Forskolin from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemForskolin
CompanyTocris Bioscience, a Bio-Techne Brand
Price $224.00Supplier Page View Company Product Page
Catalog Number1099/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight410.51
Molecule Name(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
FormulaC22H34O7
StorageStore at -20°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) The anti-inflammatory efficacy of melanocortin drugs is influenced by genetic variation at MC1RScientific ReportsJune 11, 2026Natalya Khodeneva, Camilla S. A. Davan-Wetton, Thomas E. N. Jonassen, Mauro Perretti, Trinidad Montero-Melendez3-isobutyl-1-methylxanthine (IBMX, Sigma-Aldrich, St. Louis, USA, Cat#I5879), forskolin (Tocris Bioscience, Cat#1099/10), lipopolysaccharide from E. coli O111:B4 (Sigma-Aldrich, Cat#L2630), ibuprofen sodium salt (Sigma-Aldrich,

(2) Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell linesCell Reports MethodsApril 20, 2026Adam Pavlinek, Sara Guerrisi, Kara O'Driscoll, Lucia Dutan Polit, Roland Nagy, APEX consortium, Madeline A. Lancaster, Anthony C. Vernon, Deepak P. Srivastavatreatment consisted of Rolipram (Tocris; 0905/10), stock prepared as 25 mM in DMSO, and Forskolin (Tocris; 1099/10), stock prepared as 50 mM in DMSO. On the day of treatment, a full medium change with 600 μL media per

(3) Development, Expansion, and Histological Characterization of Patient-Derived Liver Organoids for Drug Screening and Disease ModelingBIO-PROTOCOLMarch 5, 2026Silvia De Siervi, Stefania Mantovani, Barbara Oliviero, Mario U. Mondelli, Martina Di Noia, Cristiana Soldani, Barbara Franceschini, Fabrizio De Luca, Marcello Maestri, Salvatore Corallo, et al.FGF-19, recombinant human (Peprotech, catalog number: 100-32) 11. Forskolin (Tocris, catalog number: 1099/10) 12. Gastrin I human (Leu15) (Sigma-Aldrich, catalog number: G9145) 13. GlutaMAXTM supplement (Gibco,

(4) Development, Expansion, and Histological Characterization of Patient-Derived Liver Organoids for Drug Screening and Disease ModelingBio ProtocMarch 5, 2026Silvia De Siervi, Stefania Mantovani, Barbara Oliviero, Mario U. Mondelli, Martina Di Noia, Cristiana Soldani, Barbara Franceschini, Fabrizio De Luca, Marcello Maestri, Salvatore Corallo, et al.FGF-19, recombinant human (Peprotech, catalog number: 100-32) 11. Forskolin (Tocris, catalog number: 1099/10) 12. Gastrin I human (Leu15) (Sigma-Aldrich, catalog number: G9145) 13. GlutaMAXTM supplement (Gibco,

(5) Modulation of striatal cAMP levels: A key pathway in the treatment of hyperkinetic movement disordersiScienceFebruary 20, 2026Yuan R, Roze E, Doulazmi M, Dubacq C, Longueville S, Delmas M, Khelaifia B, Micaux J, Nakamura Y, Romanato M, et al.(No.1063/10), selective D1R agonist SKF81297 (No.1447/10) and AC activator (including AC5) Forskolin (No.1099/10) were purchased from Tocris. Istradefylline, caffeine, and CGS21680, used in investigating locomotion

(6) Global reorganization of genome architecture at the transition to gametogenesisNature Structural & Molecular BiologyFebruary 20, 2026Tien-Chi Huang, Maria Rigau, Valeriya Malysheva, Chad Whilding, Stella Siciliani, Jingyu Li, Irina Balaguer Balsells, Pavel Artemov, Camille Dion, Mikhail Spivakov, et al.amino acids, 2 mM glutamine, 0.1 mM β-mercaptoethanol, 100 ng ml−1 SCF, 10 µM forskolin (R&D system, 1099/10), 10 µM rolipram (StemCell Technologies, 73384), penicillin–streptomycin (Gibco, 15140122). All cells

(7) Epigenetic regulation by HDAC11-driven STAT3 activation promotes pro-inflammatory cytokine production and endothelial dysfunction upon bacterial infection in diabetesCell Communication and SignalingFebruary 10, 2026Wiwit Ananda Wahyu Setyaningsih, Hojjat Naderi-Meshkin, Andrew Yacoub, Victoria A. Cornelius, Johnatas Dutra Silva, Akbar Satria Fitriawan, Jasenka Guduric-Fuchs, Asim Jamalabdalnaser A. Tashkandi, Refik Kuburas, Anna Zampetaki, et al.day 3, the medium was refreshed into N2B27 supplemented with 2 µM of forskolin (Biotechne, Cat. No. 1099/10) and 100 ng/mL human VEGF-A (Biotechne, Cat. No. NBC1-21277) for 2 days to induce budding of the ECs.

