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CAY10526
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CAY10526
CAY10526
CAY10526 from Cayman Chemical
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Citations:
(5)
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Cayman Chemical for
CAY10526
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Description
An inhibitor of PGE2 production through the selective modulation of mPGES-1 expression; dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells (IC50 = 1.8 µM) without affecting COX-2 expression
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
CAY10526
Company
Cayman Chemical
Price
$274.00
Supplier Page
View Company Product Page
Catalog Number
10010088
Research Area
Cyclooxygenase Pathway, Immunology & Inflammation, Inflammatory Lipid Mediators, Innate Immunity, Lipid Biochemistry, Prostaglandins
Format
A crystalline solid
Molecular Weight
311.1
Purity
≥98%
Storage
-20
Formula
C12H7BrO3S
Origin
USA
Type
Inhibitors
Quantity
5 mg
Specifications/Features
Ki, IC, EC, or working concentration
: IC50 = 1.8 µM
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (5)
(1)
A moderate dosage of Prostaglandin E2-mediated Annexin A1 upregulation promotes alkali-burned corneal repair
iScience
December 15, 2023
Hongling Liu, Xue Zhang, Qiang Tan, Lingling Ge, Jia Lu, Chunge Ren, Baishijiao Bian, Yijian Li, Yong Liu
proteins" ,, PGE2,
Cayman Chemical
,Cat#
14010
dmPGE2,
Cayman Chemical
,Cat#
14750
CAY10526
,
Cayman Chemical
,Cat#
10010088
Ac2-26
,
Tocris Bioscience
,Cat#
1845
NaOH,Sangon biotech,Cat#A620617 Phosphate buffer saline (PBS),HyClone,Cat#SH30256.LS DMSO,
Sigma-Aldrich
,Cat#
D8418
TRIzol reagent
(2)
Growth of T-cell lymphoma cells is inhibited by mPGES-1/PGE2 suppression via JAK/STAT, TGF-β/Smad3 and PI3K/AKT signal pathways
Translational Cancer Research
July 1, 2022
Yiqing Li, Meng Qiu, Boqi Li, Jie Xiao, Wenjuan Yang, Shuangfeng Xie, Yumo Du, Kezhi Huang, Danian Nie
blood of healthy volunteers. The anti-mPGES-1 antibody (#
10004350
) and
mPGES-1
inhibitor
CAY10526
(#
10010088
) were ordered from
Cayman Chemical Company
(Ann Arbor, MI, USA). Antibodies to
JAK2
(#
3230
),
STAT3
(#
9139
),
(3)
NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8
+
T cell responses
iScience
June 25, 2021
Souza COS, Ketelut-Carneiro N, Milanezi CM, Faccioli LH, Gardinassi LG, Silva JS.
hydrochloride,Sigma-Aldrich,Cat#19371-19-5 PGE2,
Cayman Chemical
,Cat#
14010
CAY10526
,
Cayman Chemical
,Cat#
10010088
Indomethacin
,
Sigma-Aldrich
,Cat#I8280
Nigericin sodium salt
,
Sigma-Aldrich
,Cat#
N7143
LPS-EK Ultrapure,InvivoGen,Cat#tlrl-peklps PMA,
Abcam
,Cat#
ab120297
Ionomicina,
Sigma-Aldrich
,Cat#
I0634
Brefeldin
(4)
mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway
Cell death & disease
April 6, 2020
Li Y, Chen J, Yang W, Liu H, Wang J, Xiao J, Xie S, Ma L, Nie D.
compliance with institutional guidelines). The anti-mPGES-1 antibody (10004350), mPGES-1
inhibitor
CAY10526
(
10010088
), exogenous PGE2 (
14010
), EP1 receptor
inhibitor
SC-19220
(
14060
),
EP2
receptor
inhibitor
AH-6809
(
14050
)
(5)
The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation
PLoS pathogens
August 1, 2016
Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM,
et al
.
Sigma-Aldrich
. AA861 (1μg/ml) and PD146176 (1μg/ml) were purchased from
BioMol International
.
CAY10526
(
10010088
),
KH7
(
13243
), Forskolin (
11018
),
Cytochalasin D
(
11330
), PGE2 (
14010
), PGD2 (
12010
) and U46619 (thromboxane
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CAY10526 from Cayman Chemical
Supplier Page
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$274.00
Product Specs
Company Info
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Reviews
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