TCS 1102 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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TCS 1102

Potent, dual orexin receptor antagonist

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Tocris Bioscience, a Bio-Techne Brand for
TCS 1102

Description

Potent, dual orexin receptor antagonist

Product Specs
ItemTCS 1102
CompanyTocris Bioscience, a Bio-Techne Brand
Price $233.00Supplier Page View Company Product Page
Catalog Number3818/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight470.59
Molecule NameN-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl-2-pyrrolidinedicarboxamide
FormulaC27H26N4O2S
StorageStore at RT

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Circadian regulation of developmental synaptogenesis via the hypocretinergic systemNature communicationsJune 2, 2023Du XF, Li FN, Peng XL, Xu B, Zhang Y, Li G, Liu T, Li Y, Wang H, Yan J, et al.

(2) Orexin Modulation of VTA Dopamine Neuron Activity: Relevance to SchizophreniaThe international journal of neuropsychopharmacologyApril 21, 2021Perez SM, Lodge DJ.

(3) The dual orexin receptor antagonist TCS1102 does not affect reinstatement of nicotine-seekingPloS oneJanuary 1, 2017Khoo SY, McNally GP, Clemens KJ.

(4) Promotion of Wakefulness and Energy Expenditure by Orexin-A in the Ventrolateral Preoptic AreaSleepSeptember 1, 2015Mavanji V, Perez-Leighton CE, Kotz CM, Billington CJ, Parthasarathy S, Sinton CM, Teske JA.

(5) Blocking of orexin receptors in the paraventricular nucleus of the thalamus has no effect on the expression of conditioned fear in ratsFrontiers in behavioral neuroscienceJanuary 1, 2015Dong X, Li Y, Kirouac GJ.

(6) Calcium affects OX1 orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machineryBritish journal of pharmacologyDecember 1, 2014Putula J, Pihlajamaa T, Kukkonen JP.

(7) Orexinergic activation of medullary premotor neurons modulates the adrenal sympathoexcitation to hypothalamic glucoprivationDiabetesJune 1, 2014Korim WS, Bou Farah L, McMullan S, Verberne AJ.

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