Description
An anticoagulant and vitamin K antagonist; inhibits VKOR (IC50 = 1.5 and 5.8 nM for VKORC1 and VKORC1L1, respectively); inhibits a variety of VKOR mutants in cell-based reporter assays (IC50s = 0.54-11.21 nM); prolongs prothrombin time in rat blood at 1.5 mg/kg