2-Cl-IB-MECA from Tocris Bioscience, a Bio-Techne Brand

Product Specs
Item2-Cl-IB-MECA
CompanyTocris Bioscience, a Bio-Techne Brand
Price $527.00Supplier Page View Company Product Page
Catalog Number1104/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight544.74
Molecule Name1-[2-Chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide
FormulaC18H18ClIN6O4
StorageDesiccate at +4°C

Sizes Available: 10 mg (also 50 mg)

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cellsExperimental eye researchMay 1, 2018Nakashima KI, Iwao K, Inoue T, Haga A, Tsutsumi T, Mochita MI, Fujimoto T, Tanihara H.

(3) Basal adenosine modulates the functional properties of AMPA receptors in mouse hippocampal neurons through the activation of A1R A2AR and A3RFrontiers in cellular neuroscienceJanuary 1, 2015Di Angelantonio S, Bertollini C, Piccinin S, Rosito M, Trettel F, Pagani F, Limatola C, Ragozzino D.

(4) Extracellular adenosine controls NKT-cell-dependent hepatitis inductionEuropean journal of immunologyApril 1, 2014Subramanian M, Kini R, Madasu M, Ohta A, Nowak M, Exley M, Sitkovsky M, Ohta A.

(5) Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma modelAmerican journal of cancer researchJanuary 1, 2014Iannone R, Miele L, Maiolino P, Pinto A, Morello S.

(6) Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemesEMBO reportsAugust 1, 2013Corriden R, Self T, Akong-Moore K, Nizet V, Kellam B, Briddon SJ, Hill SJ.

(9) High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell deathProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2012Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K.

(10) CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNSThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 29, 2012Rosito M, Deflorio C, Limatola C, Trettel F.

(11) Adoptive immunotherapy with Cl-IB-MECA-treated CD8+ T cells reduces melanoma growth in micePloS oneJanuary 1, 2012Montinaro A, Forte G, Sorrentino R, Luciano A, Palma G, Arra C, Adcock IM, Pinto A, Morello S.

(12) Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A(1) receptorsThe Journal of neuroscience : the official journal of the Society for NeuroscienceJuly 27, 2011Jinka TR, Tøien Ø, Drew KL.

(13) NK1.1 cells and CD8 T cells mediate the antitumor activity of Cl-IB-MECA in a mouse melanoma modelNeoplasia (New York, N.Y.)April 1, 2011Morello S, Sorrentino R, Montinaro A, Luciano A, Maiolino P, Ngkelo A, Arra C, Adcock IM, Pinto A.

(14) Inhibition of erythroblast growth and fetal hemoglobin production by ribofuranose-substituted adenosine derivativesBiochimica et biophysica actaSeptember 1, 2008Bhanu NV, Lee YT, Oneal PA, Gantt NM, Aerbajinai W, Noel P, Thomas CJ, Miller JL.

2-Cl-IB-MECA