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Protein Biochemistry
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SQ 29,548
SQ 29,548 from Cayman Chemical
Be the first to write a review!
Citations:
(12)
Supplier Page
Supplier Page from
Cayman Chemical for
SQ 29,548
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Description
Selective TXA2 receptor antagonist (Ki = 4.1 nM); inhibits U-46619-induced platelet aggregation (IC50 = 0.06 µM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
SQ 29,548
Company
Cayman Chemical
Price
$94.00
Supplier Page
View Company Product Page
Catalog Number
19025
Quantity
1 mg
Format
A crystalline solid
Molecular Weight
387.5
Purity
≥98%
Research Area
Blood, Cardiovascular System, Coagulation & Hemostasis, Cyclooxygenase Pathway, Lipid Biochemistry, Smooth Muscle Cells, Vasculature, Vasodilation
Storage
-20
Formula
C21H29N3O4
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (12)
(1)
TBXA2R activates ERMs to drive motility, invasion, and metastatic colonization of TNBC cells
Life Sci Alliance
March 17, 2026
Kévin Leguay, Omaima Naffati, Camila Lie Kiyan, Yu Yan He, Mireille Hogue, Chloé Tesnière, Melania Gombos, Hellen Kuasne, Louis Gaboury, Christian Le Gouill,
et al.
from NanoLight Technology (#340). U46619 and SQ-29548 were purchased from
Cayman Chemical
(#
16450
and #
19025
, respectively).
Calyculin A
and
Y-27632
ROCK
inhibitors
were purchased from
Sigma-Aldrich
(#
C5552
and
(2)
Alox15 via H2O2 mediates TP receptor palmitoylation and its membrane trafficking leading to platelet activation
iScience
February 20, 2026
Suresh Govatati, Chandra Sekhar Yadavalli, Abhinav Sunkara, Gadiparthi N. Rao
Company,Item No.
34570
ML351,
Cayman Chemical Company
,Item No.
16119
SQ29548,
Cayman Chemical Company
,Item No.
19025
Acid citrate dextrose,
G-Biosciences
,
786–493
Go6976
,,
HY-10183
VTX27,
MedChemExpress
,
HY-112782
/CS-0064140 2-Bromopalmitate,
MedChemExpress
,
HY-111770
Enhanced
(3)
Expression and function of β-site amyloid precursor protein-cleaving enzyme 2 in vascular endothelium
American Journal of Physiology-Heart and Circulatory Physiology
August 1, 2025
Livius V. d’Uscio, Tetiana Kovalenko, Tongrong He, Trace A. Christensen, Jeffrey L. Salisbury, Zvonimir S. Katusic
ester (L-NAME; 3×10−4 mol/L, 30 minutes; Cat# N5751; Sigma) or SQ29548 (1 μmol/L, 30 minutes; Cat#
19025
;
Cayman Chemical
, Ann Arbor, MI). In addition,
endothelium
-dependent relaxations in response to acetylcholine
(4)
Platelet activation in patients with peripheral artery disease from 43 sites: Assessment of samples transported by overnight mail
JVS-Vascular Insights
March 22, 2025
William B. Stubblefield, Alexander E. Sullivan, Katherine N. Cahill, Taneem Amin, Olivier Boutaud, Irene Zagol-Ikapitte, Yan Ru Su, David K. Flaherty, Brittany K. Matlock, Jeffrey Berger,
et al.
#A6635), carbaprostacyclin (
Cayman Chemical
#
18210
; Ann Arbor, MI), and
SQ 29,548
(
Cayman Chemical
#
19025
).11 PBS was obtained from Gibco (
Thermo Fisher Scientific
#
10010
–023; Waltham, MA). The dilysyl-malondialdehyde
(5)
Early-age efferocytosis directs macrophage arachidonic acid metabolism for tissue regeneration
Immunity
February 11, 2025
Connor Lantz, Amanda Becker, Matthew DeBerge, Mallory Filipp, Kristofor Glinton, Aparnaa Ananthakrishnan, Jessica Urbanczyk, Madeline Cetlin, Afnan Alzamroon, Ahmed Abdel-Latif,
et al.
and recombinant proteins"
U-46619
,
Cayman Chemicals
,Cat #:
16450
"SQ29,548",
Cayman Chemicals
,Cat #:
19025
S18886
,
Cayman Chemicals
,Cat #:
14059
Picotamide
,
Cayman Chemicals
,Cat #:
21690
Ozagrel
,
Cayman Chemicals
,Cat
(6)
Glucagon-like Peptide-1 Receptor Pathway Attenuates Platelet Activation in Aspirin-Exacerbated Respiratory Disease
The Journal of Immunology
December 15, 2023
Dinah Foer, Taneem Amin, Jun Nagai, Yumi Tani, Chunli Feng, Tao Liu, Dawn C. Newcomb, Juying Lai, Hiroaki Hayashi, William E. Snyder,
et al.
