BMS CCR2 22 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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BMS CCR2 22

High affinity, potent CCR2 antagonist

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Tocris Bioscience, a Bio-Techne Brand for
BMS CCR2 22

Description

High affinity, potent CCR2 antagonist

Product Specs
ItemBMS CCR2 22
CompanyTocris Bioscience, a Bio-Techne Brand
Price $182.00Supplier Page View Company Product Page
Catalog Number3129/1
Quantity1 mg (also 10 mg, 50 mg)
Purity98%
Molecular Weight593.66
Molecule Name2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
FormulaC28H34F3N5O4S
StorageStore at +4°C

Specifications/Features

Sizes Available: 1 mg (also 10 mg, 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancerCell death & diseaseAugust 29, 2022Wang YF, Yu L, Hu ZL, Fang YF, Shen YY, Song MF, Chen Y.

(2) Effect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarctionInternational journal of nanomedicineJanuary 1, 2018Wang J, Seo MJ, Deci MB, Weil BR, Canty JM, Nguyen J.

(3) CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasionMucosal immunologySeptember 1, 2017Liu J, Xue Y, Dong D, Xiao C, Lin C, Wang H, Song F, Fu T, Wang Z, Chen J, et al.

(4) M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migrationJournal of leukocyte biologyJune 1, 2016Barzilai S, Blecher-Gonen R, Barnett-Itzhaki Z, Zauberman A, Lebel-Haziv Y, Amit I, Alon R.

(5) Minocycline, a microglial inhibitor, blocks spinal CCL2-induced heat hyperalgesia and augmentation of glutamatergic transmission in substantia gelatinosa neuronsJournal of neuroinflammationJanuary 10, 2014Huang CY, Chen YL, Li AH, Lu JC, Wang HL.

(6) CCR2 acts as scavenger for CCL2 during monocyte chemotaxisPloS oneJanuary 1, 2012Volpe S, Cameroni E, Moepps B, Thelen S, Apuzzo T, Thelen M.

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