PHOME from Cayman Chemical

Product Specs
ItemPHOME
CompanyCayman Chemical
Price $344.00Supplier Page View Company Product Page
Catalog Number10009134
Quantity10 mg
FormatA crystalline solid
Molecular Weight373.4
Purity≥98%
Storage-20
FormulaC23H19NO4
OriginUSA

Specifications/Features

Information:
sEH epoxides inhibitors inhibition inhibits substrates HTS

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Soluble epoxide hydrolase inhibitory constituents from the Heartwood of Toxicodendron vernicifluum: isolation, kinetic characterization, molecular modeling, and quantitative analysisScientific ReportsJanuary 20, 2026Jang Hoon Kim, Jae-Young Cheon, Jin Yu, Yong-Goo Kim, Sung Yeon Kim, Kyong-Hwan Bang, Jin Tae Jeong, Hyun-Ju Jung, Ik Soo Leeformic acid was purchased from Merck (St. Louis, MO, USA). Human recombinant sEH (10011669), PHOME (10009134), and AUDA (10007972) were from Cayman Chemical (Ann Arbor, MI, USA). Plant material T. vernicifluum

(2) Indirubin-3'-oxime as a dual-action agent: mitigating heat-induced male infertility in Drosophila melanogaster and inhibiting soluble epoxide hydrolaseJ Enzyme Inhib Med ChemJanuary 22, 2025Nguyen Viet Phong, Hyo-Sung Kim, Yan Zhao, Eunbyul Yeom, Seo Young Yangpurchased from Sigma-Aldrich (St. Louis, MO). sEH (human, recombinant; Item No. 10011669), PHOME (Item No. 10009134), and AUDA (Item No. 10007927) were purchased from Cayman Chemical (Ann Arbor, MI). Drosophila strain

(3) Inhibitory Activity of Glycosides from Elsholtzia ciliata against Soluble Epoxide Hydrolase and Cytokines in RAW264.7 CellsJournal of Microbiology and BiotechnologyNovember 11, 2024Jang Hoon Kim, Ji Hyeon Park, Kyung-Sook Han, Eun-Song Lee, Yong-Goo Kim, Yong-Il Kim, Sung Cheol Koo, Byoung Ok Chorecombinant sEH (10011669), 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME, 10009134), and AUDA (10007972) were achieved from Cayman Chemical (USA). Fetal bovine serum (FBS) and Dulbecco’s

(4) Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular DynamicsMarine DrugsAugust 17, 2024Nguyen Viet Phong, Nguyen Phuong Thao, Le Ba Vinh, Bui Thi Thuy Luyen, Chau Van Minh, Seo Young YangMarine Biochemistry, VAST. 4.2. Chemicals and Reagents sEH (human, recombinant; 10011669), PHOME (10009134), and AUDA (10007927) were purchased from Cayman Chemical (Ann Arbor, MI, USA). Bis-Tris (B9754) was

(5) The Inhibition Activity of Natural Methoxyflavonoid from Inula britannica on Soluble Epoxide Hydrolase and NO Production in RAW264.7 CellsInternational Journal of Molecular SciencesApril 15, 2024Jang Hoon Kim, Kyung-Sook Han, Eun-Song Lee, Yong-Goo Kim, Yong-Il Kim, Byoung Ok Cho, Ik Soo Leerecombinant sEH (10011669), 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME, 10009134), and AUDA (10007972) were purchased from Cayman Chemical (Ann Arbor, MI, USA). Greiss reagent and lipopolysaccharide

(6) Inhibitory Activity of Natural cis-Khellactone on Soluble Epoxide Hydrolase and Proinflammatory Cytokine Production in Lipopolysaccharides-Stimulated RAW264.7 CellsPlants (Basel)October 23, 2023Jang Hoon Kim, Ji Hyeon Park, Sung Cheol Koo, Yun-Chan Huh, Mok Hur, Woo Tae Park, Youn-Ho Moon, Tae Il Kim, Byoung Ok Choprofessional reagent store (Sigma-Aldrich, St. Louis, MO, USA). Mammalian recombinant sEH (10011669), PHOME (10009134), and AUDA (10007972) were sourced from Cayman Chemical (Ann Arbor, MI, USA). The Cell Viability Assay

