PD 0325901 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemPD 0325901
CompanyTocris Bioscience, a Bio-Techne Brand
Price $378.00Supplier Page View Company Product Page
Catalog Number4192/10
Quantity10 mg (also 50 mg)
Purity99%
Molecular Weight482.19
Molecule NameN-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
FormulaC16H14F3IN2O4
StorageStore at -20°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) A multi-kingdom genetic barcoding system for precise clone isolationNature BiotechnologyMay 21, 2025Soh Ishiguro, Kana Ishida, Rina C. Sakata, Minori Ichiraku, Ren Takimoto, Rina Yogo, Yusuke Kijima, Hideto Mori, Mamoru Tanaka, Samuel King, et al.0), consisting of NDiff 227 (Takara Bio, no. Y40002) supplemented with 1 µM PD0325901 (Tocris, no. 4192), 10 ng ml−1 Recombinant Human LIF (Peprotech, no. 300-05), 1 mM valproic acid (Sigma-Aldrich, no. P4543)

(2) Efficient Reprogramming of Mouse Embryonic Stem Cells into Trophoblast Stem-like Cells via Lats Kinase InhibitionBiology (Basel)January 24, 2024Yake Gao, Wenrui Han, Rui Dong, Shu Wei, Lu Chen, Zhaolei Gu, Yiming Liu, Wei Guo, Fang YanGermany, ESG1107) or hLIF (PeproTech, Cranbury, NJ, USA, 300-05), 1 μM PD0325901 (Tocris, Bristol, UK, 4192/10), and 3 μM CHIR99021 (Tocris, 4423/10). The N2B27 basal medium was prepared by mixing DMEM/F-12 (Gibco,

(3) Automated, High‐Throughput Phenotypic Screening and Analysis Platform to Study Pre‐ and Post‐Implantation Morphogenesis in Stem Cell‐Derived Embryo‐Like StructuresAdvanced ScienceJanuary 1, 2024Vinidhra Shankar, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht(SB43),Tgfβ (ALK) Inhibitor,Abcam ab120163,10 µm PD0325901 (PD032),MEK/ERK Inhibitor,Bio‐Techne Sales corp 4192/10,1 µm PD98059 (PD98),Fgf/MAPK Inhibitor,SelleckChem S1177,10 µm Fgf4 + heparin,Fgf/MAPK activator,R&D

(4) Stimulation of GHRH Neuron Axon Growth by Leptin and Impact of Nutrition during Suckling in MiceNutrientsFebruary 21, 2023Decourtye-Espiard L, Clemessy M, Leneuve P, Mire E, Ledent T, Le Bouc Y, Kappeler L.

(5) Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cellsNature communicationsDecember 3, 2022Gerdes P, Lim SM, Ewing AD, Larcombe MR, Chan D, Sanchez-Luque FJ, Walker L, Carleton AL, James C, Knaupp AS, et al.

(6) The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cellseLifeJuly 11, 2022Ávila-González D, Portillo W, Barragán-Álvarez CP, Hernandez-Montes G, Flores-Garza E, Molina-Hernández A, Díaz-Martínez NE, Díaz NF.

(7) Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation developmentNature communicationsJuly 5, 2022Mau KHT, Karimlou D, Barneda D, Brochard V, Royer C, Leeke B, de Souza RA, Pailles M, Percharde M, Srinivas S, et al.

(8) Streamlined and quantitative detection of chimerism using digital PCRScientific reportsJune 17, 2022Suchy FP, Nishimura T, Seki S, Wilkinson AC, Higuchi M, Hsu I, Zhang J, Bhadury J, Nakauchi H.containing 20 ng/ml human LIF (Peprotech, Cranbury, NJ; 300-05), 1 uM PD0325901 (Tocris, Minneapolis, MN; 4192-10) and 3 µM CHIR99021 (Tocris, Minneapolis, MN; 4423/10). Outgrowths were picked and dissociated before

(9) Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinctionScientific reportsMarch 8, 2022Zywitza V, Rusha E, Shaposhnikov D, Ruiz-Orera J, Telugu N, Rishko V, Hayashi M, Michel G, Wittler L, Stejskal J, et al.

(10) Optimized protocol for naive human pluripotent stem cell-derived trophoblast inductionSTAR protocolsDecember 17, 2021Io S, Iemura Y, Takashima Y.

(11) Hyperglycemia Altered DNA Methylation Status and Impaired Pancreatic Differentiation from Embryonic Stem CellsInternational journal of molecular sciencesOctober 3, 2021Chen ACH, Huang W, Fong SW, Chan C, Lee KC, Yeung WSB, Lee YL.

(12) Generation of mouse-human chimeric embryosNature protocolsAugust 1, 2021Zhang B, Li H, Hu Z, Jiang H, Stablewski AB, Marzullo BJ, Yergeau DA, Feng J.

(13) Capturing human trophoblast development with naive pluripotent stem cells in vitroCell stem cellJune 3, 2021Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, Wang B, Okamoto I, Nakamura T, Kojima Y, et al.

(14) Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiationNature communicationsMay 13, 2021Lee HH, Wang YN, Yang WH, Xia W, Wei Y, Chan LC, Wang YH, Jiang Z, Xu S, Yao J, et al.#1744/10), GSK1120212 (1 nM, Apexbio Technology, #A301850), PD-0325901 (0.2 or 2 μM, Tocris Bioscience, #4192/10), MK-2206 (20 nM, Apexbio Technology, #A301010), and Dasatinib (2 nM, LC Laboratories, #D-3307). Plasmids

(15) Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosisNature communicationsApril 23, 2021Ferreira APA, Casamento A, Carrillo Roas S, Halff EF, Panambalana J, Subramaniam S, Schützenhofer K, Chan Wah Hak L, McGourty K, Thalassinos K, et al.

(16) Cell Surface Mechanics Gate Embryonic Stem Cell DifferentiationCell stem cellFebruary 4, 2021Bergert M, Lembo S, Sharma S, Russo L, Milovanović D, Gretarsson KH, Börmel M, Neveu PA, Hackett JA, Petsalaki E, et al.

(17) TENET: gene network reconstruction using transfer entropy reveals key regulatory factors from single cell transcriptomic dataNucleic acids researchJanuary 11, 2021Kim J, T Jakobsen S, Natarajan KN, Won KJ.

(18) The histone demethylase KDM2B regulates human primordial germ cell-like cells specificationInternational journal of biological sciencesJanuary 1, 2021Yuan W, Yao Z, Veerapandian V, Yang X, Wang X, Chen D, Ma L, Li C, Zheng Y, Luo F, et al.

(19) Gastruloids: Embryonic Organoids from Mouse Embryonic Stem Cells to Study Patterning and Development in Early Mammalian EmbryosMethods in molecular biology (Clifton, N.J.)January 1, 2021Anlas K, Baillie-Benson P, Arató K, Turner DA, Trivedi V.

(20) Bisphenol A Induces Agrp Gene Expression in Hypothalamic Neurons through a Mechanism Involving ATF3NeuroendocrinologyJanuary 1, 2021Loganathan N, McIlwraith EK, Belsham DD.(cat. SML0309100MG) were purchased from MilliporeSigma, and SP600125 (cat. 1496/10) and PD0352901 (cat. 4192/10) were purchased from Tocris Bioscience (Cedarlane, Burlington, ON, Canada). 5-aminoimidazole-4-carboxamide

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PD 0325901

PD 0325901

PD 0325901 from Tocris Bioscience, a Bio-Techne Brand

Description

Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (58)

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PD 0325901 from Tocris Bioscience, a Bio-Techne Brand

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