DNQX from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemDNQX
CompanyTocris Bioscience, a Bio-Techne Brand
Price $90.00Supplier Page View Company Product Page
Catalog Number0189/10
Purity98%
Molecular Weight252.14
StorageStore at RT
FormulaC8H4N4O6
Molecule Name6,7-Dinitroquinoxaline-2,3-dione
Quantity10 mg (also 50 mg)

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Activity-dependent development of synaptic circuits mediates direction selectivity in an axis-specific mannerCell ReportsJuly 22, 2025Karina Bistrong, Rachana Deven Somaiya, Eugene Y. Liang, Benjamin E. Smith, Marla B. FellerA1420-10X1L Hexamethonium Bromide,Sigma,Cat# 501806478 DL-AP5,Tocris Biosciences,Cat# 010510 DNQX,Tocris Biosciences,Cat# 018910 Tetrodotoxin citrate,Tocris Biosciences,Cat# 1069 Alexa Fluor 594 Hydrazide,Molecular Probes,Cat#

(2) Schizophrenia-associated 22q11.2 deletion elevates striatal acetylcholine and disrupts thalamostriatal projections to produce amotivation in micebioRxivJune 24, 2025Mary H. Patton, Brett J.W. Teubner, Kristen T. Thomas, Sharon L. Freshour, Alexandra J. Trevisan, Andrew B. Schild, Cody A. Ramirez, Jay B. Bikoff, Stanislav S. ZakharenkoCGP 55845 hydrochloride,Tocris Bioscience,Cat #1248 AP5,Tocris Bioscience,Cat #0106 DNQX,Tocris Bioscience,Cat #018910 TTX,Tocris Bioscience,Cat #1069 Actinomycin D,Sigma,Cat #A1410 DREADD agonist 21 dihydrochloride

(3) Expression of GAD2 in excitatory neurons projecting from the ventrolateral periaqueductal gray to the locus coeruleusiScienceJune 21, 2024Erika K. Harding, Zizhen Zhang, Julia Canet-Pons, Sierra Stokes-Heck, Tuan Trang, Gerald W. Zamponi(4-aminopyridine),Millipore Sigma,Cat#A-0152 Bicuculline methochloride,Tocris,Cat#0131/10 DNQX,Tocris,Cat#0189/10 QX 314 chloride,Tocris,Cat#2313/50 ,, Experimental models: Organisms/strains,Experimental models:

(4) The brain-specific kinase LMTK3 regulates neuronal excitability by decreasing KCC2-dependent neuronal Cl− extrusioniScienceApril 19, 2024Noell Cho, Georgina Kontou, Joshua L. Smalley, Christopher Bope, Jacob Dengler, Kristopher Montrose, Tarek Z. Deeb, Nicholas J. Brandon, Tadashi Yamamoto, Paul A. Davies, et al.Kynurenic Acid,Tocris,Tocris,0223 Tetrodotoxin,Tocris,Tocris,2805/50 Bumetanide,Tocris,Tocris,1078/1 Muscimol,Tocris,Tocris,3108/50 DNQX,Tocris,Tocris,0189/10 VU0463271,Tocris,Tocris,0219/1G 4-aminopyridine,Tocris,Tocris,0940/100 ,,, Software and algorithms,Software

(5) Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterationsiScienceJanuary 20, 2023Martina Sgritta, Beatrice Vignoli, Domenico Pimpinella, Marilena Griguoli, Spartaco Santi, Andrzej Bialowas, Grzegorz Wiera, Paola Zacchi, Francesca Malerba, Cristina Marchetti, et al.proteins" ,, "D-(−)-2-amino-5-phosphonopentaoic acid (D-AP5), 6,7-dinitroquinoxaline-2,3-dione (DNQX)",Tocris,Cat#0189/10 L-(+)-2-Amino-4-phosphonobutyric acid (L-AP4),Tocris,Cat#0103/1 "(2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)

(6) Fast and slow feedforward inhibitory circuits for cortical odor processingeLifeMarch 17, 2022Norimitsu Suzuki, Malinda L S Tantirigama, K Phyu Aung, Helena H Y Huang, John M Bekkerssaturated vapor pressure "Chemical compound, drug",DNQX,Tocris,"6,7-Dinitroquinoxaline-2,3-dione,Cat # 0189",10 µM "Chemical compound, drug",D-AP5,Tocris,"D-aminophosphono valeric acid,Cat # 0106",50 µM "Chemical

