Mithramycin A from Cayman Chemical

Product Specs
ItemMithramycin A
CompanyCayman Chemical
Price $209.00Supplier Page View Company Product Page
Catalog Number11434
Quantity5 mg
Research AreaApoptosis, Cancer, Cell Death, Transcription Factors
FormatA crystalline solid
Molecular Weight1085.2
Purity≥98%
Storage-20
FormulaC52H76O24
OriginISR
TypeInhibitors

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Sp1 mechanotransduction regulates breast cancer cell invasion in engineered viscoelastic extracellular matricesBiomaterialsApril 1, 2026Abhishek Sharma, Rowan F. Steger, Jen M. Li, Samuel Y. Fong, Neha Saxena, Jane A. Baude, Kellie A. Heom, Siddharth S. Dey, Ryan S. Stowers0.1 μM for MDA-MB-231 cells, Cayman Chemical, #19166), and Mithramycin A (50 nM, Cayman Chemical, #11434). Inhibitor concentrations for ML-7 [19], Cytochalasin-D19, LY294002 [17,44], mithramycin-A17, and SCH772874

(2) Impact of histone post-translational modification inhibitors on lifespan, reproduction, and stress response in the rotifer Brachionus manjavacasPLoS OneOctober 29, 2025Nelia Luviano Aparicio, Meghan Dryburgh, Colleen M. McMaken, Alyssa Liguori, Kristin E. Gribbletesting β-hydroxybutyrate (#H6501, Sigma-Aldrich), sodium butyrate (#303410, Sigma-Aldrich) and mithramycin A (#11434, Cayman Chemical) were used to treat rotifers. Prior to conducting survivorship and reproduction assays,

(3) Deletion of EP3 prostaglandin receptor in murine macrophages aggravates diet-induced obesity by suppressing SPARCThe EMBO JournalJuly 23, 2025Wenlong Shang, Yinxiu Li, Lu Wang, Jiao Liu, Huiwen Ren, Qian Liu, Shumin Guo, Yuhong Wang, Yubo Ma, Tianyi You, et al.(#G6152) were purchased from Sigma-Aldrich (St. Louis, MO, USA). H-89 (#10010556) and Mithramycin A (#11434) were purchased from the Cayman Chemical Company (Ann Arbor, MI, USA). Palmitate acid and its solvent

(4) Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathwayFront Cell Dev BiolJuly 17, 2025Vida Maksimoska, Qinghong Dan, Neetu Rambharack, Katalin SzásziActinomycin D (Cat # 1229) were from Tocris Bioscience/Biotechne (Minneapolis, MN); Mithramycin A (Cat#11434) and Bay11-7085 (Cat#14795) from Cayman Chemicals (Ann Arbor, MI); SU5408 (Cat#103002) from MedChemExpress;

(5) Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axisNature cell biologyApril 1, 2024Murthy D, Attri KS, Shukla SK, Thakur R, Chaika NV, He C, Wang D, Jha K, Dasgupta A, King RJ, et al.SML0002), orlistat (Cayman, 10005426), ACSS2 inhibitor (Millipore, 533756), mithramycin A (Cayman, 11434), pentamidine (Cayman, 20679), 14C2-acetic acid, (Perkin Elmer, NEC553050UC), 2-deoxyglucose (Sigma-Aldrich,

(6) Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary HypertensionAntioxidants (Basel, Switzerland)December 29, 2022DeVallance ER, Dustin CM, de Jesus DS, Ghouleh IA, Sembrat JC, Cifuentes-Pagano E, Pagano PJ.USA). GLS1 inhibitor C-839 was purchased from EMD Millipore Corp (Burlington, MA, USA). Mithramycin A (11434) was purchased from Cayman Chemical (Ann Arbor, MI, USA). TransAM® Transcription Factor Activation Assay

(7) Mithramycin selectively attenuates DNA-damage-induced neuronal cell deathCell death & diseaseJuly 27, 2020Makarevich O, Sabirzhanov B, Aubrecht TG, Glaser EP, Polster BM, Henry RJ, Faden AI, Stoica BA.NY), doxorubicin (Cat. #CST-5927, Cell Signaling Technologies, Danvers, MA), and mithramycin (Cat. #11434, Cayman Chemical Company, Ann Arbor, MI) were used to treat 7 days in vitro (DIV) cells at concentrations

(8) IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency ReactivationCell host & microbeJune 12, 2019Hotter D, Bosso M, Jønsson KL, Krapp C, Stürzel CM, Das A, Littwitz-Salomon E, Berkhout B, Russ A, Wittmann S, et al.450,eBioscience,Cat# 65-0863-14 Benzonase Nuclease,Sigma-Aldrich,Cat# E1014-25KU Mithramycin A,Cayman Chemicals,Cat# 11434 MTT (Thiazolyl Blue Tetrazolium Bromide),Sigma-Aldrich,Cat# M5655 Critical Commercial Assays,Critical

(9) ZBP-89 and Sp1 contribute to Bak expression in hepatocellular carcinoma cellsBMC cancerApril 13, 2018Kong X, Xu P, Cai WJ, Wang HG, Li BB, Huang GL, He ZW, Chen G, Ye CG.JL Merchant (University of Michigan, MI) [11]. Mithramycin A (MMA) was purchase from Cayman Inc. (#11434-1 mg). All other chemicals and reagents were purchased from Sigma-Aldrich (St. Louis, MO) unless otherwise

(10) Tissue damage negatively regulates LPS-induced macrophage necroptosisCell death and differentiationSeptember 1, 2016Li Z, Scott MJ, Fan EK, Li Y, Liu J, Xiao G, Li S, Billiar TR, Wilson MA, Jiang Y, et al.and ferroptosis inhibitor Fer-1 (SML0583-5MG) was from Sigma-Aldrich. Sp1 inhibitor Mithramycin A (11434) was obtained from Cayman Chemical (Ann Arbor, MI, USA). Cdc42 inhibitor ML141 (sc-362768) was from

(11) The genomic context and co-recruitment of SP1 affect ERRα co-activation by PGC-1α in muscle cellsMolecular EndocrinologyJuly 1, 2016Silvia Salatino, Barbara Kupr, Mario Baresic, Saeed Omidi, Erik van Nimwegen, Christoph Handschinintramuscularly (i.m.) with either PBS + DMSO vehicle (30μl/TA) or Mithramycin A (Cayman Chemical, 11434) (1μg/TA) dissolved in DMSO in both TA muscles. Mice were sacrificed 6 hours post-injection and the

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Mithramycin A from Cayman Chemical

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Cayman Chemical

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Mithramycin A from Cayman Chemical

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