Trolox from Cayman Chemical

Product Specs
ItemTrolox
CompanyCayman Chemical
Price $43.00Supplier Page View Company Product Page
Catalog Number10011659
Quantity250 mg
Research AreaCancer, Cell Biology, Cell Death, Neuroscience
FormatA crystalline solid
Molecular Weight250.3
Purity≥98%
Storage-20
FormulaC14H18O4
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal MetastasisCancer ResApril 16, 2026Amal T. Elhaw, Priscilla W. Tang, Ya-Yun Cheng, Shriya Kamlapurkar, Zaineb Javed, Sarah Al-Saad, Sierra R. White, Ahmed Emam Abdelnaby, Hannah Khan, Alex Seok Choi, et al.containing 10 mM sodium ascorbate (Sigma-Aldrich), 10 mM sodium azide, and 5 mM Trolox (Cayman Chemical, 10011659; pH 8.0), followed by three washes in the same solution (30). Biotinylated proteins were captured using

(2) Differential assembly of RNP granules via activation of distinct dsRNA sensors by adenovirus mutantsbioRxivFebruary 21, 2026Robert T. Steinbock, Orlando B. Scudero, Joseph M. Dybas, Amber R. N. Abbott, Katarzyna Kulej, Richard Lauman, Holly Chan, Eva L. Agostino, Namrata Kumar, Skyler Briggs, et al.of 1 mM for 60 s before quenching the biotinylation reaction with Trolox (Cayman Chemical Company, 10011659) and sodium L-ascorbate (Sigma-Aldrich, A7631) at final concentrations of 5 and 10 mM, respectively.

(3) Longan flower water extract promotes sleep in mice via the serotonin–melatonin axisJournal of the Science of Food and AgricultureFebruary 1, 2026Tzu‐Huan Hung, Chiu‐Ping Cheng, Wei‐Chung Chiou, Tzu‐Lan Hsia, Hui‐Kang Liu, Hsu‐Feng Lu, Yu‐Heng Lai, Shang‐Ting Tsai, Chiung‐Ju Chen, Cheng Huanga microplate reader. A calibration curve was constructed using Trolox (Cayman, USA, catalog number 10011659) as the standard, at concentrations ranging from 0 to 60 μg mL−1. Antioxidant activity was expressed

(4) Development of an inhibitory TTC7B selective nanobody that blocks EFR3 recruitment of PI4KAJournal of Biological ChemistryNovember 4, 2025Sushant Suresh, Alexandria L. Shaw, Damilola K. Akintola, Martine Lunke, Sophia Doerr, Pooja Rohilla, Tamas Balla, Calvin K. Yip, Scott D. Hansen, Jennifer A. Cobb, et al.catalase (Sigma, catalog no.: C40–100MG, bovine liver), and 1 mM Trolox (Cayman Chemicals, catalog no.: 10011659). Trolox was prepared using a previously described protocol that utilized UV irradiation to drive the

(5) CYB5R4 sustains endothelial proliferation and ischemia-induced angiogenesis by maintaining RRM2-dependent nucleotide balancebioRxiv : the preprint server for biologySeptember 20, 2025Yuan S, Hahn SA, Colussi NC, Mullett SJ, Gelhaus SL, Schopfer FJ, Straub AC.biotinylation. Reactions were quenched (10 mM sodium ascorbate, 10 mM sodium azide, 5 mM Trolox [Cayman, 10011659] in phosphate-buffered saline, pH 8), cells were lysed, and biotinylated proteins were enriched with

(6) SH2-mediated steric occlusion of the C2 domain regulates autoinhibition of SHIP1 inositol 5-phosphatasebioRxivSeptember 11, 2025Emma E. Drew, Hunter G. Nyvall, Matthew A.H. Parson, Reed K. Talus, John E. Burke, Scott D. HansenAspergillus niger), 50 μg/mL catalase (Sigma, #C40-100MG Bovine Liver), and 2 mM Trolox (Cayman Chemicals, cat #10011659). Trolox was prepared using a previously described protocol that utilized UV irradiation to drive the

