Nutlin-3 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemNutlin-3
CompanyTocris Bioscience, a Bio-Techne Brand
Price $393.00Supplier Page View Company Product Page
Catalog Number3984/10
Quantity10 mg
Purity98%
Molecular Weight581.49
Molecule Name(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
FormulaC30H30Cl2N4O4
StorageStore at -20°C

Specifications/Features

Sizes Available: 10 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Mesenchymal Stem Cells Increase Drug Tolerance of A431 Cells Only in 3D Spheroids, Not in 2D Co-CulturesInternational Journal of Molecular SciencesApril 20, 2024Flóra Vajda, Áron Szepesi, Zsuzsa Erdei, Edit Szabó, György Várady, Dániel Kiss, László Héja, Katalin Német, Gergely Szakács, András FürediKorea). Cisplatin (Cat. No: Vnr461201) was obtained from Accord Healthcare, UK; nutlin-3 (Cat. No: 3984/10) was obtained from Tocris Bioscience (Bristol, UK). 4.5. Flow Cytometry Analysis Cells were seeded

(2) Comparison of Different Clinical Chemotherapeutical Agents' Toxicity and Cell Response on Mesenchymal Stem Cells and Cancer CellsCellsSeptember 20, 2022Vajda F, Szepesi Á, Várady G, Sessler J, Kiss D, Erdei Z, Szebényi K, Német K, Szakács G, Füredi A.

(3) Replication stress promotes cell elimination by extrusionNatureMay 1, 2021Dwivedi VK, Pardo-Pastor C, Droste R, Kong JN, Tucker N, Denning DP, Rosenblatt J, Horvitz HR.

(4) Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathwayLife science allianceSeptember 1, 2020Gerakopoulos V, Ngo P, Tsiokas L.

(5) Discovery and characterization of highly potent and selective allosteric USP7 inhibitorsNature chemical biologyFebruary 1, 2018Gavory G, O'Dowd CR, Helm MD, Flasz J, Arkoudis E, Dossang A, Hughes C, Cassidy E, McClelland K, Odrzywol E, et al.

(6) The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survivalDevelopment (Cambridge, England)January 3, 2018Norlin S, Parekh V, Edlund H.

(7) p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cellsNucleic acids researchNovember 2, 2017Periyasamy M, Singh AK, Gemma C, Kranjec C, Farzan R, Leach DA, Navaratnam N, Pálinkás HL, Vértessy BG, Fenton TR, et al.

(8) A redox mechanism underlying nucleolar stress sensing by nucleophosminNature communicationsNovember 25, 2016Yang K, Wang M, Zhao Y, Sun X, Yang Y, Li X, Zhou A, Chu H, Zhou H, Xu J, et al.

(9) Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinomaClinical and translational medicineMarch 1, 2016Bussey KJ, Bapat A, Linnehan C, Wandoloski M, Dastrup E, Rogers E, Gonzales P, Demeure MJ.

(10) Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid LeukemiaClinical cancer research : an official journal of the American Association for Cancer ResearchFebruary 1, 2016Seipel K, Marques MT, Bozzini MA, Meinken C, Mueller BU, Pabst T.

(11) Small molecule induced reactivation of mutant p53 in cancer cellsNucleic acids researchJuly 1, 2013Liu X, Wilcken R, Joerger AC, Chuckowree IS, Amin J, Spencer J, Fersht AR.

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Nutlin-3

Nutlin-3 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (11)

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Nutlin-3 from Tocris Bioscience, a Bio-Techne Brand

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