Description
A plecomacrolide antibiotic; active against S. cerevisiae, S. sake, A. citri, P. citrinum, and P. oryzae (MICs = 50 = ~2.1-2.3 µM); decreases perforin levels in CD8+ OE4 CTLs; inhibits concanavalin A-induced thymidine incorporation by 99% in isolated mouse splenic lymphocytes at 100 µM; prevents influenza virus entry into MDCK cells at 0.8 µM