(7) Potent antioxidant and mitochondrial-protective effects of ATH434, a moderate affinity iron chaperoneThe Journal of biological chemistrySeptember 1, 2025Bailey DK, Nihlawi R, Bradbury MJ, Bond S, Kosman DJ.DFX (Cat. #HY-17359), 8-Quinolinol (Cat. #HY-B1005) were purchased from MedChemExpress. Trolox (Cat. #10011659) and a-tocopherol (Cat. #25985) were purchased from Cayman Chemical. N-ethylmaleimide (Cat. #E1271),

(8) Dynamic interaction of REEP5-MFN1/2 enables mitochondrial hitchhiking on tubular ERThe Journal of cell biologyOctober 7, 2024Chen S, Sun Y, Qin Y, Yang L, Hao Z, Xu Z, Björklund M, Liu W, Hong Z.the manufacturer and then replaced with a low-glucose medium for 3 h before imaging. 500 μM Trolox (10011659; Cayman Chemical) was added to reduce phototoxicity. Cells were maintained at 37°C and 5% CO2 during

(9) Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14Cell ReportsDecember 26, 2023Zoey A. Miller, Arielle Mueller, TaeBeom Kim, Jennifer F. Jolivert, Ray Z. Ma, Sahil Muthuswami, April Park, Derek B. McMahon, Kevin T. Nead, Ryan M. Carey, et al.,Cayman Chemical,11126 Isoproterenol,Cayman Chemical,15592 YM254890,Cayman Chemical,29735 Trolox,Cayman Chemical,10011659 N-acetyl-L-Cysteine,Cayman Chemical,20261 Pertussis Toxin,Tocris,3097 Denatonium Benzoate,TCI Chemicals,D2124 ATP,Millipore Sigma

(10) Mechanisms controlling membrane recruitment and activation of the autoinhibited SHIP1 inositol 5-phosphataseThe Journal of biological chemistryAugust 1, 2023Waddell GL, Drew EE, Rupp HP, Hansen SD.catalase (Sigma; catalog no.: C40-100MG, bovine liver), and 2 mM Trolox (Cayman Chemicals; catalog no.: 10011659). Trolox was prepared using a previously described protocol that utilized UV irradiation to drive the

(11) Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domaineLifeJuly 7, 2023Noah J Harris, Meredith L Jenkins, Sung-Eun Nam, Manoj K Rathinaswamy, Matthew A H Parson, Harish Ranga-Prasad, Udit Dalwadi, Brandon E Moeller, Eleanor Sheeky, Scott D Hansen, et al.compound, drug",Catalase,Sigma,C40-100MG Bovine Liver, "Chemical compound, drug",Trolox,Cayman Chemicals,10011659, "Chemical compound, drug",Dyomics 647 maleimide dye,Dyomics,647P1-03, "Chemical compound, drug",Coenzyme

(12) Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension cultureScientific ReportsJune 1, 2023Mitchell J. S. Braam, Jia Zhao, Shenghui Liang, Shogo Ida, Nick K. Kloostra, Diepiriye G. Iworima, Mei Tang, Robert K. Baker, Nina Quiskamp, James M. Piret, et al.II, 1 mM N-acetyl cysteine (Millipore Sigma, Cat#A9165), 10 μM Trolox (Cayman Chemical Company, Cat#10011659–250), 2 μM R428 (Cayman Chemical Company, Cat#21523–1), 10 μM zinc sulfate and 10 μg/mL heparin) for

(13) Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domainbioRxivMay 27, 2023Noah J Harris, Meredith L Jenkins, Sung-Eun Nam, Manoj K Rathinaswamy, Matthew AH Parson, Harish Ranga-Prasad, Udit Dalwadi, Brandon E Moeller, Eleanor Sheekey, Scott D Hansen, et al.niger (225 U/mg),Biophoretics,B01357.02 catalase,Sigma,C40-100MG Bovine Liver Trolox,Cayman Chemicals,10011659 Dyomics 647 maleimide dye,Dyomics,647P1-03 Coenzyme A,Sigma,C3019 Sulfuric acid,Sigma,58105-2.5L-PC Critical

