TGX-221 from Cayman Chemical

Product Specs
ItemTGX-221
CompanyCayman Chemical
Price $49.00Supplier Page View Company Product Page
Catalog Number10007349
Quantity1 mg
Research AreaBlood, Cardiovascular System, Cell Biology, Cell Signaling, Coagulation & Hemostasis, PI3K/Akt/mTOR Signaling, Thrombosis
FormatA crystalline solid
Molecular Weight364.4
Purity≥98%
Storage-20
FormulaC21H24N4O2
OriginUSA

Specifications/Features

Information:
phosphatidylinositol-3-kinases PI3K catalyzes phosphorylation produces second messengers (3,4)-biphosphates -P2 (3,4,5)-P3 Class 1 p110.alpha. .beta. .delta. .gamma. p85 regulatory subunits cells permeable inhibitors inhibition inhibits ATP binding sites platelets defective thrombus formation antithrombotic therapy

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistanceeLifeNovember 7, 2024Kim J, Kim D, Kim DK, Lee SH, Jang W, Lim DS.C10046), LY294002 (Sigma, L9908, used at 50 μM), VPS34-IN1 (Cayman, 17392, used at 5 μM), TGX-221 (Cayman, 10007349, used at 50 nM), GDC-0941 (Selleckchem, S1065, used at 100 nM), Dynasore (Sigma, D7693, used at 100

(2) Dominant Role of PI3K p110α over p110β in Insulin and β-Adrenergic Receptor SignallingInternational journal of molecular sciencesNovember 26, 2021Zhang B, Luk C, Valadares J, Aronis C, Foukas LC.was from Tocris/Bio-Techne (Minneapolis, MN, USA), PI3K p110β-selective inhibitor TGX221 (item no. 10007349), EPAC1 inhibitor CE3F4 (item no. 17767), and PKA inhibitor (PKI) fragment (2-22)-amide (item no. 17486)

(3) Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian EmbryogenesisDevelopmental cellApril 6, 2020Chi F, Sharpley MS, Nagaraj R, Roy SS, Banerjee U.,Cayman Chemical,Cat #11587 GDC0941 (0.5μM),Cayman Chemical,Cat #11600 TGX221 (0.5μM),Cayman Chemical,Cat #10007349 BX912 (100nM),Cayman Chemical,Cat #14708 GSK2334470 (50nM),Cayman Chemical,Cat #18095 MK2206 (200nM),Cayman Chemical

(4) Insulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytesThe Biochemical journalOctober 15, 2019Jönsson C, Castor Batista AP, Kjølhede P, Strålfors P.(A6730), wortmannin (W3144), A66 (SML1213), and 8-Br-cAMP (B7880) were from Sigma–Aldrich. TGX221 (10007349) was from Cayman Chem. (Ann Arbor, MI, U.S.A.). Torin-1 (#4247, Tocris Biosc. Oxford, U.K.), cilostamide (ab141273,

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TGX-221 from Cayman Chemical

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Specifications/Features

Cayman Chemical

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TGX-221 from Cayman Chemical

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