(8) HCMV infection disrupts barrier functions and promotes epithelial–mesenchymal transition in a cholangiocyte organoid modelNature CommunicationsFebruary 3, 2026Zuodong Ye, Xinyan Hu, Syed Mushfiqur Rahaman, Yuelan Zheng, Xiaoman Zhang, Clara Sze Man Tang, Tsz Man Yau, Wang Ka Lee, Patrick Ho Yu Chung, Kenneth Kak Yuen Wong, et al.cultured for 5 days PI and imaged 0, 3, 6, and 24 h after the addition of forskolin (10 µM; Cat. No. 1099/10; Tocris Bioscience) and 3-isobutyl-1-methylxanthine (IBMX, 100 µM; Sigma-Aldrich) using the Incucyte

(9) Activity-dependent extracellular proteolytic cascade cleaves the ECM component brevican to promote structural plasticityEMBO reportsJanuary 1, 2026Singh JB, Perelló-Amorós B, Schneeberg J, Mirzapourdelavar H, Seidenbecher CI, Fejtová A, Dityatev A, Frischknecht R.,Tocris Bioscience,1075 "6-Cyano-7-nitroquinoxaline-2,3-dione disodium (CNQX)",Tocris Bioscience,1045/1 Forskolin,Tocris Bioscience,1099/10 Rolipram,Tocris Bioscience,0905/10 Ro 25-6981,Tocris Bioscience,1594/10 TIMP3,R&D System,973-TM Tissue-Tek,Sakura,4583 "2,2,2-trichloroethanol",Merck,T54801 Antibodies,Antibodies,Antibodies Aggrecan

(10) DOCK10 Regulates Insulin Hypersecretion in Insulinoma and Serves as a Diagnostic and Therapeutic TargetCellular and Molecular Gastroenterology and HepatologyJanuary 1, 2026Hiromune Katsuda, Go Ito, Franziska Kimmig, Tomohiro Muto, Neha Mishra, Joana Pimenta Bernardes, Yui Hiraguri, Hironari Yamashita, Akira Ito, Yuko Kinowaki, et al.,Thermo Fisher,17502048,1×, Recombinant Human FGF10,Peprotech,100-26,100 ng/mL, Nicotinamide,Sigma,N0636,10 mM, FSK,Tocris,1099,10 μM, PGE2,Tocris,2296,3 μM, SB202190,Sigma-Aldrich,S7067-5mg,,10 μM Recombinant Mouse Wnt-3a,R&D Systems,1324-WN,,300

(11) The role of ciliary function in airway epithelial defense against Pseudomonas aeruginosaMed Microbiol ImmunolDecember 26, 2025Nina Boeck, Philipp Grubwieser, Rudolf Glueckert, Erika Kvalem Soto, Thomas Sonnweber, Alexander Hoffmann, Richard Hilbe, Stefanie Dichtl, Wilfried Posch, Manfred Nairz, et al.pharmacological compounds Where indicated, organoids were stimulated with either 10 µM Forskolin (Tocris, Cat#1099/10), 1 µM Roflumilast (MedChem Express, Cat#HY-100639) or 50 µM Pyocyanin (Sigma, Cat# R9532-500UL). In

(12) Modeling the Blood-Brain Barrier Using Human-Induced Pluripotent Stem CellsMethods in Molecular BiologyNovember 21, 2025Louise A. Mesentier-Louro, Natalie Suhy, Diede Broekaart, Michael Bula, Ana C. Pereira, Joel W. BlanchardCO2.Centrifuge Tubes.Disposable serological pipettes.Filtered pipette tips.Forskolin (R & D Systems, Cat. no. 1099/10).Geltrex™ LDEV-Free hESC-qualified Reduced Growth Factor Basement (Gibco, Cat. no. A1413302).Glass Bottom

(13) APOE4 promotes cerebrovascular fibrosis and amyloid deposition via a pericyte-to-myofibroblast transitionbioRxivSeptember 16, 2025Braxton R. Schuldt, Dominic Haworth-Staines, Andrea Perez-Arevalo, Diede W.M. Broekaart, Leon Wang, Georgia Gallagher, Grace Rabinowitz, Alison M. Goate, Towfique Raj, Ana C. Pereira, et al.D3072 FGF-basic,Peprotech,Cat# 100-18B Fibronectin,R&D Systems,Cat# 4305-FNB-200 Forkskolin,R&D Systems,Cat# 1099/10 Galunisertib,Tocris,Cat# 6956 GDNF,Peprotech,Cat# 450-10 Gelxtrex,Gibco,Cat# A1413201 GlutaMAX,Gibco,Cat#

