Forskolin from Cayman Chemical

Product Specs
ItemForskolin
CompanyCayman Chemical
Price $65.00Supplier Page View Company Product Page
Catalog Number11018
Quantity5 mg
FormatA crystalline solid
Purity≥98%
Molecular Weight410.5
Research AreacAMP Signaling, Cell Biology, Cell Signaling
Storage-20
FormulaC22H34O7
OriginCHN

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Dissection of Gαs and Hedgehog Signaling Cross-talk Reveals Therapeutic Opportunities to Target Hedgehog-Dependent TumorsCancer ResearchFebruary 16, 2026Sarah Krantz, Braden A. Bell, Katherine Lund, Natalia Salinas Parra, Yeap Ng, Natalia De Oliveira Rosa, Saikat Mukhopadhyay, Brad St. Croix, Kavita Y. Sarin, Roberto Weigert, et al.were treated with 50 μmol/L BAY60-6583, 50 μmol/L isoproterenol, 10 μmol/L forskolin (Cayman Chemical, 11018), 100 μmol/L IBMX (Sigma, I5879), 4 μmol/L VT-104 (Sigma, SML3445), and 20 μmol/L GANT61 (Tocris 3191).

(2) Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammationCell ReportsJanuary 27, 2026Jun Nagai, Madeline M. Hastings, Airi Nishida, Sreyashi Majumdar, Kendall Zaleski, Sofia A. Marshall, Junrui Lin, Mira A.S. Saliman, Yumi Tani, Yamato Murakami, et al.,Cayman Chemical,20210 Leukotriene D4,Cayman Chemical,20310 Leukotriene E4,Cayman Chemical,20410 Forskolin,Cayman Chemical,11018 H-89 (hydrochloride),Cayman Chemical,10010556 PF-04418948,Cayman Chemical,15016 EP4 Receptor Antagonist 1

(3) Galectin-3 in endometrial small extracellular vesicles promotes cytotrophoblast cell fusion during the implantation phaseCell Communication and SignalingDecember 20, 2025Tsutomu Ohara, Akihito Horie, Mitsuhiro Nakamura, Sachi Imakita, Asami Ikeda, Shimpei Shitanaka, Akihiro Yanai, Baku Nakakita, Yoshimi Kitawaki, Yusuke Sagae, et al.serum replacement (KnockOut Serum Replacement; #10828010, Thermo Fisher Scientific), 2 µM forskolin (#11018, Cayman Chemical), and 2.5 mM Y-27,632, as previously described [26]. Immunocytochemistry Immunostaining

(4) Pathogenic variants in KCTD1 disrupt cAMP signaling and cellular communication associated with developmental pathwaysJournal of Biological ChemistryDecember 1, 2025Yini Liao, Brian S. Muntean(2), MgCl2 (2), NaH2PO4 (1.25), NaHCO3 (10), glucose (10), and Hepes (5). Forskolin (Cayman Chemical #11018) was bath applied at 1 μM. As previously described (21, 23), images were acquired at 10 s intervals

(5) Modeling antithymocyte globulin-induced microvasculopathy using human iPSC-derived vascularized liver organoidsCell Reports MedicineNovember 6, 2025Shuntaro Kawamura, Yosuke Yoneyama, Norikazu Saiki, Yunheng Wu, Chiharu Moriya, Rio Ohmura, Mari Maezawa, Yoshihiro Shimada, Yicheng Wang, Kensaku Mori, et al.4, the medium was changed to StemPro-34 serum-free medium supplemented with 2 μM Forskolin (Cayman, 11018) and 200 ng/mL VEGF-A to induce differentiation into endothelial-like cells at 37°C with 5% CO2 for

(6) The pH-dependent photophysical and spectral properties of pH-sensing green fluorescent proteinsPhysiol RepOctober 18, 2025Ian M. Thornellratiometric pH measurements. One hour before measuring pH, fresh culture media containing 10 μM forskolin (11018 Cayman) was added to the basolateral surface of epithelia to stimulate CFTR‐dependent HCO− 3 secretion,

