CGP 37157 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemCGP 37157
CompanyTocris Bioscience, a Bio-Techne Brand
Price $290.00Supplier Page View Company Product Page
Catalog Number1114/10
Purity98%
Molecular Weight324.22
Molecule Name7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
FormulaC15H11Cl2NOS
StorageStore at RT
Quantity10 mg (also 50 mg)

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Distinct properties of Ca(2+) efflux from brain, heart and liver mitochondria: The effects of Na(+), Li(+) and the mitochondrial Na(+)/Ca(2+) exchange inhibitor CGP37157Cell calciumJune 1, 2021Rysted JE, Lin Z, Walters GC, Rauckhorst AJ, Noterman M, Liu G, Taylor EB, Strack S, Usachev YM.SET). CGP37157, forskolin, SB431542, IWP2, DAPT and LDN193189 were purchased from Tocris (Biotechne; 1114–10 mg). Fura-2A/M (F1201) and Calcium Green 5-N (C3737) were purchased from Thermofisher. Percoll was purchased

(2) Cyclophilin D counterbalances mitochondrial calcium uniporter-mediated brain mitochondrial calcium uptakeBiochemical and biophysical research communicationsAugust 20, 2020Zhang B, Jia K, Tian J, Du H.μmol each stroke). 1 μM Cyclosporin A (CsA, Sigma-Aldrich, C3662), 1μM CGP-37157 (Tocris Bioscience, 1114/10) and/or 0.01nM, 0.1nM, 1nM,10nM and 10 μM Ru360 (Millipore, 557440) was preincubated with mitochondria

(3) Analysis of predicted proteasomal cleavages in the methyltransferase domain from JEVBioinformationMarch 31, 2020Sarah Afaq, Arshi Malik, Md Salman Akhtar, Afaf S Alwabli, Dhafer A Alzahrani, Habeeb M Al-Solami, Othman Alzahrani, Qamre Alam, Mohammad Azhar Kamal, Aala A Abulfaraj, et al.vaccines, 2011 10:563 [PMID: 21604976]. [2] Cleaves G.R. and D.T. Dubin Virology, 1979 96:159 [PMID: 111410]. [3] Wengler G. & Wengler G, Virology, 1981 113:544 [PMID: 7269253]. [4] Lindenbach BD The viruses

(4) Paraneoplastic cerebellar degeneration: Yo antibody alters mitochondrial calcium buffering capacityNeuropathology and applied neurobiologyFebruary 1, 2019Panja D, Vedeler CA, Schubert M.

(5) Selective inhibition of mitochondrial sodium-calcium exchanger protects striatal neurons from α-synuclein plus rotenone induced toxicityCell death & diseaseJanuary 28, 2019Bastioli G, Piccirillo S, Castaldo P, Magi S, Tozzi A, Amoroso S, Calabresi P.

(6) Routes of Ca2+ Shuttling during Ca2+ Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca2+ HANDLING AND CYTOSOLIC Ca2+ BUFFERSThe Journal of biological chemistryNovember 20, 2015Pecze L, Blum W, Schwaller B.

(7) Mitochondrial Ca²⁺ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector functioneLifeMay 14, 2015Yang R, Lirussi D, Thornton TM, Jelley-Gibbs DM, Diehl SA, Case LK, Madesh M, Taatjes DJ, Teuscher C, Haynes L, et al.

(8) Palmitoylethanolamide inhibits glutamate release in rat cerebrocortical nerve terminalsInternational journal of molecular sciencesMarch 11, 2015Lin TY, Lu CW, Wu CC, Huang SK, Wang SJ.

(9) Dynamic buffering of mitochondrial Ca2+ during Ca2+ uptake and Na+-induced Ca2+ releaseJournal of bioenergetics and biomembranesJune 1, 2013Blomeyer CA, Bazil JN, Stowe DF, Pradhan RK, Dash RK, Camara AK.

(10) Na delivery and ENaC mediate flow regulation of collecting duct endothelin-1 productionAmerican journal of physiology. Renal physiologyMay 15, 2012Pandit MM, Strait KA, Matsuda T, Kohan DE.

(11) High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell deathProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2012Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K.

(12) Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondriaCellular and molecular life sciences : CMLSMarch 1, 2011Zhdanov AV, Dmitriev RI, Papkovsky DB.

(13) Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathwaysPloS oneJanuary 1, 2011Midkiff J, Borochoff-Porte N, White D, Johnson DI.

(14) Target cell-specific involvement of presynaptic mitochondria in post-tetanic potentiation at hippocampal mossy fiber synapsesThe Journal of neuroscience : the official journal of the Society for NeuroscienceDecember 12, 2007Lee D, Lee KH, Ho WK, Lee SH.

(15) Involvement of mitochondrial Na+-Ca2+ exchange in intestinal pacemaking activityWorld journal of gastroenterologyFebruary 7, 2006Kim BJ, Jun JY, So I, Kim KW.

(16) Na+-dependent sources of intra-axonal Ca2+ release in rat optic nerve during in vitro chemical ischemiaThe Journal of neuroscience : the official journal of the Society for NeuroscienceOctober 26, 2005Nikolaeva MA, Mukherjee B, Stys PK.

(17) Brain mitochondria are primed by moderate Ca2+ rise upon hypoxia/reoxygenation for functional breakdown and morphological disintegrationThe Journal of biological chemistryJuly 11, 2003Schild L, Huppelsberg J, Kahlert S, Keilhoff G, Reiser G.

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CGP 37157

CGP 37157 from Tocris Bioscience, a Bio-Techne Brand

Description

Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (17)

Reviews

CGP 37157 from Tocris Bioscience, a Bio-Techne Brand

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