Cycloheximide from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemCycloheximide
CompanyTocris Bioscience, a Bio-Techne Brand
Price $110.00Supplier Page View Company Product Page
Catalog Number0970/100
Quantity100 mg
Purity97%
Molecular Weight281.35
Molecule Name4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
FormulaC15H23NO4
StorageDesiccate at RT

Specifications/Features

Sizes Available: 100 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) De novo design of a peptide modulator to reverse sodium channel dysfunction linked to cardiac arrhythmias and epilepsyCellOctober 30, 2025Ryan Mahling, Bence Hegyi, Erin R. Cullen, Timothy M. Cho, Aaron R. Rodriques, Lucile Fossier, Marc Yehya, Lin Yang, Bi-Xing Chen, Alexander N. Katchman, et al.proteins" ELIXIR-cpp,This Paper,N/A Ranolazine,Sigma Aldrich,Cat#R6152 Cycloheximide,Tocris,Cat#0970/100 Experimental models: Cell lines,Experimental models: Cell lines,Experimental models: Cell lines Human:

(2) Transition between cell states of sensitivity reveals molecular vulnerability of drug-tolerant cellsMolecular Systems BiologyOctober 1, 2025Ludovic Peyre, Marielle Péré, Mickael Meyer, Benjamin Bian, Marina Moureau-Barbato, Walid Djema, Bernard Mari, Georges Vassaux, Jérémie Roux#V5265 NSA,Calbiochem,Cat #432531-71-0 BV6,Calbiochem,Cat #5.33965 Cycloheximide,R&D systems Europe,Cat #0970-100 Recombinant human TRAIL,R&D systems Europe,Cat #375-TEC DMEM,Life Technologies,Cat #10569010 McCoy’s

(3) NGF-Dependent and BDNF-Dependent DRG Sensory Neurons Deploy Distinct Degenerative Signaling MechanismseneuroJanuary 1, 2021Andrés de León, Julien Gibon, Philip A. Barker(final concentration of DMSO below 0.1%). The translation inhibitor cycloheximide (CHX; R&D Systems 0970/100) was dissolved at 1.0 g/l in water and used at 1:1000. Autophagy inhibitor 3-methyladenine (3-MA; Sigma-Aldrich

(4) AMPK activation regulates P-body dynamics in mouse sensory neurons in vitro and in vivoNeurobiology of pain (Cambridge, Mass.)January 1, 2019Paige C, Mejia G, Dussor G, Price T.

(5) Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levelsCell communication and signaling : CCSOctober 4, 2018Zhang X, Zhao Y, Wang C, Ju H, Liu W, Zhang X, Miao S, Wang L, Sun Q, Song W.

(6) Staufen1 links RNA stress granules and autophagy in a model of neurodegenerationNature communicationsSeptember 7, 2018Paul S, Dansithong W, Figueroa KP, Scoles DR, Pulst SM.

(7) Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signalingExperimental & molecular medicineJune 6, 2018Shin W, Lee SK, Hwang JH, Park JC, Cho YH, Ro EJ, Song Y, Seo HR, Choi KY.

(8) USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilizationNature communicationsMarch 29, 2018Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, Zhang Q, Yu N, Ding X, Yang F, et al.

(9) Nongenomic Glucocorticoid Suppression of a Postsynaptic Potassium Current via Emergent Autocrine Endocannabinoid Signaling in Hypothalamic Neuroendocrine Cells following Chronic DehydrationeNeuroSeptember 1, 2017Wu N, Tasker JG.

(10) Acute Stress Suppresses Synaptic Inhibition and Increases Anxiety via Endocannabinoid Release in the Basolateral AmygdalaThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 10, 2016Di S, Itoga CA, Fisher MO, Solomonow J, Roltsch EA, Gilpin NW, Tasker JG.

(11) A balance of positive and negative regulators determines the pace of the segmentation clockeLifeSeptember 10, 2015Wiedermann G, Bone RA, Silva JC, Bjorklund M, Murray PJ, Dale JK.

(12) Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticityThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 4, 2015Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, Baudry M.

(13) Phosphorylation and degradation of tomosyn-2 de-represses insulin secretionThe Journal of biological chemistrySeptember 5, 2014Bhatnagar S, Soni MS, Wrighton LS, Hebert AS, Zhou AS, Paul PK, Gregg T, Rabaglia ME, Keller MP, Coon JJ, et al.

(14) Opioid receptor function is regulated by post-endocytic peptide processingThe Journal of biological chemistryJuly 11, 2014Gupta A, Gomes I, Wardman J, Devi LA.

(15) A molecular brake controls the magnitude of long-term potentiationNature communicationsJanuary 1, 2014Wang Y, Zhu G, Briz V, Hsu YT, Bi X, Baudry M.

(16) Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizuresNeurobiology of diseaseNovember 1, 2013Bernard PB, Castano AM, O'Leary H, Simpson K, Browning MD, Benke TA.

(17) Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depressionPloS oneJanuary 1, 2013Ramiro-Cortés Y, Israely I.

(18) Oxytocin-stimulated NFAT transcriptional activation in human myometrial cellsMolecular endocrinology (Baltimore, Md.)October 1, 2012Pont JN, McArdle CA, López Bernal A.

(19) Dual regulation of fragile X mental retardation protein by group I metabotropic glutamate receptors controls translation-dependent epileptogenesis in the hippocampusThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 12, 2011Zhao W, Chuang SC, Bianchi R, Wong RK.

(20) Pharmacological and genetic accumulation of hypoxia-inducible factor-1alpha enhances excitatory synaptic transmission in hippocampal neurons through the production of vascular endothelial growth factorThe Journal of neuroscience : the official journal of the Society for NeuroscienceApril 28, 2010Huang YF, Yang CH, Huang CC, Tai MH, Hsu KS.

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Cycloheximide

Cycloheximide

Cycloheximide from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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Cycloheximide from Tocris Bioscience, a Bio-Techne Brand

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