Salubrinal from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemSalubrinal
CompanyTocris Bioscience, a Bio-Techne Brand
Price $282.00Supplier Page View Company Product Page
Catalog Number2347/10
Purity98%
Molecular Weight479.81
Molecule Name3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide
FormulaC21H17N4OSCl3
StorageStore at +4°C
Quantity10 mg

Specifications/Features

Sizes Available: 10 mg

Add to Compare List

Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased LethalityFrontiers in Cardiovascular MedicineMarch 18, 2020Hamid el Azzouzi, Andreia P. Vilaça, Dries A. M. Feyen, Willemijn M. Gommans, Roel A. de Weger, Pieter A. F. Doevendans, Joost P. G. Sluijtereither treated with indicated combinations of BrefeldinA (Sigma #B7651) 0.5 μg/ml, Salubrinal (Tocris #2347) 10 μM or vehicle. Forty-eight hours after transfection, cells were lysed for western blot analysis or fixed

(2) Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione BiosynthesisInternational journal of molecular sciencesOctober 29, 2018Wang SF, Wung CH, Chen MS, Chen CF, Yin PH, Yeh TS, Chang YL, Chou YC, Hung HH, Lee HC.

(3) Inhibitory Effects of Dopamine Receptor D(1) Agonist on Mammary Tumor and Bone MetastasisScientific reportsApril 4, 2017Minami K, Liu S, Liu Y, Chen A, Wan Q, Na S, Li BY, Matsuura N, Koizumi M, Yin Y, et al.

(4) mTORC1 and CK2 coordinate ternary and eIF4F complex assemblyNature communicationsApril 4, 2016Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, Tenkerian C, Morita M, Balanathan P, Jean-Jean O, et al.

(5) Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the GutJournal of immunology (Baltimore, Md. : 1950)May 15, 2015Sodhi CP, Jia H, Yamaguchi Y, Lu P, Good M, Egan C, Ozolek J, Zhu X, Billiar TR, Hackam DJ.

(6) Chondroprotective effects of Salubrinal in a mouse model of osteoarthritisBone & joint researchMay 1, 2015Hamamura K, Nishimura A, Iino T, Takigawa S, Sudo A, Yokota H.

(7) Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapyHepatology internationalJanuary 1, 2015Vandewynckel YP, Laukens D, Bogaerts E, Paridaens A, Van den Bussche A, Verhelst X, Van Steenkiste C, Descamps B, Vanhove C, Libbrecht L, et al.

(8) Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell deathACS chemical biologyDecember 19, 2014Tran K, Li Y, Duan H, Arora D, Lim HY, Wang W.

(9) Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flowPloS oneJanuary 1, 2014Wan Q, Xu W, Yan JL, Yokota H, Na S.

(10) Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytesJournal of musculoskeletal & neuronal interactionsSeptember 1, 2013Shim JW, Hamamura K, Chen A, Wan Q, Na S, Yokota H.

(11) Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanismBloodJuly 25, 2013Hahn CK, Lowrey CH.

(12) Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potentialLaboratory investigation; a journal of technical methods and pathologyApril 1, 2013Gu L, Johno H, Nakajima S, Kato H, Takahashi S, Katoh R, Kitamura M.

(13) Inhibitors of eIF2α dephosphorylation slow replication and stabilize latency in Toxoplasma gondiiAntimicrobial agents and chemotherapyApril 1, 2013Konrad C, Queener SF, Wek RC, Sullivan WJ Jr.

(14) Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasionThe Journal of biological chemistryAugust 17, 2012Shrestha N, Bahnan W, Wiley DJ, Barber G, Fields KA, Schesser K.

(15) Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin BThe Journal of biological chemistryApril 1, 2011Bergeron MJ, Bürzle M, Kovacs G, Simonin A, Hediger MA.

(16) Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cellsCell death & diseaseSeptember 9, 2010Bennett HL, Fleming JT, O'Prey J, Ryan KM, Leung HY.