Description
An inhibitor of MAO-B (Ki = 0.084 µM); selective for MAO-B over MAO-A (IC50s = 0.02 and 640 µM, respectively); inhibits rat liver MAO-B ex vivo (ED50 = 53 nmol/kg); inhibits ischemia-reperfusion injury-induced hydroxyl radical formation in mouse cerebral ventricles at 3 mg/kg