PI 103 hydrochloride from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemPI 103 hydrochloride
CompanyTocris Bioscience, a Bio-Techne Brand
Price $140.00Supplier Page View Company Product Page
Catalog Number2930/1
Purity97%
Molecular Weight384.82
Molecule Name3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride
FormulaC19H16N4O3.HCl
StorageStore at +4°C
Quantity1 mg (also 10 mg)

Specifications/Features

Sizes Available: 1 mg (also 10 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Combinatorial pioneer transcription factor binding reinforces bivalent epigenetic states to preserve lineage fidelitybioRxivMay 26, 2026Gerardo Mirizio, Morgan Buckley, Katie Ludwig, Satoshi Matsui, Samuel Sampson, Hee-Woong Lim, Makiko IwafuchiShenandoah; or GFH6, Cell Guidance Systems), 2 μM CHIR99021 (SML1046–25MG, Sigma-Aldrich), and 50 nM PI103 (2930–1, Tocris Bioscience) for 24 h. For definitive endoderm (DE) induction, ME cells were briefly washed with

(2) Protocol for establishing inducible CRISPR interference system for multiple-gene silencing in human pluripotent stem cellsSTAR ProtocolsSeptember 20, 2024Satoshi Matsui, Joseph R. Shiley, Marissa Granitto, Katie Ludwig, Morgan Buckley, Sandra Koigi, Gerardo Mirizio, Yueh-Chiang Hu, Christopher N. Mayhew, Makiko IwafuchiSystems,Cat# 800-0Cat# GFH6 CHIR99021,Sigma-Aldrich,Cat# SML1046-25MG PI-103,Tocris Bioscience,Cat# 2930-1 LDN193189,Sigma-Aldrich,Cat# SML0559-5MG A83-01,Sigma-Aldrich,Cat# SML0788-5MG ATRA,Sigma-Aldrich,Cat#

(3) Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm DevelopmentCell reportsApril 16, 2019Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R.

(4) Capacitation of human naïve pluripotent stem cells for multi-lineage differentiationDevelopment (Cambridge, England)April 3, 2019Rostovskaya M, Stirparo GG, Smith A.

(5) Epigenetic resetting of human pluripotencyDevelopment (Cambridge, England)August 1, 2017Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, et al.

(6) Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting β(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligandsPloS oneJanuary 1, 2015Rider CF, Shah S, Miller-Larsson A, Giembycz MA, Newton R.

(7) Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysisJournal of virologyNovember 1, 2014Brown MC, Dobrikov MI, Gromeier M.

(8) Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesodermStem CellsJune 1, 2014Engels MC, Rajarajan K, Feistritzer R, Sharma A, Nielsen UB, Schalij MJ, de Vries AA, Pijnappels DA, Wu SM.

(9) Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cellsThe Journal of experimental medicineJanuary 13, 2014Li C, Lee PS, Sun Y, Gu X, Zhang E, Guo Y, Wu CL, Auricchio N, Priolo C, Li J, et al.

(10) Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosisPloS oneJanuary 1, 2014Li C, Zhang E, Sun Y, Lee PS, Zhan Y, Guo Y, Osorio JC, Rosas IO, Xu KF, Kwiatkowski DJ, et al.

(11) ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning changeJournal of experimental botanyNovember 1, 2013Montané MH, Menand B.

(12) P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironmentsPloS oneJanuary 1, 2013Campbell AD, Lawn S, McGarry LC, Welch HC, Ozanne BW, Norman JC.

(13) The transcriptional regulator NAB2 reveals a two-step induction of TRAIL in activated plasmacytoid DCsEuropean journal of immunologyNovember 1, 2012Balzarolo M, Karrich JJ, Engels S, Blom B, Medema JP, Wolkers MC.

(14) Platelet-derived growth factor CC-mediated neuroprotection against HIV Tat involves TRPC-mediated inactivation of GSK 3betaPloS oneJanuary 1, 2012Peng F, Yao H, Akturk HK, Buch S.

(15) A screen for regulators of survival of motor neuron protein levelsNature chemical biologyJune 19, 2011Makhortova NR, Hayhurst M, Cerqueira A, Sinor-Anderson AD, Zhao WN, Heiser PW, Arvanites AC, Davidow LS, Waldon ZO, Steen JA, et al.

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