TRAM 34 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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TRAM 34

Potent and highly selective KCa3.1 (IK) channel blocker

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Tocris Bioscience, a Bio-Techne Brand for
TRAM 34

Description

Potent and highly selective KCa3.1 (IK) channel blocker

Product Specs
ItemTRAM 34
CompanyTocris Bioscience, a Bio-Techne Brand
Price $203.00Supplier Page View Company Product Page
Catalog Number2946/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight344.84
Molecule Name1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
FormulaC22H17ClN2
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Oral Intake of EPA:DHA 6:1 by Middle-Aged Rats for One Week Improves Age-Related Endothelial Dysfunction in Both the Femoral Artery and Vein: Role of CyclooxygenasesInternational journal of molecular sciencesJanuary 30, 2020Gaertner S, Auger C, Farooq MA, Pollet B, Khemais-Benkhiat S, Niazi ZR, Schrevens S, Park SH, Toti F, Stephan D, et al.

(2) Functional Cooperation between KCa3.1 and TRPV4 Channels in Bronchial Smooth Muscle Cell Proliferation Associated with Chronic AsthmaFrontiers in pharmacologyJanuary 1, 2017Yu Z, Wang Y, Qin L, Chen H.

(3) 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat heartsJournal of biomedical scienceJune 16, 2015Chien CC, Su MJ.

(4) Piezo1 links mechanical forces to red blood cell volumeeLifeMay 22, 2015Cahalan SM, Lukacs V, Ranade SS, Chien S, Bandell M, Patapoutian A.

(5) Estrogen receptor subtypes mediate distinct microvascular dilation and reduction in [Ca2+]I in mesenteric microvessels of female ratThe Journal of pharmacology and experimental therapeuticsFebruary 1, 2015Mazzuca MQ, Mata KM, Li W, Rangan SS, Khalil RA.

(6) Enhanced K(+) secretion in dextran sulfate-induced colitis reflects upregulation of large conductance apical K(+) channels (BK; Kcnma1)American journal of physiology. Cell physiologyNovember 1, 2013Kanthesh BM, Sandle GI, Rajendran VM.

(7) Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somataJournal of neurophysiologyMay 1, 2013Benton MD, Lewis AH, Bant JS, Raman IM.

(8) TRAM-34, a putatively selective blocker of intermediate-conductance, calcium-activated potassium channels, inhibits cytochrome P450 activityPloS oneJanuary 1, 2013Agarwal JJ, Zhu Y, Zhang QY, Mongin AA, Hough LB.

(9) Intermediate conductance calcium-activated potassium channels modulate summation of parallel fiber input in cerebellar Purkinje cellsProceedings of the National Academy of Sciences of the United States of AmericaFebruary 14, 2012Engbers JD, Anderson D, Asmara H, Rehak R, Mehaffey WH, Hameed S, McKay BE, Kruskic M, Zamponi GW, Turner RW.

(10) Norepinephrine causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+EndocrinologyOctober 1, 2011Zemkova H, Stojilkovic SS, Klein DC.

(11) Relaxin causes selective outward remodeling of brain parenchymal arterioles via activation of peroxisome proliferator-activated receptor-γFASEB journal : official publication of the Federation of American Societies for Experimental BiologySeptember 1, 2011Chan SL, Cipolla MJ.

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