon-targeted engineered postbiotics nanoparticles alleviate osteoporosis through the gut-bone axisNature communicationsDecember 30, 2024Yu T, Bai R, Wang Z, Qin Y, Wang J, Wei Y, Zhao R, Nie G, Han B.PVBu and 20 mL of an aqueous solution containing 100 mg calcitriol (Cayman Chemical, USA, catalog No. 71820) and 5% (w/v) Pluronic F-127 (Sigma-Aldrich, USA, catalog No. P2443). The two phases were homogenized

(6) Influence of Vitamin D Receptor Signalling and Vitamin D on Colonic Epithelial Cell Fate Decisions in Ulcerative ColitisJournal of Crohn's and ColitisOctober 15, 2024Lauge Kellermann, Stine Lind Hansen, Grzegorz Maciag, Agnete Marie Granau, Jens Vilstrup Johansen, Joji Marie Teves, Raul Bardini Bressan, Marianne Terndrup Pedersen, Christoffer Soendergaard, Astrid Moeller Baattrup, et al.organoids Intestinal organoid [IO] medium [Supplementary Table S3] was supplemented with 1,25[OH]2D3 [cat. no. 71820, Cayman Chemical, Ann Arbor, MI, USA] or ethanol as a vehicle control. All experiments were performed

(7) Protocol for transducing human primary epithelial prostate cells and patient-derived organoids with high efficiencySTAR ProtocolsSeptember 20, 2024Cynthia Jobin, Mario Harvey, Aurélie Lacouture, Cindy Weidmann, Bertrand Neveu, Frédéric Pouliot, Étienne Audet-WalshY-27632 dihydrochloride,Tocris,1254 Cholera toxin,Calbiochem Biochemicals,227035 A83-01,Sigma-Aldrich,SML0788 Calcitriol,Cayman Chemical,71820 NeuroCult SM1 neuronal supplement (50×),STEMCELL Technologies,05711 Human recombinant R-Spondin-1

(8) Bile acids differentially regulate longitudinal smooth muscle contractility in everted mouse ileumFASEB BioAdvancesJuly 1, 2024Peace N. Dike, Krishnakant G. Soni, Diana S. Chang, Geoffrey A. Preidis,Ursodeoxycholic acid,Cayman Chemicals,15121,Ethanol Receptor agonists,Calcitriol (vitamin D receptor),Cayman Chemicals,71820,DMSO Receptor agonists,Cevimeline (Muscarinic M1/M3 receptor),Cayman Chemicals,17802,PBS Receptor

(9) Differential effects of cholecalciferol and calcitriol on muscle proteolysis and oxidative stress in angiotensin II‐induced C2C12 myotube atrophyPhysiological ReportsApril 16, 2024Muthita Hirunsai, Ratchakrit Srikueafinal concentration) (C9756; Sigma‐Aldrich) and 1,25VD3 (0.1, 1, and 10 nM at the final concentration) (71820; Cayman Chemical, MI, USA) were solubilized with ethanol and applied at Days 5–6 of the differentiation

(10) Immunomodulatory Nanoparticles for Modulating Arthritis FlaresACS NanoJanuary 23, 2024Wade T. Johnson, David A. McBride, Matthew D. Kerr, Anders Nguyen, Martina Zoccheddu, Miriam Bollmann, Xiaofu Wei, Ryan M. Jones, Wei Wang, Mattias N. D. Svensson, et al.Cy5-polyethylene glycol-thiol (2kD, FL078003-2K, lot: 20201217BL05,) was purchased from Biochempeg. Calcitriol (71820, lots: 0601887-33, 0601887-38, 0601887-53, 0601887-69) was purchased from Cayman Chemical. Dimethyl

(11) TGF-β1 stimulation and VDR-dependent activation modulate calcitriol action on skeletal muscle fibroblasts and Smad signalling-associated fibrogenesisSci RepAugust 23, 2023Ratchakrit Srikuea, Muthita Hirunsaiprimary fibroblasts were treated daily with vehicle (0.1% ethanol, final concentration) or calcitriol (71820) (Cayman Chemical, MI, USA) at 1, 10, and 100 nM (final concentrations) for 48 h. Cell proliferation

(12) Urine trace element disorder along with renal function injury in vitamin D deficient diabetic rats and intervention effect of 1α,25-dihydroxyvitamin D3Frontiers in NutritionDecember 6, 2022Dongxia Wang, Ning Wang, Juan Zhou, Gang Luo, Yanyan Li, Wei Yu, Hongxing Tan, Gang Liu, Jun Wang, Liping Haorats. Materials and methods Chemicals 1,25(OH)2D3 (purity ≥ 97%) was obtained from Cayman Chemical (Item No. 71820, USA). Microalbuminuria (MALB) and creatinine assay kits were supplied by Shenzhen Mindray Biomedical

