UCL 1684 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemUCL 1684
CompanyTocris Bioscience, a Bio-Techne Brand
Price $266.00Supplier Page View Company Product Page
Catalog Number1310/5
Quantity5 mg
Purity97%
Molecular Weight654.44
Molecule Name6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo [b,n] [1,5,12,16]tetraazacyclotricosine-5,13-diium dibromide
FormulaC34H30Br2N4
StorageDesiccate at RT

Specifications/Features

Sizes Available: 5 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) A novel reticular node in the brainstem synchronizes neonatal mouse crying with breathingNeuronFebruary 16, 2022Wei XP, Collie M, Dempsey B, Fortin G, Yackle K.Mibefradil (10μM, Tocris, 219810), Iberiotoxin (50nM, Alomone Labs, STI-400), UCL1684 (50nM, Tocris, 13105). For pharmacological analysis of rhythmic activity, the drugs were added to the internal recording

(2) Oral Intake of EPA:DHA 6:1 by Middle-Aged Rats for One Week Improves Age-Related Endothelial Dysfunction in Both the Femoral Artery and Vein: Role of CyclooxygenasesInternational journal of molecular sciencesJanuary 30, 2020Gaertner S, Auger C, Farooq MA, Pollet B, Khemais-Benkhiat S, Niazi ZR, Schrevens S, Park SH, Toti F, Stephan D, et al.

(3) Knockdown of the small conductance Ca(2+) -activated K(+) channels is potently cytotoxic in breast cancer cell linesBritish journal of pharmacologyJanuary 1, 2016Abdulkareem ZA, Gee JM, Cox CD, Wann KT.

(4) 5-hydroxytryptamine has an endothelium-derived hyperpolarizing factor-like effect on coronary flow in isolated rat heartsJournal of biomedical scienceJune 16, 2015Chien CC, Su MJ.

(5) Changes in T-Lymphocytes' Viability After Laparoscopic Versus Open CholecystectomyInternational SurgeryApril 16, 2015Ilias P. Gomatos, Leonidas Alevizos, Olga Kalathaki, Harilaos Kantsos, Agapi Kataki, Emmanuel Leandros, George Zografos, Manousos Konstantoulakis(R&D Systems, Minneapolis, Minnesota), according to the manufacturer’s instructions. Briefly, 100 lL of cells (13105 13106 cells) were labeled fluorescently for detection of apoptotic and necrotic cells by adding 20

(6) Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic musclesAmerican journal of physiology. Cell physiologySeptember 15, 2014Kurahashi M, Mutafova-Yambolieva V, Koh SD, Sanders KM.

(7) New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1Molecular pharmacologySeptember 1, 2014Coleman N, Brown BM, Oliván-Viguera A, Singh V, Olmstead MM, Valero MS, Köhler R, Wulff H.

(8) TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cellsCellular & Molecular ImmunologyMarch 1, 2014Hongliang Fang, Bing Ang, Xinyun Xu, Xiaohui Huang, Yanfeng Wu, Yanping Sun, Wenying Wang, Nan Li, Xuetao Cao, Tao Wanmg/ml CT-26 tumor cell lysate antigen for 72 h and then collected and used as effector cells. BMDCs (13105) pulsed with CT-26 tumor lysate antigen, serving as stimulator cells, were cocultured with 23105 effector

(9) Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atriumHeart rhythmJune 1, 2013Hsueh CH, Chang PC, Hsieh YC, Reher T, Chen PS, Lin SF.

(10) Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somataJournal of neurophysiologyMay 1, 2013Benton MD, Lewis AH, Bant JS, Raman IM.

(11) Synaptic NMDA receptor-dependent Ca²⁺ entry drives membrane potential and Ca²⁺ oscillations in spinal ventral horn neuronsPloS oneJanuary 1, 2013Alpert MH, Alford S.

(12) Dynamic interplay of excitatory and inhibitory coupling modes of neuronal L-type calcium channelsAmerican journal of physiology. Cell physiologyApril 1, 2011Geier P, Lagler M, Boehm S, Kubista H.

(13) Allosteric block of KCa2 channels by apaminThe Journal of biological chemistryAugust 27, 2010Lamy C, Goodchild SJ, Weatherall KL, Jane DE, Liégeois JF, Seutin V, Marrion NV.

(14) Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic ratsBrain researchAugust 12, 2010Oliveira MS, Skinner F, Arshadmansab MF, Garcia I, Mello CF, Knaus HG, Ermolinsky BS, Otalora LF, Garrido-Sanabria ER.

(15) Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteriesThe Journal of pharmacology and experimental therapeuticsApril 1, 2010Hilgers RH, Janssen GM, Fazzi GE, De Mey JG.

(16) Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive ratsTranslational research : the journal of laboratory and clinical medicineOctober 1, 2009Giachini FR, Carneiro FS, Lima VV, Carneiro ZN, Dorrance A, Webb RC, Tostes RC.

(17) Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channelsThe Journal of biological chemistryJanuary 19, 2007Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

(18) Transforming growth factor-beta1 is a potent inhibitor of secretory leukoprotease inhibitor expression in a bronchial epithelial cell line. Munich Lung Transplant GroupEuropean Respiratory JournalJuly 8, 2000F. Jaumann, A. Elssner, G Mazur, S Dobmann, C Vogelmeier, for the Munich Lung Transplant Group378C. After 80% confluence had been reached, the cells were seeded into sixwell plates at a density of 13105 cells.well-1 to grow again to 80% confluence. This was followed by stimulation with: 1) TGF-b1 (R&D Systems

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UCL 1684

UCL 1684 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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UCL 1684 from Tocris Bioscience, a Bio-Techne Brand

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