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Palmitic Acid Alkyne
Palmitic Acid Alkyne from Cayman Chemical
Be the first to write a review!
Citations:
(18)
Supplier Page
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Cayman Chemical for
Palmitic Acid Alkyne
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Description
A form of palmitic acid with an ω-terminal alkyne for use in click chemistry to isolate palmitoylated proteins
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Palmitic Acid Alkyne
Company
Cayman Chemical
Price
$70.00
Supplier Page
View Company Product Page
Catalog Number
13266
Quantity
500 µg
Format
A crystalline solid
Research Area
Fatty Acids, Lipid Biochemistry, Protein Lipidation
Molecular Weight
252.4
Purity
≥95%
Storage
-20
Formula
C16H28O2
Origin
USA
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (18)
(1)
A bacterial family of fatty acid acyltransferases related to the Shigella effector IcsB
mBio
April 8, 2026
Waad Bajunaid, Kyle Tomaro, Anwer Hasil Kottarampatel, Geneviève F. Desrochers, Mathieu Lavallée-Adam, John P. Pezacki, François-Xavier Campbell-Valois
(
Cayman Chemical
,
17-octadecynoic acid
, also known as Alk-16 [#
90270
], myristic acid [#
13267
], palmitic acid [#
13266
], or oleic acid [#
9002078
]). Cells were incubated for 4 h and collected by
centrifugation
at 12,000
(2)
Lipid droplet-induced T cell death sustains autoimmune tissue inflammation
Cell Metabolism
April 7, 2026
Jitendra Kumar, Yoshinori Takashima, Jose Morales, Brandon Wong, Lina Werner, Isabel N. Goronzy, Selene Rubino, Robert T. Trousdale, Gerald J. Berry, Jörg J. Goronzy,
et al.
Blocking Solution (
S-1000-20
),
Vector Laboratories
,#
S-1000-20
"
Palmitic Acid Alkyne
, 1mg",
Cayman Chemical
,#
13266
Protein A/G PLUS-Agarose,SantaCruz Biotechnology,# sc-2003 "
TurboFect™ Transfection Reagent
,",
ThermoFisher
,#
R0531
SYTOX™ Green Nucleic Acid Stain - 5 mM Solution in DMSO
(3)
Structural basis and regulation of GSDME pore formation
Nature Communications
March 13, 2026
Evelyn Teran, Tian Tian, Chengliang Wang, Xinzheng Wang, Jinghan Wang, Dongchun Ni, Vijay A. Rathinam, Jianbin Ruan
transfection
, cells were treated with Alk-14 alkyne–palmitic acid (40 μM;
Cayman Chemical
, Cat. no.
13266
) for an additional 14 h in medium containing 10% charcoal-stripped FBS (
Thermo Fisher Scientific
, Cat.
(4)
Palmitoylation Induced Activation of SMAD3 Exacerbates Colitis by Promoting Tissue-resident Memory T Cells Differentiation
Inflammation
March 4, 2026
Yuejie Xu, Siqi Ji, Ping Jiang, Zhenguo Zhao, Qian Zhou, Dan Su, Shafi Ullah, Yu Zhao, Xiaoping Zou, Mingming Zhang,
et al.
NovaSeq XPLUS.
Click Chemistry
and In-gel
Fluorescence
Detection 50 µM palmitic acid alkyne 14 (Alk14) (
13266
,
Cayman Chemical
, Ann Arbor, MI, USA) were added to cells for 5 h and lysed in cold RIPA buffer (150
(5)
ASCT2 palmitoylation regulated by JNK1-ZDHHC14 axis orchestrates glutamine metabolism and NSCLC progression
Cell Discovery
February 24, 2026
Xingyu Chen, Zihao Ke, Shihui Wei, Jiajin Chen, Ke Zhu, Jiaqi Xu, Yun Zhao, Mengyuan Cen, Yan Jin, Zhilei Pan,
et al.
from
MedChemExpress
.
Palmitic acid sodium
(#E2900) was purchased from Selleck.