(7) Phosphorylation of presynaptic PLPPR3 controls synaptic vesicle releaseiScienceSeptember 19, 2025Cristina Kroon, Shannon Bareesel, Gerard Aguilar Perez, Domonkos Nagy-Herczeg, Dimitra Ranti, Vasiliki Syropoulou, Sandra Coveney, Marieluise Kirchner, Niclas Gimber, Willem Bintig, et al.one control treatment was carried out per experiment to ensure the solvent has no effect. Forskolin (#11018, Cayman Chemical) was used at a final concentration of 30 μM for 5-15 minutes, depending on the experiment

(8) Intracrine FFA4 signaling controls lipolysis at lipid dropletsNature Chemical BiologyAugust 5, 2025Shannon L. O’Brien, Emma Tripp, Natasja Barki, Elodie Blondel-Tepaz, Gabrielle Smith, Adam Boufersaoui, Jennie Roberts, Jeremy A. Pike, Joao Correia, Tamara Miljus, et al.(1747), 8-pCPT-2-O-Me-cAMP-AM (4853), ICI-118551 (0821) and CGP-12217 (1134) were from Tocris. Forskolin (11018), rosiglitazone (71740) and GC–MS fatty acid standards (17942) were from Cayman Chemical. Water (232178)

(9) Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespanEMBO Molecular MedicineJune 30, 2025Lucas Schoenfeldt, Patrick T Paine, Sara Picó, Nibrasul H Kamaludeen M, Grace B Phelps, Calida Mrabti, Gabriela Desdín-Micó, María del Carmen Maza, Kevin Perez, Alejandro Ocampo(D11347), Paraquat (856177); Cayman: Valproic Acid (13033), CHIR99021 (13122), Repsox (14794), Forskolin (11018), Doxorubicin (15007); Acros Organics: TCP (130472500); APExBIO: DZNep (A8182), Metformin (B1970); Seleckchem:

(10) Autophagosomes anchor an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signalingThe EMBO JournalApril 22, 2025Ashley Segura-Roman, Y Rose Citron, Myungsun Shin, Nicole Sindoni, Alex Maya-Romero, Simon Rapp, Claire Goul, Joseph D Mancias, Roberto ZoncuBiolegend (801202). Bafilomycin A1 (Alfa Aesar, J61835), Torin1 (Tocris, 4247), Forskolin (Cayman Chemical: 11018), Lenti-X concentrator (Takara Bio #631232). GFP-trap (gta) and mNeonGreen-trap (nta) from Proteintech/Chromotek.

(11) Multiple cAMP/PKA complexes at the STIM1 ER/PM junction specified by E-Syt1 and E-Syt2 reciprocally gates ANO1 (TMEM16A) via Ca2+Nat CommunApril 9, 2025Wei-Yin Lin, Woo Young Chung, Seonghee Park, Ava Movahed Abtahi, Benjamin Leblanc, Malini Ahuja, Shmuel MuallempF. Then, the currents were measured from the same cells exposed to 1 μM forskolin (Cayman Chemical, 11018) and 10 μM 3-isobutyl-1-methylxanthine (IBMX, Cayman Chemical, 13347) in a perfused bath solution. H89

(12) Phosphatases control the duration and range of cAMP/PKA microdomainsFunction (Oxf)March 24, 2025Filippo Conca, Doruk Kaan Bayburtlu, Mauro Vismara, Nicoletta C Surdo, Alessandra Tavoni, Leonardo Nogara, Adamo Sarra, Stefano Ciciliot, Giulietta Di Di Benedetto, Liliana F Iannucci, et al.duration and range of PKA microdomains. Materials and Methods Reagents Forskolin (FSK, Cat. No. 11018), 3-isobutyl-1-methylxantine (IBMX, Cat. No. 13347), and H-89 dihydrochloride (H-89, Cat. No. 10010556)

(13) Oxygen chemoreceptor inhibition by dopamine D2 receptors in isolated zebrafish gillsThe Journal of PhysiologyMarch 8, 2025Maddison Reed, Michael G. JonzD2R, the AC inhibitor SQ22536 (catalog. no. 1435; Tocris) and AC activator forskolin (catalog. no. 11018; Cayman Chemical, Ann Arbor, MI) were tested. All drugs were first dissolved in dimethyl sulphoxide

