L-NIL (hydrochloride) from Cayman Chemical

Product Specs
ItemL-NIL (hydrochloride)
CompanyCayman Chemical
Price $394.00Supplier Page View Company Product Page
Catalog Number80310
Quantity100 mg
FormatA crystalline solid
Molecular Weight260.2
Purity≥95%
TypeInhibitors
Research AreaImmunology & Inflammation, Infectious Disease, Parasitic Diseases
Storage-20
FormulaC8H17N3O2 • 2HCl
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Mitochondrial transfer to granulocytic myeloid-derived suppressor cells augments immunosuppressive activityCell ReportsMarch 24, 2026Prabhakar Arumugam, Cortney E. Heim, Rachel W. Fallet, Dhananjay D. Shinde, Vinai C. Thomas, Rafael J. Argüello, Tammy KielianHyClone,SH30237.01 G-CSF,BioLegend,574608 GM-CSF,BioLegend,576308 IL-6,BioLegend,575708 N-Acetyl-L-cysteine,Thermo Fisher Scientific,160280250 L-NIL,Cayman Chemical,80310 nor-NOHA,Cayman Chemical,10006861 CAY10452,Cayman Chemical,10075 Critical commercial assays,Critical

(2) Complement Anaphylatoxin C5a-Induced Mouse Lymphatic Functions Modulate Interactions Between Endothelial Cells and T LymphocytesImmune NetworkFebruary 10, 2026Haydn E. Rich, Yi-Dong Li, Kathryn D. Hok, Stacey L. Mueller-Ortiz, Aleksey Y. Domozhirov, Anthony Shadid, Rajarajan A. Thandavarayan, Hari Krishna Yalamanchili, Marie-Francoise Doursout, Tingting Weng-Mills, et al.iNOS inhibition, a selective iNOS inhibitor, N6-(1-Iminoethyl)-L-lysine hydrochloride (L-NIL, Cat# 80310; Cayman Chemicals, Ann Arbor, MI, USA), was given 1 h before the administration of C5a, at 60 µg/40

(3) Quantitative Proteomics of Nitrosylated Proteins in Melanoma Using the Biotin-Switch Technique Combined With Tandem Mass Tag LabelingBio ProtocDecember 5, 2025Vipin K. Yadav, Bin Fang, John M. Koomen, Jyoti Srivastava, Sanjay PremiS8337) 18. L-NIO (Cayman Chemical, catalog number: 80320) 19. L-NIL (Cayman Chemical, catalog number: 80310) 20. CPTIO (Cayman Chemical, catalog number: 81540) 21. Ultrapure water (Millipore, catalog number:

(4) Quantitative Proteomics of Nitrosylated Proteins in Melanoma Using the Biotin-Switch Technique Combined With Tandem Mass Tag LabelingBio ProtocDecember 5, 2025Vipin K. Yadav, Bin Fang, John M. Koomen, Jyoti Srivastava, Sanjay PremiS8337) 18. L-NIO (Cayman Chemical, catalog number: 80320) 19. L-NIL (Cayman Chemical, catalog number: 80310) 20. CPTIO (Cayman Chemical, catalog number: 81540) 21. Ultrapure water (Millipore, catalog number:

(5) Blocking Nitrosylation Induces Immunogenic Cell Death by Sensitizing NRAS-Mutant Melanoma to MEK InhibitorsCancer ResApril 27, 2025Jyoti Srivastava, Vipin K. Yadav, Rachel V. Jimenez, Pravin R. Phadatare, Ninad A. Inamdar, Montana M. Young, Antonella Bacchiocchi, Ruth Halaban, Bin Fang, Alvaro de Mingo Pulido, et al.L-NAME (0665, Tocris), 1 mmol/L L-NIL, 1 mmol/L L-NIO, 100 µmol/L aminoguanidine, and 1 mmol/L L-NNA (80310, 80320, 81530, 10005031, and 80220, Cayman Chemical). Nitric oxide scavengers included 100 µmol/L carboxy-PTIO

(6) Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathwayPloS oneJanuary 1, 2025Ferrini MG, Abraham A, Millán R, Graciano L, Eleswarapu SV, Rajfer J.pathway were employed in the experiments. L-NIL, a specific inhibitor of iNOS (L-NIL hydrochloride, Cat# 80310, Cayman Chemical, Ann Arbor, MI), was used at 2 μM; L-NAME, a non-selective inhibitor of all three NOS

(7) Glucose transporter 1 is essential for the resolution of methicillin-resistant S. aureus skin and soft tissue infectionsCell reportsJuly 23, 2024Banerjee SK, Thurlow LR, Kannan K, Richardson AR.,Thermo Fisher Scientific,Cat# C10444 STF31,Cayman chemicals,Cat# 11173 L-NIL Hydrochloride,Cayman chemicals,Cat# 80310 Apocynin,Cayman chemicals,Cat# 11976 Rosiglitazone,Cayman chemicals,Cat# 71740 GW9662,Cayman chemicals,Cat#

(8) Mitochondrial Fragmentation in a High Homocysteine Environment in Diabetic RetinopathyAntioxidants (Basel, Switzerland)February 11, 2022Kowluru RA, Mohammad G.a selective inhibitor of iNOS, 30 µM of N6-(1-iminoethyl)-L-lysine, dihydrochloride (NIL, Cat. No. 80310; Cayman Chemical, Ann Arbor, MI, USA; HG/NIL and HG + Hcy/NIL groups, respectively) [27]. A batch of

(9) A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO(•) sabotage of theft-ferroptosisRedox biologySeptember 1, 2021Dar HH, Anthonymuthu TS, Ponomareva LA, Souryavong AB, Shurin GV, Kapralov AO, Tyurin VA, Lee JS, Mallampalli RK, Wenzel SE, et al.(Selleck Chemicals, S2619), P3421 (Selleck Chemicals, S1013), 1400W (Cayman, 81520), L-NIL (Cayman, 80310), BSA (Sigma-Aldrich), DETA-NONOate and DPTA-NONOate (Caymen Chemical), NADPH (Sigma), Glutathione peroxidase

(10) Activation of the iNOS/NO/cGMP pathway by Revactin® in human corporal smooth muscle cellsTranslational Andrology and UrologyJuly 1, 2021Monica G. Ferrini, Andrea Abraham, Leslie Graciano, Sabine Nguyen, Jesse N. Mills, Jacob Rajfer139755-83-2), and the iNOS specific inhibitor, N6-(1-iminoethyl)-Llysine, dihydrochloride (L-NIL; cat#: 80310) were obtained from Cayman Chemical Company (Ann Arbor, MI) and used at a concentration of 1 mM for

(11) Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic InflammationCell reportsOctober 23, 2018Lee CH, Kim HJ, Lee YS, Kang GM, Lim HS, Lee SH, Song DK, Kwon O, Hwang I, Son M, et al.(L-NAME),Sigma,Cat# N5751; CAS: 51298–62-5 L-N6-(1-Iminoethyl)lysine dihydrochloride (L-NIL),Cayman Chemical,Cat# 80310; CAS: 159190–45-1 Sodium nitroprusside,Sigma,Cat# 1614501; CAS:13755–38-9 ,, Critical Commercial

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