NF 449 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemNF 449
CompanyTocris Bioscience, a Bio-Techne Brand
Price $309.00Supplier Page View Company Product Page
Catalog Number1391/10
Quantity10 mg (also 50 mg)
Molecular Weight1505.06
Molecule Name4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid, octasodium salt
FormulaC41H24N6Na8O29S8
Purity90%
StorageStore at RT

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formationScience advancesNovember 19, 2021Oda Y, Takahashi C, Harada S, Nakamura S, Sun D, Kiso K, Urata Y, Miyachi H, Fujiyoshi Y, Honigmann A, et al.(036-20601, Wako), P. multocida (01-507, BioAcademia), pertussis toxin (168-22471, Fujifilm/Wako), NF-449 (1391/10, R&D Systems), and YM-254890 (257-000631, Fujifilm/Wako). Peptide treatment Synthetic peptides were

(2) Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assaysScientific reportsNovember 2, 2020Su L, Bryan N, Battista S, Freitas J, Garabedian A, D'Alessio F, Romano M, Falanga F, Fusco A, Kos L, et al.

(3) Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonismScientific reportsOctober 7, 2019Johansson KE, Ståhl AL, Arvidsson I, Loos S, Tontanahal A, Rebetz J, Chromek M, Kristoffersson AC, Johannes L, Karpman D.

(4) Decoy Receptor Interactions as Novel Drug Targets against EKC-Causing Human AdenovirusVirusesMarch 12, 2019Chandra N, Frängsmyr L, Arnberg N.

(5) Characterization of purinergic receptor expression in ARPKD cystic epitheliaPurinergic signallingDecember 1, 2018Palygin O, Ilatovskaya DV, Levchenko V, Klemens CA, Dissanayake L, Williams AM, Pavlov TS, Staruschenko A.

(6) Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertilityeLifeFebruary 2, 2018Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, et al.

(7) Research articleHemolysis in human erythrocytes by Clostridium perfringens epsilon toxin requires activation of P2 receptorsVirulenceJanuary 1, 2018Gao J, Xin W, Huang J, Ji B, Gao S, Chen L, Kang L, Yang H, Shen X, Zhao B, et al.

(8) Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphinScientific reportsMarch 22, 2017Li TF, Wu HY, Wang YR, Li XY, Wang YX.

(9) Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 ExpressionTheranosticsJanuary 1, 2017Li X, Chen W, Li P, Wei J, Cheng Y, Liu P, Yan Q, Xu X, Cui Y, Gu Z, et al.

(10) The role of adenosine diphosphate mediated platelet responsiveness for the stability of platelet integrity in citrated whole blood under ex vivo conditionsPloS oneJanuary 1, 2017Koessler J, Schwarz M, Weber K, Etzel J, Koessler A, Boeck M, Kobsar A.

(11) Role of Purinergic Receptor Expression and Function for Reduced Responsiveness to Adenosine Diphosphate in Washed Human PlateletsPloS oneJanuary 1, 2016Koessler J, Hermann S, Weber K, Koessler A, Kuhn S, Boeck M, Kobsar A.

(12) The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan SulfatePLoS pathogensOctober 1, 2015Nishimura Y, McLaughlin NP, Pan J, Goldstein S, Hafenstein S, Shimizu H, Winkler JD, Bergelson JM.

(13) Optodynamic simulation of β-adrenergic receptor signallingNature communicationsSeptember 28, 2015Siuda ER, McCall JG, Al-Hasani R, Shin G, Il Park S, Schmidt MJ, Anderson SL, Planer WJ, Rogers JA, Bruchas MR.

(14) Effects of NAD at purine receptors in isolated blood vesselsPurinergic signallingMarch 1, 2015Alefishat E, Alexander SP, Ralevic V.

(15) The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastomaNature medicineSeptember 1, 2014He X, Zhang L, Chen Y, Remke M, Shih D, Lu F, Wang H, Deng Y, Yu Y, Xia Y, et al.

(16) Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and βBiopolymersSeptember 1, 2014Madoux F, Tredup C, Spicer TP, Scampavia L, Chase PS, Hodder PS, Fields GB, Becker-Pauly C, Minond D.

(17) The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivoEmerging microbes & infectionsSeptember 1, 2014Ren P, Zou G, Bailly B, Xu S, Zeng M, Chen X, Shen L, Zhang Y, Guillon P, Arenzana-Seisdedos F, et al.

(18) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruliAmerican journal of physiology. Cell physiologyNovember 15, 2013Ilatovskaya DV, Palygin O, Levchenko V, Staruschenko A.

(19) Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7CirculationJanuary 29, 2013Vergani A, Tezza S, D'Addio F, Fotino C, Liu K, Niewczas M, Bassi R, Molano RD, Kleffel S, Petrelli A, et al.

(20) Overexpression of CD39 in mouse airways promotes bacteria-induced inflammationJournal of immunology (Baltimore, Md. : 1950)August 15, 2012Théâtre E, Frederix K, Guilmain W, Delierneux C, Lecut C, Bettendorff L, Bours V, Oury C.

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NF 449

NF 449 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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NF 449 from Tocris Bioscience, a Bio-Techne Brand

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