BMS 493 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemBMS 493
CompanyTocris Bioscience, a Bio-Techne Brand
Price $306.00Supplier Page View Company Product Page
Catalog Number3509/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight404.5
Molecule Name4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoic acid
FormulaC29H24O2
StorageStore at +4°C

Sizes Available: 10 mg (also 50 mg)

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Induction of primordial germ cell-like cells from common marmoset embryonic stem cells by inhibition of WNT and retinoic acid signalingScientific reportsFebruary 23, 2023Shono M, Kishimoto K, Hikabe O, Hayashi M, Semi K, Takashima Y, Sasaki E, Kato K, Hayashi K.and 10 μM ROCK inhibitor with or without 2.5 μM IWR1 (TOCRIS, #3532) and 1.0 µM BMS493 (R&D Systems, #3509/10). In each well, 5 × 103 cells were used. In the experiments requiring enforced expression of the transgenes,

(2) Retinoic acid inhibitors mitigate vision loss in a mouse model of retinal degenerationScience advancesMarch 18, 2022Telias M, Sit KK, Frozenfar D, Smith B, Misra A, Goard MJ, Kramer RH.

(3) Tenogenic Induction From Induced Pluripotent Stem Cells Unveils the Trajectory Towards Tenocyte DifferentiationFrontiers in cell and developmental biologyJanuary 1, 2022Yoshimoto Y, Uezumi A, Ikemoto-Uezumi M, Tanaka K, Yu X, Kurosawa T, Yambe S, Maehara K, Ohkawa Y, Sotomaru Y, et al.

(4) Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarctioneLifeOctober 8, 2021Da Silva F, Jian Motamedi F, Weerasinghe Arachchige LC, Tison A, Bradford ST, Lefebvre J, Dolle P, Ghyselinck NB, Wagner KD, Schedl A.

(5) Capture of Mouse and Human Stem Cells with Features of Formative PluripotencyCell stem cellMarch 4, 2021Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo GG, Dietmann S, Nichols J, Smith A.

(6) Local retinoic acid signaling directs emergence of the extraocular muscle functional unitPLoS biologyNovember 1, 2020Comai GE, Tesařová M, Dupé V, Rhinn M, Vallecillo-García P, da Silva F, Feret B, Exelby K, Dollé P, Carlsson L, et al.

(7) Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regenerationEBioMedicineOctober 1, 2020Zhao L, Son JS, Wang B, Tian Q, Chen Y, Liu X, de Avila JM, Zhu MJ, Du M.

(8) Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune SuppressionCellMarch 19, 2020Devalaraja S, To TKJ, Folkert IW, Natesan R, Alam MZ, Li M, Tada Y, Budagyan K, Dang MT, Zhai L, et al.

(9) Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem CellsStem cells internationalJanuary 1, 2020Wang J, Li G, Hu L, Yan F, Zhao B, Wu X, Zhang C, Wang J, Du J, Wang S.

(10) Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene ExpressionStructure (London, England : 1993)August 6, 2019Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, et al.

(12) A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident MacrophagesImmunityJuly 16, 2019Buechler MB, Kim KW, Onufer EJ, Williams JW, Little CC, Dominguez CX, Li Q, Sandoval W, Cooper JE, Harris CA, et al.

(13) Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the SkinCell host & microbeJune 12, 2019Harris TA, Gattu S, Propheter DC, Kuang Z, Bel S, Ruhn KA, Chara AL, Edwards M, Zhang C, Jo JH, et al.

(14) A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the AdultImmunityMay 21, 2019Al Nabhani Z, Dulauroy S, Marques R, Cousu C, Al Bounny S, Déjardin F, Sparwasser T, Bérard M, Cerf-Bensussan N, Eberl G.

(15) Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiationEBioMedicineOctober 1, 2018Ng-Blichfeldt JP, Schrik A, Kortekaas RK, Noordhoek JA, Heijink IH, Hiemstra PS, Stolk J, Königshoff M, Gosens R.

(16) Anti-inflammatory effects of minocycline are mediated by retinoid signalingBMC neuroscienceSeptember 21, 2018Clemens V, Regen F, Le Bret N, Heuser I, Hellmann-Regen J.

(17) RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiationDevelopment (Cambridge, England)August 2, 2018Metzler MA, Raja S, Elliott KH, Friedl RM, Tran NQH, Brugmann SA, Larsen M, Sandell LL.

(18) Higher-Order Kidney Organogenesis from Pluripotent Stem CellsCell stem cellDecember 7, 2017Taguchi A, Nishinakamura R.

(19) Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureterScientific reportsNovember 1, 2017Bohnenpoll T, Weiss AC, Labuhn M, Lüdtke TH, Trowe MO, Kispert A.

(20) A Gene Regulatory Network Balances Neural and Mesoderm Specification during Vertebrate Trunk DevelopmentDevelopmental cellMay 8, 2017Gouti M, Delile J, Stamataki D, Wymeersch FJ, Huang Y, Kleinjung J, Wilson V, Briscoe J.

BMS 493