Palmitic Acid Alkyne
(#
13266
) was purchased from
Cayman Chemical
. Hydroxylamine solution (#438227), Tris ((1-benzyl-1H-1,2,3-triazol-4-yl)
(6)
Dietary fat disrupts a commensal-host lipid network that promotes metabolic health
Cell Metabolism
January 6, 2026
Kendra Klag, Darci Ott, Trevor S. Tippetts, Rebekah J. Nicolson, Sean M. Tatum, Kaylyn M. Bauer, Emmanuel Stephen-Victor, Allison M. Weis, Rickesha Bell, James Weagley,
et al.
E7850L
OCT,Fisher,Cat# 23-730.571
Palmitic acid
,
Sigma-Aldrich
,Cat# P5585
Palmitic acid alkyne
,
Cayman Chemical
,Cat#
13266
qScriptc DNA SuperMix,QuantaBio,Cat#101414-106 Scheadlers broth,Thermo Scientific,Cat# CM0497B SM
(7)
Dual Regulation of Sprouty 4 Palmitoylation by ZDHHC7 and Palmitoyl-Protein Thioesterase 1: A Potential Therapeutic Strategy for Cisplatin-Resistant Osteosarcoma
Research (Wash D C)
May 23, 2025
Tianlong Huang, Yifan Chen, Qiangqiang Zhao, Qiangqiang Zhao, Hongxing wu, Xin Luo, Yang Su, Shengqun Zhang, PAN LIU, Ning Tang
were treated with culture medium containing 20 μM alkynyl-palmitic acid (
Cayman Chemical
, Cat. No.
13266
) for 6 h to incorporate the alkyne group into the palmitoylated proteins, thereby providing reactive
(8)
Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes
Journal of Biological Chemistry
March 10, 2025
Michael G. Atser, Chelsea D. Wenyonu, Elyn M. Rowe, Connie L.K. Leung, Haoning Howard Cen, Eric D. Queathem, Leo T. Liu, Renata Moravcova, Jason Rogalski, David Perrin,
et al.
fatty acid fetal bovine serum, 1% antibiotic-antimycotic and 10 μM of palmitic acid alkyne (Cat. No.
13266
,
Cayman Chemical Company
) for 18 h after which they were placed in “
starvation
media” for 3 h with cells
(9)
Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis
Nat Commun
January 20, 2025
Bin Huang, Hui Wang, Shuo Liu, Meng Hao, Dan Luo, Yi Zhou, Ying Huang, Yong Nian, Lei Zhang, Bo Chu,
et al.
expression.
LC-MS analysis
of proteomics Cells treated with different conditions were incubated with 50 μM Alk14 (
13266
,
Cayman Chemical
) for 12 h and then collected and lysed in lysis buffer (100 mM Tris-HCl pH 7.2, 5 mM
(10)
The ORP9-ORP11 dimer promotes sphingomyelin synthesis
eLife
August 6, 2024
Cabukusta B, Borst Pauwels S, Akkermans JJLL, Blomberg N, Mulder AA, Koning RI, Giera M, Neefjes J.
sphingomyelin synthesis Cells were incubated with 20 µM ethanolic palmitic acid alkyne (
Cayman Chemical
#
13266
) in serum-free medium for 6 hr. Next, cells were washed twice in PBS and scraped in 2%NaCl solution.
(11)
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis
Science Immunology
April 12, 2024
Arumugam Balasubramanian, Alan Y. Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Dang Fabin, Hiroto Kambara,
et al.
Sigma-Aldrich
(St. Louis, MO).