(14) CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusionNatureApril 27, 2023Iain F. Davidson, Roman Barth, Maciej Zaczek, Jaco van der Torre, Wen Tang, Kota Nagasaka, Richard Janissen, Jacob Kerssemakers, Gordana Wutz, Cees Dekker, et al.G2133), 35 mg ml−1 catalase (Sigma-Aldrich, C-40), 9 mg ml−1 b-d-glucose, 2 mM trolox (Cayman Chemical, 10011659)) and 5 mM ATP (Jena Biosciences, NU- 1010-SOL)) supplemented with 20 nM Sytox Orange at 100 µl min−1.

(15) Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRsCell ReportsMarch 28, 2023Manoj K. Rathinaswamy, Meredith L. Jenkins, Benjamin R. Duewell, Xuxiao Zhang, Noah J. Harris, John T. Evans, Jordan T.B. Stariha, Udit Dalwadi, Kaelin D. Fleming, Harish Ranga-Prasad, et al.B01357.02), 50 μg/mL catalase (Sigma, #C40-100MG Bovine Liver), and 2 mM Trolox (Cayman Chemical, Cat#10011659).61 Perishable reagents (i.e. glucose oxidase, catalase, and Trolox) were added 5–10 min before image

(16) ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolismCancer & metabolismDecember 3, 2021Khare S, Kim LC, Lobel G, Doulias PT, Ischiropoulos H, Nissim I, Keith B, Simon MC.,Sigma Aldrich,G6264 Thymidine,Sigma Aldrich,T1895 Cytidine,Sigma Aldrich,C4654 Trolox,Cayman Chemical,10011659 N-acetyl-l-cysteine,Sigma Aldrich,A7250 Enhanced chemiluminescent substrate,Perkin Elmer,NEL105001EA Matrigel matrix

(17) Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherolCommunications BiologyDecember 1, 2021Daisuke Anegawa et al.Deferoxamine (Sigma Aldrich, D9533), Ferrostatin-1 (Sigma Aldrich, SML0583), Trolox (Cayman Chemical, 10011659), vitamin C (Ascorbic acid) (Wako, 012-04802), RSL3 (Sigma Aldrich, SML2234), BSO (Cayman Chemical,

(18) Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammationRedox BiologyNovember 1, 2021Shuai Yuan et al.repeated washing with the quench buffer (10 mM sodium ascorbate, 10 mM sodium azide, 5 mM Trolox [Cayman, 10011659] in phosphate-buffered saline, pH 8). Biotinylated proteins were enriched using Dynabeads™ M − 280 Streptavidin

(19) Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanismCellOctober 14, 2021Benedikt W. Bauer, Iain F. Davidson, Daniel Canena, Gordana Wutz, Wen Tang, Gabriele Litos, Sabrina Horn, Peter Hinterdorfer, Jan-Michael Peters(Sigma; G2133), 35 μg/ml catalase (Sigma; C- 40), 9 mg/ml β-D-glucose, 2 mM Trolox (Cayman Chemical; 10011659)), 1 mM DTT, 220 nM Sytox Orange and 5 mM ATP (Jena Biosciences; NU-1010-SOL) at 100 μl/min. Stock solutions

(20) FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cellsiScienceSeptember 24, 2021Kamasaki T, Miyazaki Y, Ishikawa S, Hoshiba K, Kuromiya K, Tanimura N, Mori Y, Tsutsumi M, Nemoto T, Uehara R, et al.peptides, and recombinant proteins" ,, ML141,Tocris Bioscience,Cat#4266 Trolox,Cayman Chemical,Cat#10011659 Blasticidin,Invivogen,Cat#ant-bl-1 Zeocin,Invivogen,Cat#ant-zn-1 G418 (Geneticin),GIBCO,Cat#10131027 Tetracycline,Sigma-Aldrich,Cat#T7660 Paraformaldehyde,Sigma-Aldrich,Cat#6148 Glutaraldehyde,Electron

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Trolox

Trolox

Trolox from Cayman Chemical

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Cayman Chemical

Citations (25)

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Trolox from Cayman Chemical

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