(7) Anti-inflammatory of disenecionyl cis-khellactone in LPS-stimulated RAW264.7 cells and the its inhibitory activity on soluble epoxide hydrolaseHeliyonOctober 1, 2023Park JH, Kim JH, Jang SI, Cho BO.hydrolase (sEH, 10011669), cyano-(6-methoxynaphthalen-2-yl)methyl] 2-(3-phenyloxiran-2-yl)acetate (PHOME, 10009134), and 12-(3-((3s,5s,7s)-adamantan-1-yl)ureido)dodecanoic acid (AUDA, 10007972) were purchased from Cayman Chemical

(8) Inhibitory activity of lignanamides isolated from hemp seed hulls(Cannabis sativa L.) against soluble epoxide hydrolaseHeliyonSeptember 14, 2023Jang Hoon Kim, Yun-Chan Huh, Mok Hur, Woo Tae Park, Youn-Ho Moon, Tae IL. Kim, Seon Mi Kim, Sung-Cheol KooUSA). sEH (10011669), 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME, 10009134), and positive control (AUDA, 10007972) were purchased from Cayman Chemical (Ann Arbor, MI, USA). 2.2

(9) Inhibition of Soluble Epoxide Hydrolase Activity by Components of Glycyrrhiza uralensisInternational Journal of Molecular SciencesMarch 30, 2023Jang Hoon Kim, Yun-Chan Huh, Mok Hur, Woo Tae Park, Youn-Ho Moon, Tae Il Kim, Yong Il Kim, Seon Mi Kim, Jeonghoon Lee, Ik Soo Lee(A8806) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Human recombinant sEH (10011669), PHOME (10009134), and AUDA (10007972) were purchased from Cayman Chemical (Ann Arbor, MI, USA). 4.2. Extract Treatment Dried

(10) Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide HydrolaseCurrent Issues in Molecular BiologySeptember 16, 2022Jang Hoon Kim, Chong Woon Cho, Mok Hur, Woo Tae Park, Youn-Ho Moon, Sung-Cheol Koo, Yun-Chan Hur, Jong Seong Kang, Ik Soo Lee(479413-70-2), and 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME; 10009134) were purchased from Cayman Chemical (Ann Arbor, MI, USA). 2.2. sEH Enzymatic Assay The sEH assay

(11) Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of Ulmus davidiana var. japonicaJournal of Enzyme Inhibition and Medicinal ChemistryMay 18, 2021Jang Hoon Kim, Ji Su Park, Yun Ji Lee, Sena Choi, Young Ho Kim, Seo Young YangKyoto, Japan) were used for open column chromatography. sEH (10011669), AUDA (479413–70-2), and PHOME (10009134) were purchased from Cayman (Ann Arbour, Michigan, MO). Plant material The root bark of U. davidiana

(12) In Vitro and In Silico Studies of Soluble Epoxide Hydrolase Inhibitors from the Roots of Lycopus lucidusPlants (Basel)February 13, 2021Yoo Kyong Han, Ji Sun Lee, Seo Young Yang, Ki Yong Lee, Young Ho Kimn-BuOH, were purchased from SK chemical (Suwon, Gyeonggi-do, Korea). AUDA, sEH (10011669) and PHOME (10009134) were purchased from Cayman (Cayman, MI, USA.). 3.2. Plant Material The dried roots of L. lucidus

(13) Inhibitory Activity of Quercetin 3-O-Arabinofuranoside and 2-Oxopomolic Acid Derived from Malus domestica on Soluble Epoxide HydrolaseMoleculesSeptember 22, 2020In Sook Cho, Jang Hoon Kim, Yunjia Lin, Xiang Dong Su, Jong Seong Kang, Seo Young Yang, Young Ho Kim(10011669), and 3-phenyl-cyano(6-methoxy-2-naphthalenyl) methyl ester-2-oxiraneacetic acid (PHOME) (10009134) were purchased from Cayman (Cayman, Ann Arbor, MI, USA). 3.2. Plant Materials The fruits of M. domestica

