EUK 134 from Cayman Chemical

Product Specs
ItemEUK 134
CompanyCayman Chemical
Price $42.00Supplier Page View Company Product Page
Catalog Number10006329
Quantity5 mg
Research AreaAntioxidant Activity, Cardiovascular Diseases, Cardiovascular System, Catalase, Oxidative Stress & Reactive Species, Reactive Oxygen, Stroke, Superoxide Dismutase
FormatA crystalline solid
Molecular Weight416.7
Purity≥98%
Storage-20
FormulaC18H18ClMnN2O4
OriginCHN

Specifications/Features

Information:
salen manganese SOD ROS catalse stroke oxidative injury porphyrin scavengers peroxynitrites superoxides hydrogen peroxides arteries artery cerebral H2O2 infarct volumes

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Misprogramming of glucose metabolism impairs recovery of hippocampal slices from neuronal GLT‐1 knockout mice and contributes to excitotoxic injury through mitochondrial superoxide productionJournal of NeurochemistryJanuary 1, 2025S. Li, J. Wang, J. V. Andersen, B. I. Aldana, B. Zhang, E. V. Prochownik, P. A. Rosenbergcat. no. 71718), sodium D-lactate (Sigma Aldrich cat. no. 71716), EUK-134 (Cayman Chemical cat. no. 10006329), apocynin (Tocris cat. no. 4663), diphenylene iodonium (Sigma Aldrich cat. no. D2926), S1QEL1.1 (Sigma

(2) Inhibiting amyloid beta (1-42) peptide-induced mitochondrial dysfunction prevents the degradation of synaptic proteins in the entorhinal cortexFrontiers in aging neuroscienceJanuary 1, 2022Olajide OJ, La Rue C, Bergdahl A, Chapman CA.Toronto Research Chemicals; M372215), and SOD/catalase mimetic drug EUK134 (250 nM; Cayman Chemical; 10006329) during incubation of slices in hAβ1–42 or DMSO. Each treatment group included slices from at least

(3) Aerobic Conditions and Endogenous Reactive Oxygen Species Reduce the Production of Infectious MS2 Phage by Escherichia coliVirusesJuly 15, 2021Guillaume Bastin, Aurélie Galmiche, François Talfournier, Hortense Mazon, Julie Challant, Maëlle Robin, Didier Majou, Nicolas Boudaud, Christophe Gantzerapplicable, VAS-2870 (# BML-EI395 from Enzo Life Sciences, Farmingdale, New York, USA) and EUK-134 (#10006329 from Cayman Chemical, Ann Arbor, Michigan, USA) were added to the mixture containing the phages, E. coli

(4) Nox2 signaling and muscle fiber remodeling are attenuated by losartan administration during skeletal muscle unloadingPhysiological ReportsJanuary 5, 2021Jeffrey M. Hord, Marcela M. Garcia, Katherine R. Farris, Vinicius Guzzoni, Yang Lee, Matthew S. Lawler, John M. Lawlerdue to superoxide production, a superoxide dismutase mimetic (EUK‐134, 50µM, Cayman Chemical, cat # 10006329) was used to scavenge superoxide. In addition, pharmacological inhibitors were used to confirm that

(5) Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancerNatureFebruary 2, 2017Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, et al.and chemicals Trolox (Cat. No. 238813) and AICAR (A9978) were purchased from Sigma. EUK134 (Cat. No. 10006329) was purchased from Cayman Chemicals.13C and 15N labelled isotopes were purchased from Cambridge Isotope

(6) C. elegans Epidermal Wounding Induces a Mitochondrial ROS Burst that Promotes Wound RepairDevelopmental CellOctober 13, 2014Suhong Xu, Andrew D. Chisholmstock and allowed to dry for 1-2 h at room temperature. DPI (Sigma D2926), EUK-134 (Cayman Chemical 10006329) and Rotenone (Sigma R8875) were dissolved in DMSO to make 500 mM, 30 mM, 24 mM, and 40 mM stock solutions,

(7) Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECKJournal of cellular physiologyJuly 1, 2014Siddesha JM, Valente AJ, Sakamuri SS, Gardner JD, Delafontaine P, Noda M, Chandrasekar B.(#300260), SP600125 (#420119), and DMSO were purchased from EMD Biosciences (Gibbstown, NJ). EUK-134 (#10006329) is a synthetic manganese-porphyrin complex that scavenges reactive oxidative species such as H2O2,

(8) Hyperoxia and transforming growth factor β1 signaling in the post-ischemic mouse heartLife SciencesMarch 21, 2013Yuanjing Li, Ming Cai, Qinghua Sun, Zhenguo Liu, Arturo J. Cardounel, Harold M. Swartz, Guanglong Heconformed to the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. 10006329 EUK134 (EUK134, Cayman Chemical, Ann Arbor, MI) and sodium nitroprusside (SNP, Sigma-Aldrich, St. Louis,

(9) Formation of Hydrogen Peroxide and Reduction of Peroxynitrite via Dismutation of Superoxide at Reperfusion Enhances Myocardial Blood Flow and Oxygen Consumption in Postischemic Mouse HeartJournal of Pharmacology and Experimental TherapeuticsNovember 1, 2008Yi Xu, Bin Liu, Jay L. Zweier, Guanglong HeMethods Chemicals SODm is a gift from MetaPhore Pharmaceuticals (St. Louis, MO) (Masini et al., 2002). SODm, 10006329 EUK 134 (EUK134; Cayman Chemical, Ann Arbor, MI) (Izumi et al., 2002), and glibenclamide (Glib; Sigma-Aldrich,

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EUK 134

EUK 134

EUK 134 from Cayman Chemical

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Specifications/Features

Cayman Chemical

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EUK 134 from Cayman Chemical

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