(14) Periplakin Attenuates Liver Fibrosis via Reprogramming CD44Low Cells into CD44High Liver Progenitor CellsCellular and Molecular Gastroenterology and HepatologyMarch 17, 2025Lichao Zhang, Zhiyong Xiong, Zebin Chen, Meiyining Xu, Siyu Zhao, Xianzhi Liu, Kefeng Jiang, Yunyi Hu, Shurui Liu, Xi Sun, et al.N0636), and HGF (50 ng/mL, Peprotech, 315-23) 5 μM A83.01 (Tocris, 2939) and 10 μM Forskolin (Tocris, 1099/10). For in vivo experiments, mice were transplanted with sorted PPL+ CD44Low or CD44High cells via liver.

(15) Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancerOncogeneAugust 2, 2024Peter D. Haughton, Wisse Haakma, Theofilos Chalkiadakis, Gerben E. Breimer, Else Driehuis, Hans Clevers, Stefan Willems, Stefan Prekovic, Patrick W. B. DerksenSML0788-5MG), 5 ng/mL human FGF2 (PeproTech, catalog no. 100-18B), 1 μmol/L Forskolin (R&D Systems, catalog no. 1099), 10 ng/mL human FGF10 (PeproTech, catalog no. 100-26), 4% R-spondin and 4% Noggin (both produced via the

(16) Reconstruction of the Blood-Brain Barrier In Vitro to Model and Therapeutically Target Neurological DiseaseJournal of Visualized ExperimentsNovember 6, 2023Camille Goldman, Natalie Suhy, Jessica E. Schwarz, Emily Ruth Sartori, Rikki B. Rooklin, Braxton R. Schuldt, Louise A. Mesentier-Louro, Rikki Rooklin, Joel Blanchardmedium,Gibco,10565018, Doxycycline,Millipore-Sigma,D3072–1ML, FGF-basic,Peprotech,100–18B, Fluoromount-G slide mounting medium,VWR,100502–406, Forskolin,R&D Systems,1099/10, GeltrexTM LDEV-Free hESC-qualified Reduced Growth Factor Basement,Gibco,A1413302, Glass Bottom 48-well

(17) Photomodulation alleviates cellular senescence of aging adipose-derived stem cellsCell Communication and SignalingJune 19, 2023Tao Zhang, Yuqian He, Xin Shu, Xiaoyu Ma, Jiaqi Wu, Zuoqin Du, Jin Xu, Ni Chen, Jingcan You, Yaofang Liu, et al.bovine serum albumin, and stimulated with 5 nM S1P and/or 1 µM forskolin (Bio-Techne, Abingdon, UK, 1099/10) or were mock-stimulated, for 10 min at 37 °C. The medium was aspirated, and supernatant was collected

(18) Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neuronsCell reportsApril 25, 2023Sharma SD, Reddy BK, Pal R, Ritakari TE, Cooper JD, Selvaraj BT, Kind PC, Chandran S, Wyllie DJA, Chattarji S.,R&D Systems,257-NT-10 Poly-L-ornithine,Sigma-Aldrich,P4957 Laminin,Sigma-Aldrich,L2020 Fibronectin,Sigma-Aldrich,F2006 Forskolin,R&D Systems,1099/10 BDNF,R&D Systems,248-BDB-010 GDNF,R&D Systems,212-GD-050 Paraformaldehyde,Sigma-Aldrich,P6148 phosphate

(19) A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental useCommunications BiologyOctober 14, 2022Arif Ibrahim Ardisasmita, Imre F. Schene, Indi P. Joore, Gautam Kok, Delilah Hendriks, Benedetta Artegiani, Michal Mokry, Edward E. S. Nieuwenhuis, Sabine A. Fuchs50 μg/ml Primocin (Invivogen, ant-pm-2), 5 μM A83-01 (Tocris, 2939/10), and 10 μM Forskolin (Tocris, 1099/10). For the first 3 days after isolation from biopsies, the medium was supplemented with 30% Wnt conditioned

(20) Rabphilin-3A Drives Structural Modifications of Dendritic Spines Induced by Long-Term PotentiationCellsMay 11, 2022Franchini L, Stanic J, Barzasi M, Zianni E, Mauceri D, Diluca M, Gardoni F.Technologies), and goat anti-mouse Alexa Fluor 647 (#A21235, Life Technologies). 2.11. Reagents Forskolin (#1099/10), rolipram (#0905), and picrotoxin (#1128) were purchased from Tocris. NMDA (#M3262) and puromycin (#P8833)

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Forskolin

Forskolin from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

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Forskolin from Tocris Bioscience, a Bio-Techne Brand

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