LFM-A13 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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LFM-A13

Potent, selective BTK inhibitor

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Tocris Bioscience, a Bio-Techne Brand for
LFM-A13

Description

Potent, selective BTK inhibitor

Product Specs
ItemLFM-A13
CompanyTocris Bioscience, a Bio-Techne Brand
Price $238.00Supplier Page View Company Product Page
Catalog Number1300/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight360
Molecule Name2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
FormulaC11H8Br2N2O2
StorageStore at RT

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Balancing tonic and phasic inhibition in hypothalamic corticotropin-releasing hormone neuronsThe Journal of physiologyMay 15, 2018Colmers PLW, Bains JS.

(2) Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal CancerInternational journal of molecular sciencesApril 23, 2018Tankiewicz-Kwedlo A, Hermanowicz JM, Pawlak K, Czarnomysy R, Bielawski K, Prokop I, Pawlak D.

(3) Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-κB pathwayOncotargetMay 23, 2017Wang F, Zhang W, Wang C, Fang X, Cheng H, Liu S, Chen XL.

(4) NEK7 is an essential mediator of NLRP3 activation downstream of potassium effluxNatureFebruary 18, 2016He Y, Zeng MY, Yang D, Motro B, Núñez G.

(5) STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human plateletsCellular signallingJune 1, 2012Lopez E, Jardin I, Berna-Erro A, Bermejo N, Salido GM, Sage SO, Rosado JA, Redondo PC.

(6) High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell deathProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2012Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K.

(7) Essential role of Stat3 in PI3K-induced oncogenic transformationProceedings of the National Academy of Sciences of the United States of AmericaAugust 9, 2011Hart JR, Liao L, Yates JR 3rd, Vogt PK.

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