Simvastatin from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemSimvastatin
CompanyTocris Bioscience, a Bio-Techne Brand
Price $264.00Supplier Page View Company Product Page
Catalog Number1965/50
Purity98%
Molecular Weight418.57
Molecule Name(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate
FormulaC25H38O5
StorageDesiccate at -20°C
Quantity50 mg

Specifications/Features

Sizes Available: 50 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) HIV-TAT dysregulates microglial lipid metabolism through SREBP2/miR-124 axis: Implication of lipid droplet accumulation microglia in NeuroHIVBrain, Behavior, and ImmunityJanuary 1, 2025Yan Cheng, Jaekeun Jung, Liyang Guo, Dorela D. Shuboni-Mulligan, Jian-Fu Chen, Wenhui Hu, Ming-Lei GuoThe working solution was diluted to 2 μM. Simvastatin (SIM) was purchased for Tocris company (Cat# 1965/50) and prepared as previously mentioned [39]. In brief, 50 mg SIM was dissolved in 1 ml ethanol and 1.5

(2) An in vivo brain–bacteria interface: the developing brain as a key regulator of innate immunitynpj Regenerative MedicineDecember 1, 2020Celia Herrera-Rincon, Jean-Francois Paré, Christopher J. Martyniuk, Sophia K. Jannetty, Christina Harrison, Alina Fischer, Alexandre Dinis, Vishal Keshari, Richard Novak, Michael LevinNI Xenopus embryos were treated with 0.4 μM Simvastatin (Supplementary Fig. S1h–j; Tocris Cat. No. 1965/50) for 18 h at 22 °C. After 18-h exposure, embryos were transferred to fresh normal media (0.1X MMR) and

(3) Apigenin in the regulation of cholesterol metabolism and protection of blood vesselsExperimental and therapeutic medicineMay 1, 2017Zhang K, Song W, Li D, Jin X.

(4) Chemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasisPloS oneJanuary 1, 2014Rojo-Arreola L, Long T, Asarnow D, Suzuki BM, Singh R, Caffrey CR.

(5) Acute simvastatin inhibits K ATP channels of porcine coronary artery myocytesPloS oneJanuary 1, 2013Seto SW, Au AL, Poon CC, Zhang Q, Li RW, Yeung JH, Kong SK, Ngai SM, Wan S, Ho HP, et al.

(6) Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statinsOncotargetDecember 1, 2011Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, et al.

(7) Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cellsBritish journal of pharmacologyAugust 1, 2007Seto SW, Au AL, Lam TY, Chim SS, Lee SM, Wan S, Tjiu DC, Shigemura N, Yim AP, Chan SW, et al.

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Simvastatin

Simvastatin from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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Simvastatin from Tocris Bioscience, a Bio-Techne Brand

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