(7) Hyperexcitable arousal circuits drive sleep instability during agingScience (New York, N.Y.)February 25, 2022Li SB, Damonte VM, Chen C, Wang GX, Kebschull JM, Yamaguchi H, Bian WJ, Purmann C, Pattni R, Urban AE, et al.receptors and GABAA receptors were blocked by 6,7-dinitroquinoxaline-2,3-dione (DNQX, Tocris Cat. no. 0189, 10 μM), strychnine (Sigma-Aldrich Cat. no. S0532, 1 μM), (2R)-amino-5-phosphonopentanoate (APV, Tocris

(8) nGnG Amacrine Cells and Brn3b-negative M1 ipRGCs are Specifically Labeled in the ChAT-ChR2-EYFP MouseInvestigative ophthalmology & visual scienceFebruary 7, 2020Cui LJ, Chen WH, Liu AL, Han X, Jiang SX, Yuan F, Zhong YM, Yang XL, Weng SJ.

(9) Gap Junction Coupling Shapes the Encoding of Light in the Developing RetinaCurrent biology : CBDecember 2, 2019Caval-Holme F, Zhang Y, Feller MB.0925 D-2-amino-5-phosphonovalerate (D-AP5),Tocris,Cat# 0106 "6,7-Dinitroquinoxaline-2,3-dione (DNQX)",Tocris,Cat# 0189/10 Critical Commercial Assays,Critical Commercial Assays,Critical Commercial Assays ,, ,, ,, ,, ,, Deposited

(10) A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived NeuronsCell reportsMay 14, 2019Meijer M, Rehbach K, Brunner JW, Classen JA, Lammertse HCA, van Linge LA, Schut D, Krutenko T, Hebisch M, Cornelisse LN, et al.

(11) Somatostatin Interneurons Promote Neuronal Synchrony in the Neonatal HippocampusCell reportsMarch 19, 2019Flossmann T, Kaas T, Rahmati V, Kiebel SJ, Witte OW, Holthoff K, Kirmse K.

(12) Dopamine Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of Dopamine and GlutamateCell reportsDecember 11, 2018Cai Y, Ford CP.

(13) A Self-Regulating Gap Junction Network of Amacrine Cells Controls Nitric Oxide Release in the RetinaNeuronDecember 5, 2018Jacoby J, Nath A, Jessen ZF, Schwartz GW.,Vector Labs,H-1000 Alexa Fluor 488,Life Technologies,A10436 Oregon Green BAPTA-1,Life Technologies,O-6806 DNQX,Tocris,0189/10 L-AP4,Tocris,0103 D-AP5,Tocris,0106/1 Cobalt(II) Chloride hexahydrate,Sigma-Aldrich,255599 L-NAME,Sigma-Aldrich,N5751 MFA,Sigma-Aldrich,M4531 Amphotericin,Sigma-Aldrich,A9528 ,, Software

(14) Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disordersMolecular psychiatryAugust 1, 2018Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, et al.

(15) Activity-Dependent Downscaling of Subthreshold Synaptic Inputs during Slow-Wave-Sleep-like Activity In VivoNeuronMarch 21, 2018González-Rueda A, Pedrosa V, Feord RC, Clopath C, Paulsen O.

(16) Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesisNature communicationsMarch 8, 2018Ferlauto L, Airaghi Leccardi MJI, Chenais NAL, Gilliéron SCA, Vagni P, Bevilacqua M, Wolfensberger TJ, Sivula K, Ghezzi D.

(17) HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salienceNature communicationsAugust 4, 2017Raza SA, Albrecht A, Çalışkan G, Müller B, Demiray YE, Ludewig S, Meis S, Faber N, Hartig R, Schraven B, et al.

(18) Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampusCell researchJune 1, 2016Zhang Y, Cao SX, Sun P, He HY, Yang CH, Chen XJ, Shen CJ, Wang XD, Chen Z, Berg DK, et al.

(19) Fixed single-cell transcriptomic characterization of human radial glial diversityNature methodsJanuary 1, 2016Thomsen ER, Mich JK, Yao Z, Hodge RD, Doyle AM, Jang S, Shehata SI, Nelson AM, Shapovalova NV, Levi BP, et al.

(20) Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) MiceFrontiers in cellular neuroscienceJanuary 1, 2016Fan J, Stemkowski PL, Gandini MA, Black SA, Zhang Z, Souza IA, Chen L, Zamponi GW.

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DNQX

DNQX

DNQX from Tocris Bioscience, a Bio-Techne Brand

Description

Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (126)

Reviews

DNQX from Tocris Bioscience, a Bio-Techne Brand

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