BIO from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemBIO
CompanyTocris Bioscience, a Bio-Techne Brand
Price $243.00Supplier Page View Company Product Page
Catalog Number3194/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight356.17
Molecule Name(2'Z,3'E)-6-Bromoindirubin-3'-oxime
FormulaC16H10BrN3O2
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafishPLoS geneticsNovember 1, 2024Coppola U, Saha B, Kenney J, Waxman JS.treatments were: 1 μM RA (Sigma R2625), 2.5 μM DEAB (Sigma-Aldrich, Cat # D86256), 5 μM BIO (Tocris, Cat # 3194), 10 μM XAV939 (Tocris, Cat # 3748), 75 μM CYA (Sigma-Aldrich, Cat # C4116), 10 μM SAG (Tocris, Cat # 4366).

(2) Transcriptome, proteome, and protein synthesis within the intracellular cytomatrixiScienceFebruary 17, 2023Shaiken TE, Grimm SL, Siam M, Williams A, Rezaeian AH, Kraushaar D, Ricco E, Robertson MJ, Coarfa C, Jain A, et al.Torin 1,Tocris Bioscience,Cat# 4247/10 PF4708671,Tocris Bioscience,Cat# 4032/5 Bio,Tocris Bioscience,Cat# 3194/10 Rotenone,Tocris Bioscience,Cat# 3616/50 MG132,Tocris Bioscience,Cat# 1748/5 Geldanamycin,Tocris Bioscience,Cat#

(3) Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T CellsCell reportsMarch 26, 2019Fleskens V, Minutti CM, Wu X, Wei P, Pals CEGM, McCrae J, Hemmers S, Groenewold V, Vos HJ, Rudensky A, et al.

(4) Trypanosoma cruzi Exploits Wnt Signaling Pathway to Promote Its Intracellular Replication in MacrophagesFrontiers in immunologyJanuary 1, 2018Volpini X, Ambrosio LF, Fozzatti L, Insfran C, Stempin CC, Cervi L, Motran CC.

(5) Myotome adaptability confers developmental robustness to somitic myogenesis in response to fibre number alterationDevelopmental biologyNovember 15, 2017Roy SD, Williams VC, Pipalia TG, Li K, Hammond CL, Knappe S, Knight RD, Hughes SM.

(6) MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic FluxCell stem cellOctober 5, 2017Cliff TS, Wu T, Boward BR, Yin A, Yin H, Glushka JN, Prestegaard JH, Dalton S.200 ng/mL LONG® R3 human IGF-I, 8 ng/mL human basic-FGF, 20 µM SB431542 and 0.2 µM BIO (R&D Systems, 3194/10). Media was changed every 24 hr. Positive expression of PAX3, SOX1 and SOX2 via qRT-PCR, immunofluorescence

(7) TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial CellsCancer cellMay 8, 2017Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V, et al.

(8) Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programsDevelopment (Cambridge, England)April 1, 2017Stevens ML, Chaturvedi P, Rankin SA, Macdonald M, Jagannathan S, Yukawa M, Barski A, Zorn AM.

(9) Wnt signalling is a bi-directional vulnerability of cancer cellsOncotargetSeptember 13, 2016Duffy DJ, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, Haley B, Whilde J, Haapa-Paananen S, Fey V, et al.

(10) A High-content screen identifies compounds promoting the neuronal differentiation and the midbrain dopamine neuron specification of human neural progenitor cellsScientific reportsNovember 6, 2015Rhim JH, Luo X, Xu X, Gao D, Zhou T, Li F, Qin L, Wang P, Xia X, Wong ST.

(11) A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destructioneLifeSeptember 22, 2015Pronobis MI, Rusan NM, Peifer M.

(12) GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosisPLoS biologyApril 1, 2015Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, Zhang C.

(13) Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signalingStem cells translational medicineMarch 1, 2015Efthymiou AG, Steiner J, Pavan WJ, Wincovitch S, Larson DM, Porter FD, Rao MS, Malik N.

(14) Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephroneLifeFebruary 3, 2015Lindström NO, Lawrence ML, Burn SF, Johansson JA, Bakker ER, Ridgway RA, Chang CH, Karolak MJ, Oxburgh L, Headon DJ, et al.

(15) GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferationCell cycle (Georgetown, Tex.)January 1, 2015Penas C, Mishra JK, Wood SD, Schürer SC, Roush WR, Ayad NG.

(16) GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitorsNature chemical biologyJanuary 1, 2015Thorne CA, Wichaidit C, Coster AD, Posner BA, Wu LF, Altschuler SJ.

(17) Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/β-catenin pathwayNature communicationsNovember 5, 2014Lu FI, Sun YH, Wei CY, Thisse C, Thisse B.

(18) Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitorsBMC research notesApril 29, 2014Naujok O, Lentes J, Diekmann U, Davenport C, Lenzen S.

(19) PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesisLeukemiaMarch 1, 2014Berger A, Hoelbl-Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, Uras IZ, Menzl I, Putz EM, Hoermann G, et al.

(20) GSK3 inhibitors regulate MYCN mRNA levels and reduce neuroblastoma cell viability through multiple mechanisms, including p53 and Wnt signalingMolecular cancer therapeuticsFebruary 1, 2014Duffy DJ, Krstic A, Schwarzl T, Higgins DG, Kolch W.

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BIO

BIO from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

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BIO from Tocris Bioscience, a Bio-Techne Brand

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