(14) Coumarin and Moracin Derivatives from Mulberry Leaves (Morus alba L.) with Soluble Epoxide Hydrolase Inhibitory ActivityMoleculesAugust 31, 2020Hong Xu Li, Myungsook Heo, Younghoon Go, Young Soo Kim, Young Ho Kim, Seo Young Yang, Wei Li(sEH, 10011669), and 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME) (10009134) were purchased from the Cayman Chemical Company (Cayman, MI, USA). The 96-well white plate was purchased

(15) Inhibitory Activity of Flavonoids, Chrysoeriol and Luteolin-7-O-Glucopyranoside, on Soluble Epoxide Hydrolase from Capsicum chinenseBiomoleculesJanuary 24, 2020Jang Hoon Kim, Chang Hyun JinJapan) (Supplementary Materials). AUDA (10007927), soluble epoxide hydrolase (10011669) and PHOME (10009134) were purchased from Cayman (Cayman, Ann Arbor, MI, USA). 2.2. Plant Materials The leaves of C. chinense

(16) Inhibition potential of phenolic constituents from the aerial parts of Tetrastigma hemsleyanum against soluble epoxide hydrolase and nitric oxide synthaseJournal of enzyme inhibition and medicinal chemistryDecember 1, 2019Wang CY, Lee S, Jang HJ, Su XD, Wang HS, Kim YH, Yang SY.12 nm) and a SPD-20A wavelength detector at 210 nm. Soluble epoxide hydrolases (10011669) and PHOME (10009134) were purchased from Cayman (Cayman, MI, USA). Biological material The aerial parts of T. hemsleyanum

(17) Isolation of Two New Compounds and Other Constituents from Leaves of Piper crocatum and Study of Their Soluble Epoxide Hydrolase ActivitiesMoleculesJanuary 30, 2019Hong Xu Li, Seo Young Yang, Young Ho Kim, Wei LiAldrich (St. Louis, MO, USA). The human recombinant soluble epoxide hydrolases (sEH, 10011669), PHOME (10009134) and 12-(3-adamantan-1-yl-ureido)-dodecanoic acid (AUDA) (10007972) were purchased from Caymanchem (Cayman,

(18) In Vitro and In Silico Insights into sEH Inhibitors with Amide-Scaffold from the Leaves of Capsicum chinense JacqComputational and Structural Biotechnology JournalOctober 31, 2018Jang Hoon Kim, Yeong Deuk Jo, Hyo-Young Kim, Bo-Ram Kim, Bomi NamGermany) were used for the column chromatography. Soluble Epoxide Hydrolase Kit (10009658) and PHOME (10009134) were purchased from Cayman (MI, US). 2.2 Plant Material The leaves of C. chinense Jacq. cv. Habanero

(19) Soluble Epoxide Hydrolase Inhibitory Activity of Components Isolated from Apios americana MedikMoleculesAugust 30, 2017Jang Hoon Kim, Hyo Young Kim, Si Yong Kang, Young Ho Kim, Chang Hyun JinS-75 μm) resins were used for open column chromatography. AUDA (10007927), sEH (10011669), and PHOME (10009134) were purchased from Cayman (Cayman, Ann Arbor, MI, USA). 3.2. Plant Material In October 2016, the

(20) Soluble Epoxide Hydrolase Inhibitory Activity of Selaginellin Derivatives from Selaginella tamariscinaMoleculesDecember 2, 2015Jang Hoon Kim, Chong Woon Cho, Bui Huu Tai, Seo Young Yang, Gug-seoun Choi, Jong Seong Kang, Young Ho Kimmm ˆ 4.6 mm I.D.; 5 µm) column. Soluble epoxide hydrolases (human recombinant, 10011669) and PHOME (10009134) were purchased from Cayman (Ann Arbor, MI, USA). 3.2. Plant Material S. tamariscina was purchased from

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PHOME

PHOME

PHOME from Cayman Chemical

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Specifications/Features

Cayman Chemical

Citations (20)

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PHOME from Cayman Chemical

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