apyrase (Sigma# A6635), carbaprostacyclin (
Cayman Chemical
#
18210
) and
SQ 29,548
(
Cayman Chemical
#
19025
)(27, 28). Thromboxane (TXA2) analogue U46619 was from
Cayman Chemical
(#
16450
). Use of the reagent is
(7)
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model
The Journal of experimental medicine
May 2, 2022
Tao X, Zhang R, Du R, Yu T, Yang H, Li J, Wang Y, Liu Q, Zuo S, Wang X,
et al
.
(#
10010744
),
PF-04418948
(#
15016
),
L-798,106
(#
11129
), sulprostone (#
14765
), L161982 (#
10011565
), SQ29548 (#
19025
),
CAY10441
(#
10005186
), AL8810 (#
16735
), and
BW A868C
(#
12060
) from
Cayman Chemical
. CCL4 (#1601168),
(8)
Loss of Transforming Growth Factor Beta Signaling in Aortic Smooth Muscle Cells Causes Endothelial Dysfunction and Aortic Hypercontractility
Arteriosclerosis, thrombosis, and vascular biology
June 1, 2021
Zhu J, Angelov S, Alp Yildirim I, Wei H, Hu JH, Majesky MW, Brozovich FV, Kim F, Dichek DA.
(10−5 M;
Cayman Chemical
#
11731
), the thromboxane A2 receptor antagonist SQ-
25948
(10−5 M;
Cayman
#
19025
), the nitric oxide synthase
inhibitor
N(ω)-nitro-L-arginine methyl ester (L-NAME; 10−4 M;
Cayman
#
80210
)
(9)
Thromboxane A2 receptor antagonist SQ29548 attenuates SH‑SY5Y neuroblastoma cell impairments induced by oxidative stress
International Journal of Molecular Medicine
March 27, 2018
Gaoyu Cai, Aijuan Yan, Ningzhen Fu, Yi Fu
(cat. no. T8787) were purchased from
Sigma‑Aldrich
(Merck KGaA, Darmstadt, Germany). SQ29548 (cat. no.
19025
) was obtained from
Cayman Chemical Company
(Ann Arbor, MI, USA). Bovine serum albumin (BSA; cat. no.
(10)
High-Level Expression, Purification and Characterization of a Constitutively Active Thromboxane A2 Receptor Polymorphic Variant
PLoS ONE
September 23, 2013
Bing Xu, Raja Chakraborty, Markus Eilers, Shyamala Dakshinamurti, Joe D. O’Neil, Steven O. Smith, Rajinder P. Bhullar, Prashen Chelikani
purchased from PerkinElmer (NET 936), and cold
SQ 29,548
was obtained from
Cayman Chemicals
(Cat #
19025
). Buffers used were as follows: PBS buffer, 137 mM NaCl, 2.7 mM KCl, 1.8 mM KH2PO4, 10 mM Na2HPO4 (pH7.4);
(11)
Functional Enhancement of AT1R Potency in the Presence of the TPαR Is Revealed by a Comprehensive 7TM Receptor Co-Expression Screen
PLoS ONE
March 14, 2013
Jonas Tind Hansen, Christina Lyngsø, Tobias Speerschneider, Pernille B. L. Hansen, Céline Galés, David M. Weiner, Søren P. Sheikh, Ethan S. Burstein, Jakob Lerche Hansen
9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α (U46619) (
D8174
) were purchased from
Sigma Aldrich
, SQ29548 (
19025
) was purchased from
Cayman Chemical
, myo-[2-3H]inositol was purchased from Amersham Biosciences, Coelenterazine
(12)
Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism
Cell death and differentiation
August 1, 2012
Iorio-Morin C, Germain P, Roy S, Génier S, Labrecque P, Parent JL.
P4394
) and cycloheximide (cat.
C4859
) were from
Sigma-Aldrich
. U46619 (cat.
16450
) and SQ29548 (cat.
19025
) were from
Cayman Chemical Company
. Plasmid constructs. The full-length open reading frame of
Siva1
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Reviews
Be the First to Write a Review!
SQ 29,548 from Cayman Chemical
Supplier Page
View Company Product Page
$94.00
Product Specs
Company Info
Citations
Reviews
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