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SIN-1 (chloride)
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SIN-1 (chloride)
SIN-1 (chloride)
SIN-1 (chloride) from Cayman Chemical
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Citations:
(7)
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SIN-1 (chloride)
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Description
Active metabolite of molsidomine that acts as a potent vasorelaxant and inhibitor of platelet aggregation; produces both NO and superoxide to generate peroxynitrite under physiological conditions
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
SIN-1 (chloride)
Company
Cayman Chemical
Price
$247.00
Supplier Page
View Company Product Page
Catalog Number
82220
Quantity
100 mg
Research Area
Blood, Cardiovascular System, Coagulation & Hemostasis, Oxidative Stress & Reactive Species, Pro-oxidant Activity, Reactive Nitrogen, Reactive Oxygen, Vasculature, Vasodilation
Format
A crystalline solid
Molecular Weight
206.6
Purity
≥99%
Storage
-20
Formula
C6H11N4O2 • Cl
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (7)
(1)
Combined Pharmacological Conditioning of Endothelial Cells for Improved Vascular Graft Endothelialization
Int J Mol Sci
July 25, 2025
Zhiyao Lu, Xuqian Zhou, Xiaowen Liu, Chunyan Liu, Junfeng Zhang, Lei Dong
Antibody,Source,Identifier SNP,"KeyGen BioTECH (Nanjing, China)",Cat#KGR0017 SIN-1,"Cayman Chemical (Ann Arbor, MI, USA)",Cat#
82220
SNAP
,"
Cayman Chemical
(Ann Arbor, MI, USA)",Cat#82250
Hydrocortisone
,"
MCE
(Monmouth Junction, NJ,
(2)
An early glycolysis burst in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuroinflammation
iScience
October 20, 2023
Hamid Suhail, Mohammad Nematullah, Faraz Rashid, Mir Sajad, Mena Fatma, Jaspreet Singh, Insha Zahoor, Wing Lee Cheung, Nivedita Tiwari, Kameshwar Ayasolla,
et al.
#
17149
L-NAME (hydrochloride
),
Cayman Chemical
,Cat #
80210
SIN-1 (chloride
),
Cayman Chemical
,Cat #
82220
(R)-3-hydroxy Tetradecanoic Acid,
Cayman Chemical
,Cat #
16871
BX 795
(
PDPK1
inhibitor
),
Tocris
,Cat #
(3)
Alterations of lipid-mediated mitophagy result in aging-dependent sensorimotor defects
Aging cell
October 1, 2023
Oleinik N, Albayram O, Kassir MF, Atilgan FC, Walton C, Karakaya E, Kurtz J, Alekseyenko A, Alsudani H, Sheridan M,
et al
.
Inhibitor,Sigma,P8340 Trypsin/EDTA,
Sigma
,
T4049
Doxycycline Chloride,Sigma,D3072
SIN‐1 Chloride
,
Cayman Chemical Company
,
82220
Sodium Selenite
,
Sigma
,
S5261
Mtphagy Dye,"Dojindo Molecular Technologies, Inc., MT02",MT02
P62‐mediated mitophagy inducer
(4)
Role of constitutive nitric oxide synthases in the dynamic regulation of the autophagy response of keratinocytes upon UVB exposure
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
November 11, 2020
Bahamondes Lorca VA, Wu S.
final concentrations of 0.0125, 0.05 and 0.1 mM. 3-Morpholino-sydnonimine (SIN-1,
Cayman Chemical
,
82220
) was prepared in DMSO and diluted prior to use in cell medium to final concentrations of 0.0015, 0.005,
(5)
Sensing Peroxynitrite in Different Organelles of Murine RAW264.7 Macrophages With Coumarin-Based Fluorescent Probes
Frontiers in Chemistry
February 20, 2020
Maria Weber, Namiko Yamada, Xue Tian, Steven D. Bull, Masafumi Minoshima, Kazuya Kikuchi, Amanda B. Mackenzie, Tony D. James
Balanced Salt Solution (HBSS) (2 × 2 ml) followed by the addition of 100 μM SIN-1 (
Cayman Chemical
,
82220
) in phenol red-free DMEM and incubated for 30 min or 1 h at 37°C in 5% CO2, as indicated. The SIN-1
(6)
The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis
Stem cell research
September 1, 2015
Sangani R, Periyasamy-Thandavan S, Pathania R, Ahmad S, Kutiyanawalla A, Kolhe R, Bhattacharyya MH, Chutkan N, Hunter M, Hill WD,
et al
.
(shSVCT2), we pre-incubated the cells with oxidant (Sin-1 200 μM, 400 μM and 600 μM) (
Cayman chemical
,
82220
), antioxidant (Ascorbic acid (AA), Acros organics, 352681000) (250μM) and a combination of oxidant and
(7)
Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme
Archives of Biochemistry and Biophysics
April 1, 2015
Chintan N. Koyani, Joerg Flemmig, Ernst Malle, Juergen Arnhold
used within 2 h after dilution. 5-Amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride (SIN-1,
Cayman
-
82220
), aminophenyl fluorescein (
APF
,
Cayman
-
10157
), potassium cyanide (KCN, Sigma–Aldrich-60178), 4-aminobenzoic
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SIN-1 (chloride) from Cayman Chemical
Supplier Page
View Company Product Page
$247.00
Product Specs
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