(13) Vasoactive intestinal peptide and cystic fibrosis transmembrane conductance regulator contribute to the transepithelial calcium transport across intestinal epithelium-like Caco-2 monolayerPLoS OneNovember 18, 2022Mayuree Rodrat, Kannikar Wongdee, Jarinthorn Teerapornpuntakit, Jirawan Thongbunchoo, Duangrudee Tanramluk, Ratchaneevan Aeimlapa, Nithipak Thammayon, Natchayaporn Thonapan, Pathnaree Wattano, Narattaphol Charoenphandhuforskolin (catalog no. F6886) were purchased from Sigma. Stock solution of 2.4 mM 1,25(OH)2D3 (catalog no. 71820; Cayman Chemical, MI, USA) was prepared in 9:1 propylene glycol-ethanol before being diluted to 10 μM

(14) Fe3+ opposes the 1,25(OH)2D3-induced calcium transport across intestinal epithelium-like Caco-2 monolayer in the presence or absence of ascorbic acidPLOS ONEAugust 30, 2022Sukpapohn Phummisutthigoon, Kornkamon Lertsuwan, Nattapon Panupinthu, Ratchaneevan Aeimlapa, Jarinthorn Teerapornpuntakit, Wasutorn Chankamngoen, Jirawan Thongbunchoo, Narattaphol Charoenphandhu, Kannikar Wongdeemonolayers were incubated with culture media containing 0, 1, 10 or 100 nM 1,25(OH)2D3 (catalog no. 71820; Cayman Chemical, MI, USA) on both apical and basolateral compartments for 72 h. Thereafter, each Snapwell

(15) Presepsin production in monocyte/macrophage-mediated phagocytosis of neutrophil extracellular trapsScientific reportsApril 8, 2022Ikegame A, Kondo A, Kitaguchi K, Sasa K, Miyoshi M.12-myristate 13-acetate (PMA; Cat, No.P8139; Sigma-Aldrich), 1α, 25-dihydroxyvitamin D3 (VD3; Cat, No.71820; Cayman Chemical Company), May–Grünwald’s stain solution (Cat, No.15053; Mutokagaku, Tokyo, Japan),

(16) Osteogenic Response to Polysaccharide Nanogel Sheets of Human Fibroblasts After Conversion Into Functional Osteoblasts by Direct Phenotypic Cell ReprogrammingFrontiers in Bioengineering and BiotechnologySeptember 3, 2021Kei Nakai et al.II) and 1α, 25-dihydroxy Vitamin D3 (VitD3) were purchased from StemRD (ALK-010) and Cayman (Cat. no. 71820). The osteogenic medium (OM) consisted of the complete medium supplemented with 50 μg/ml ascorbic acid,

(17) Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageingScientific reportsMay 19, 2020Srikuea R, Hirunsai M, Charoenphandhu N.SMSCs were treated daily with vehicle (0.1% ethanol) or 1α,25(OH)2D3 (100 nM) (final concentrations) (71820) (Cayman Chemical, MI, USA) to assess the expression of vitamin D system-related proteins (VDR, CYP27B1,

(18) Responses of primary osteoblasts and osteoclasts from hemizygous β-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D₃Scientific reportsSeptember 27, 2019Charoenphandhu N, Aeimlapa R, Sooksawanwit S, Thongbunchoo J, Teerapornpuntakit J, Svasti S, Wongdee K.injected with vehicle (Veh; 3 mL/kg 9:1 propylene glycol-ethanol) or 0.5 μg/kg 1,25(OH)2D3 (catalog no. 71820; Cayman Chemical, Ann Arbor, MI, USA) for 7 days. After euthanasia, tibiae and femora were collected

(19) 1,25-Dihydroxyvitamin D3 Ameliorates Collagen-Induced Arthritis via Suppression of Th17 Cells Through miR-124 Mediated Inhibition of IL-6 SignalingFrontiers in ImmunologyFebruary 7, 2019Li Zhou, Julie Wang, Jingren Li, Ting Li, Yanming Chen, Rayford R. June, Song Guo Zhengdetermine intervention effects, mice were intraperitoneally treated with 0.5 μg/mice VD (Catalog NO.71820, Cayman Chemical) dissolved in 0.1% ethanol every other day starting 1 day before immunization for 15

(20) Vitamin D attenuates cerebral artery remodeling through VDR/AMPK/eNOS dimer phosphorylation pathway after subarachnoid hemorrhage in ratsJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismFebruary 1, 2019Enkhjargal B, Malaguit J, Ho WM, Jiang W, Wan W, Wang G, Tang J, Zhang JH.environment and fed ad libitum. Naı̈ve rats were pretreated a single 30 ng/kg of VitD3 (calcitriol, 71820, Cayman Chemical, MI, USA) (þVitD3) by intranasal route to study the eﬀect of VitD3 on endogenous expression

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Calcitriol

Calcitriol

Calcitriol from Cayman Chemical

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Cayman Chemical

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Calcitriol from Cayman Chemical

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