CAY10592 from Cayman Chemical

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CAY10592

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Description

A selective PPARd agonist that acts as a partial agonist (EC50 = 53 nM) in transactivation assays and as a full agonist (EC50 = 30 nM) in the oxidation of free fatty acid; increases HDL levels, decreases LDL and TG levels, and improves insulin sensitivity in high fat fed ApoB100/CETP-transgenic mice at a dose of 20 mg/kg