Description
An inhibitor of arginase types I and II; inhibits rat liver arginase I (Kis = 0.4 and 0.6 µM from kinetic analyses); inhibits human arginase II (Kis = 310 and 30 nM at pH 7.5 and 9.5, respectively); enhances nitric oxide-dependent relaxation of human penile corpus cavernosum smooth muscle in vitro at 0.1-1 mM