Description
A potent tyrosine kinase inhibitor; inhibits EGF receptor-associated tyrosine kinase, pp60c-src(+) kinase, and Ca2+ calmodulin-dependent kinase II (IC50s = 0.012, 0.5, and 0.2 µM, respectively); inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation at 10-150 µM