Biotin HPDP
(
16459
), biotin azide (
13040
), and palmitic acid alkyne (
13266
) were purchased from
Cayman Chemical Company
(Bar Harbor, ME). The
click chemistry
protein reaction
(12)
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
Nature Cardiovascular Research
July 17, 2023
Maria N. Barrachina, Gerard Pernes, Isabelle C. Becker, Isabelle Allaeys, Thomas I. Hirsch, Dafna J. Groeneveld, Abdullah O. Khan, Daniela Freire, Karen Guo, Estelle Carminita,
et al.
depletion, cells were supplemented with fatty acids modified with a ω-terminal alkyne group (palmitic acid,
13266
; arachidonic acid,
10538
;
Cayman Chemical
). After 4 d of maturation,
click chemistry
was performed using
(13)
zDHHC9 Regulates Cardiomyocyte Rab3a Activity and Atrial Natriuretic Peptide Secretion Through Palmitoylation of Rab3gap1
JACC. Basic to translational science
May 1, 2023
Essandoh K, Subramani A, Ferro OA, Teuber JP, Koripella S, Brody MJ.
acid-free BSA (Sigma, A6003), with or without 100 μM palmitic acid alkyne (alk-14,
Cayman
Chemicals, #
13266
). Cells were then harvested in lysis buffer (25 mM Tris buffer pH 7.4, 150 mM NaCl, 2% SDS, 1% NP-40)
(14)
Click-chemistry-based protocol to quantitatively assess fatty acid uptake by Mycobacterium tuberculosis in axenic culture and inside mouse macrophages
STAR Protocols
March 1, 2023
Thomas Laval, Caroline Demangel
acids,
Cayman Chemical
,Cat#
10006627
;
90260
;
90010
;
90150
;
90110
;
90310
Alkyne fatty acids,
Cayman Chemical
,Cat#
13266
;
10541
;
9002078
;
10538
;
16704
;
16689
ProLong Diamond Antifade Mountant
,
Thermo Fisher Scientific
,Cat#
P36961
DAPI stain
(15)
Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage
Frontiers in Physiology
January 13, 2023
Fanny L. Lemarié, Shaun S. Sanders, Yen Nguyen, Dale D. O. Martin, Michael R. Hayden
acid),
Cayman Chemical
,#
13267
Fatty Acylation
Assays
,Click Tag
Palmitic Acid Alkyne
,
Cayman Chemical
,#
13266
Fatty Acylation
Assays
,
Cycloheximide
(CHX),
Millipore-Sigma
,#
C7698
Fatty Acylation
Assays
,Dulbecco’s
(16)
Regulation of Cell Polarity by Posttranslational Protein Palmitoylation
Methods in Molecular Biology
December 2, 2022
Baoen Chen, Carla Guarino, Abdelhalim Azzi, Hannah Erb, Xu Wu
reaction Dialyzed FBS (
Bio-Techne
, Cat. No.
S11150
).
Alk
-16C (15-hexadecynoic acid) (
Cayman Chemical
, Cat. No.
13266
), 50 mM in DMSO.Lysis buffer: 50 mM TEA-HCl (pH 7.4), 150 mM NaCl, 1%
Triton X-100
, 0.1% SDS, 1 mM
PMSF
,
(17)
Macrophage polarization state affects lipid composition and the channeling of exogenous fatty acids into endogenous lipid pools
The Journal of biological chemistry
December 1, 2021
Morgan PK, Huynh K, Pernes G, Miotto PM, Mellett NA, Giles C, Meikle PJ, Murphy AJ, Lancaster GI.
compared with fatty acids directly conjugated to a fluorophore. Alkyne-palmitate (
Cayman Chemical
, #
13266
) and alkyne-oleate (
Cayman Chemical
, #
9002078
) were initially solubilized in absolute ethanol and then
(18)
Detecting N-myristoylation and S-acylation of host and pathogen proteins in plants using click chemistry
Plant Methods
December 1, 2016
Patrick C. Boyle, Simon Schwizer, Sarah R. Hind, Christine M. Kraus, Susana De la Torre Diaz, Bin He, Gregory B. Martin
Protoplasts
were washed again and resuspended in the presence of the palmitic acid analog Alk14 (cat. no.
13266
,
Cayman Chemical
) at a final concentration of 10 μM. Cells were incubated for 6 h, collected, and stored at
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Palmitic Acid Alkyne from Cayman Chemical
Supplier Page
View Company Product Page
$70.00
Product Specs
Company Info
Citations
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