(14) Acute tuft cell ablation in mice induces malabsorption and alterations in secretory and immune cell lineages in the small intestinePhysiol RepMarch 6, 2025Michael Momoh, Francisca Adeniran, Cynthia Ramos, Kathleen E. DelGiorno, Hiroshi Seno, Joseph T. Roland, Izumi KajiIndomethacin (Cat# I7378) was dissolved in 100% ethanol. Forskolin was purchased from Cayman Chemical (Cat# 11018, Ann Arbor, MI), (R)‐BPO‐27 (Cat# HY‐19778), and CaCCinh A‐01 (Cat# HY‐100611) were from MedChemExpress

(15) Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and calciumJournal of Biological ChemistryMarch 1, 2025Shang-Jui Tsai, Yijing Gong, Austin Dabbs, Fiddia Zahra, Junhao Xu, Aleksander Geske, Michael J. Caterina, Stephen J. Gouldinhibitors, and antibodies A23187 (Sigma, C7522), ATP (Sigma, A26209), Forskolin (Cayman Chemical, 11018), H89 (MedChemExpress, HY-15979A), EGF (Gibco, PHG0311L), VX-11e (Selleckchem, S7709), leptomycin B

(16) eEF2K regulates pain through translational control of BDNFMolecular CellFebruary 20, 2025Patrick R. Smith, Guadalupe Garcia, Angela R. Meyer, Alexey G. Ryazanov, Tao Ma, Sarah Loerch, Zachary T. Campbell13697 GCN2iB,MedChemExpress,CAS No. 218347012-2; Cat No. HY-112654 Forskolin,Cayman Chemical,CAS No. 66575-299; Cat No.11018 Critical commercial assays,Critical commercial assays,Critical commercial assays Pierce™ BCA assay,Invitrogen,23225 Nano-Glo® Dual-Luciferase® Reporter Assay System

(17) VX-770, Cact-A1, and Increased Intracellular cAMP Have Distinct Acute Impacts upon CFTR ActivityInt J Mol SciJanuary 8, 2025Heidi J. Nick, Sarah E. Christeson, Preston E. Bratchereither DMSO alone (vehicle; #BP231-100, Fisher Chemical, Pittsburgh, PA, USA) or 10 µM forskolin (#11018, Cayman Chemical, Ann Arbor, MI, USA). Fischer rate thyroid (FRT) cells expressing normal CFTR were

(18) Protocol for generating a pancreatic cancer organoid associated with heterogeneous tumor microenvironmentSTAR ProtocJanuary 7, 2025Kenta Takeuchi, Shunsuke Tabe, Yuya Yamamoto, Kenta Takahashi, Megumi Matsuo, Yasuharu Ueno, Masayuki Ohtsuka, Soichiro Morinaga, Yohei Miyagi, Tomoyuki Yamaguchi, et al.Bio,Cat#DS-Y50053 CHIR99021,Cayman Chemical Company,Cat#13122 Forskolin,Cayman Chemical Company,Cat#11018 Accutase,Innnovative Cell Technologies Inc,Cat#AT104-500 iMatrix-511 silk,Matrixome,Cat#892021 "Poly-L-Lysine solution, 0.01

(19) A conserved transcription factor regulatory program promotes tendon fateDevelopmental CellDecember 1, 2024Xubo Niu, Delmy L. Melendez, Suyash Raj, Junming Cai, Dulanjalee Senadeera, Joseph Mandelbaum, Ilya A. Shestopalov, Scott D. Martin, Leonard I. Zon, Thorsten M. Schlaeger, et al.proteins","Chemicals, peptides, and recombinant proteins" ,, DMSO,Sigma,276855 Forskolin,Cayman Chemical,11018 Colforsin,Cayman Chemical,11214 8-Bromo-cAMP,Sigma,23583–48-4 IBMX,Cayman Chemical,13347 H-89,Cayman Chemical

(20) Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activationAmerican Journal of Physiology-Gastrointestinal and Liver PhysiologyDecember 1, 2024Michael Momoh, Sudiksha Rathan-Kumar, Andreanna Burman, Monica E. Brown, Francisca Adeniran, Cynthia Ramos, James R. Goldenring, Joseph T. Roland, Izumi Kajiusing the CFTR inhibitor (R)-Benzopyrimido-Pyrrolo-Oxazinedione (BPO)-27 (10 µM). Phlorizin, forskolin (11018; Cayman Chemical), and (R)-BPO-27 (HY-19778; MedChemExpress) were dissolved in DMSO as 1,000× stocks.

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Forskolin from Cayman Chemical

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Cayman Chemical

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Forskolin from Cayman Chemical

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